| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 23rd, 2004 | 17 | Yes |
Popular Name: Sulfadiazine Sulfadiazine
Find On: PubMed — Wikipedia — Google
CAS Numbers: 116-44-9 , 127-79-7 , 22199-08-2 , 547-32-0 , 68-35-9 , 68-39-9 , [127-79-7] , [547-32-0] , [68-35-9]
"Sulfazinum; Adiazin; Debenal; Pirimal; Pyrimal; Sulfadiazin; Sulfapyrazine"
(4-Amino-N-pyrimidin-2-ylbenzenesulphonamidato-NN,O1)silver
2-Sulfanilamidopyrimidin [German]
22199-08-2; D00433; Silvadene (TN); Sulfadiazine silver (JP16); Sulfadiazine, silver (USP)
4-Amino-N-(2-pyrimidinyl)benzenesulfonamide
4-Amino-N-(2-pyrimidinyl)benzenesulfonamide silver salt
4-Amino-N-(2-pyrimidinyl)benzenesulfonamide sodium salt
4-Amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide
4-amino-N-(pyrimidin-2-yl)benzene-1-sulfonamide
4-amino-N-(pyrimidin-2-yl)benzenesulfonamide
4-Amino-N-2-pyrimidinyl- benzenesulfonamide
4-Amino-N-2-pyrimidinyl-benzenesulfonamide
4-AMINO-N-2-PYRIMIDINYLBENZENESULFONAMIDE
4-Amino-N-pyrimidin-2-yl-benzenesulfonamide
4-Amino-N-pyrimidin-2-ylbenzenesulfonamide
4-amino-N-pyrimidin-2-ylbenzenesulfonamide monosilver(1+) salt
4-Azanyl-N-(4-methylpyrimidin-2-yl)benzenesulfonamide
5-25-10-00067 (Beilstein Handbook Reference)
547-32-0; D05949; Sulfadiazine sodium (TN); Sulfadiazine sodium (USP)
68-35-9; D00587; Sulfadiazine (JAN/USP/INN); Sulfadiazine (TN); Sulfapyrimidine
68-35-9; Prestwick_428; Sulfadiazine
Abbott Brand of Silver Sulfadiazine
Adiazin, Adiazine, Debenal, Liquadiazine
Adiazin, Adiazine, Debenal, Liquadiazine, Microsulfon, Sulfazine, Sulfolex, Sulfadiazine
Aldo Brand of Silver Sulfadiazine
AMINOPYRIMIDINYLBENZENESULFONAMID
Benzenesulfonamide, 4-amino-N-2-pyrimidinyl-
benzenesulfonamide, 4-amino-N-2-pyrimidinyl-, monosilver(1+) salt
Benzenesulfonamide,4-amino-N-2-pyrimidinyl-, silver complex
Major Brand of Silver Sulfadiazine
medphano Brand of Silver Sulfadiazine
Mixture of sulfadiazine, sulfamerazine, and sulfamethazine
Monarch Brand of Silver Sulfadiazine
N(1)-(2-Pyrimidinyl)sulfanilamide
N(1)-2-pyrimidinylsulfanilamide
N(sup 1)-2-Pyrimidinylsulfanilamide
N(sup 1)-2-Pyrimidinylsulfanilamide monosilver(1+) salt
N(sup1)-2-Pyrimidinylsulfanilamide
N(sup1)-2-Pyrimidylsulfanilamide
N-(2-Pyrimidinyl)sulfanilamide
N1-(Pyrimidin-2-yl)sulfanilamide
N1-2-Pyrimidinylsulfanilamide monosilver(1+) salt
Par Brand 1 of Silver Sulfadiazine
Par Brand 2 of Silver Sulfadiazine
Par Brand 3 of Silver Sulfadiazine
Pharmascience Brand of Silver Sulfadiazine
Recombinant bactericidal/permeability-increasing protein & Sulfadiazine
Rhone Poulenc Rorer Brand of Silver Sulfadiazine
Rhone-Poulenc Rorer Brand of Silver Sulfadiazine
Sherwood Brand of Silver Sulfadiazine
silver (4-aminophenyl)sulfonyl-pyrimidin-2-ylazanide
silver 4-amino-N-pyrimidin-2-ylbenzenesulfonamide
