| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 23rd, 2004 | 14 | No |
Popular Name: Levamisole hydrochloride Levamisole hydrochloride
Find On: PubMed — Wikipedia — Google
CAS Numbers: 14769-73-4 , 16595-80-5 , 16595-80-5, 14769-73-4 [l , 16595-80-5, 14769-73-4 [levamisole] , 32093-35-9 , 5036-02-2 , 5086-74-8 , [14769-73-4] , [16595-80-5] , [32093-35-9] , [5036-02-2] , [5086-74-8]
"Levamisol hydrochloride, 99%"
(6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole
(6S)-6-phenyl-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole hydrochloride
(S)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazoletriylium phosphate
(S)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride
(S)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole phosphate
16595-80-5; D00750; Ergamisol (TN); Levamisole hydrochloride (USP)
2,3,5,6-Tetrahydro-6-phenyl-imidazo[2,1-b]thiazole, (S)-
5036-02-2; Ascaverm (TN); D08576; Tetramisole (INN); Tetramisole [veterinary] (TN)
5086-74-8; C11337; Tetramisole hydrochloride
5086-74-8; D06091; Tetramisole hydrochloride (USAN)
5086-74-8; Prestwick_854; Tetramisole hydrochloride
6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole
6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole
6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole hydrochloride
Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, (6S)-
Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, (S)-
INN); Tetramisole Hydrochloride (USAN)
Ketrax; Lepuron; Levomysol; Levovermax; Totalon; Wormicid
L-2,3,5,6-Tetrahyro-6-phenylimidazo(2,1-b)thiazole
levamisol; levamisole; levamisolum
Levamisole Hydrochloride [for Biochemical Research]
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.08 | 6.66 | -26.75 | 1 | 2 | 1 | 17 | 205.306 | 1 | ↓ |
| Hi High (pH 8-9.5) | 2.08 | 5.66 | -8.22 | 0 | 2 | 0 | 16 | 204.298 | 1 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| ALOGPS_SOLUBILITY | 1.44e+00 g/l | DrugBank-approved |
| Mp [°C] | 226 - 231 | Acros Organics |
| MP | 230 | TCI |
| purity | 9.500000000000000e+001 | Enamine Building Blocks Enamine Building Blocks |
| Purity | 95% | Fluorochem |
| Purity | 98.0-101.0% | APIChem |
| Purity | >99% | APIChem |
| UniProt Database Links | ACH1_CAEBR; ACH1_CAEEL; ACH6_CAEEL; ACH7_CAEEL; LNP1_CAEEL; RAPSN_CAEEL; TPM1_CAEEL; TPM3_CAEEL; TPM_CAEBR | ChEBI |
| Target | Angiogenesis | Selleck Chemicals |
| Indications | anthelmintic | KeyOrganics Bioactives |
| H phrase | H301: Toxic if swallowed | Acros Organics |
| Target | Immunology & Inflammation related | Selleck Chemicals |
| Therapy | immunomodulator | SMDC MicroSource |
| P phrase | P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician | Acros Organics |
| R phrase | R25: Toxic if swallowed. | Acros Organics |
| S phrase | S28A: After contact with skin, wash immediately with plenty of water. | Acros Organics |
| S phrase | S28A: After contact with skin, wash immediately with plenty of water.; S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). | Acros Organics |
| Hazard | T: Toxic | Acros Organics |
| PUBCHEM_PATENT_ID | US4618618 | IBM Patent Data |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z100715-1-O | Nippostrongylus Brasiliensis (cluster #1 Of 2), Other | Other | 210 | 0.67 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z100715 | Z100715 | Nippostrongylus Brasiliensis | 210 | 0.67 | Functional ≤ 10μM |