Silver sulfadiazinate;Silver sulphadiazine;SSD;Sulfadiazine silver
Silver(1+) [(4-aminophenyl)sulfonyl](2-pyrimidinyl)azanide
silver(1+) [(4-aminophenyl)sulfonyl](pyrimidin-2-yl)azanide
Silver, (4-amino-N-2-pyrimidinylbenzenesulfonamidato-NN,O1)-
Silver, [4-amino-N-(2-pyrimidinyl-.kappa.N1) benzenesulfonamidato-.kappa.O]-
Silver,(4-amino-N-2-pyrimidinylbenzenesulfonamidato-NN,O1)-
Smith & Nephew Brand of Silver Sulfadiazine
Solvay Brand of Silver Sulfadiazine
SSD (1% Silver Sulfadiazine Cream USP)
sulfadiazina; sulfadiazine; sulfadiazinum
Sulfadiazine (Trisulfapyrimidines) (FDA); Sulfadiazine (BAN
Sulfadiazine Silver (JAN); Silver Sulfadiazine (FDA); Sulfadiazine
Sulfanilamide, N(sup 1)-2-pyrimidinyl-
Sulfanilamide, N(sup 1)-2-pyrimidinyl-, monosilver(1+) salt
Sulfanilamide, N1-2(1H)-pyrimidinylidene-
Sulfanilamide, N1-2-pyrimidinyl-
Sulfanilamide, N1-2-pyrimidinyl- (8CI)
Sulfanilamide,N1-2-pyrimidinyl-, monosilver(1+) salt
Sulfazinum; Adiazin; Debenal; Pirimal; Pyrimal; Sulfadiazin; Sulfapyrazine
Trisulfapyrimidine, oral suspension
USP); Silver Sulfadiazine (FDA); Sulfadiazine Silver (JAN); Sulfadiazine
USP); Sulfadiazine (Trisulfapyrimidines) (FDA); Sulfadiazine Sodium (INN
USP); Sulfadiazine Sodium (FDA
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -0.04 | 2.34 | -13.69 | 3 | 6 | 0 | 98 | 250.283 | 3 | ↓ |
| Mid Mid (pH 6-8) | -0.04 | 2.01 | -53.73 | 2 | 6 | -1 | 100 | 249.275 | 3 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| MP | 253 - 255 | Enamine Building Blocks |
| Melting_Point | 253-256? | Alfa-Aesar |
| Melting_Point | 253-256° | Alfa-Aesar |
| MP | 253...255 | Enamine Building Blocks |
| MP | 255° | Matrix Scientific |
| ALOGPS_SOLUBILITY | 6.01e-01 g/l | DrugBank-approved |
| ALOGPS_SOLUBILITY | 7.87e+00 g/l | DrugBank-approved |
| purity | 9.500000000000000e+001 | Enamine Building Blocks Enamine Building Blocks |
| Therapy | antibacterial | SMDC Iconix |
| biological_use | Antibacterial agent | IBScreen Bioactives IBScreen Bioactives |
| Target | Antifection | Selleck Chemicals |
| Patent Database Links | EP1514877; EP1537858; EP1538164; EP1611879; EP1625855; EP1671624; EP1685843; EP1717247; GB2084566; US2003105066; US2004254182; US2006235023; US2007202051; US2007202077; US2007203079; US2007207222; US2007232718; US2007244259; US2007248645; US2007248660; US | ChEBI |
| mechanism | Folate antagonist | IBScreen Bioactives IBScreen Bioactives |
| mechanism | Folate synthesis inhibitor | IBScreen Bioactives |
| Warnings | IRRITANT | Matrix Scientific |
| Target | Others | Selleck Chemicals |
| mechanism | Restrict folate synthesis through competitive antagonism of PABA | IBScreen Bioactives |
| Indications | sulphonamide antibiotic | KeyOrganics Bioactives |
| biological_use | Used in some countries for control of bacterial disease in farmed fish | IBScreen Bioactives |
