| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 26th, 2005 | 19 | Yes |
Popular Name: orphan orphan
Find On: PubMed — Wikipedia — Google
CAS Numbers: 125-73-5 , 143-98-6 , 69376-27-8
(+)-3-HYDROXY-N-METHYLMORPHINAN D-TARTRATE; 3-Hydroxy-N-methylmorphinan; CPD000058908; SAM001247023
(+)-3-HYDROXY-N-METHYLMORPHINAN D-TARTRATE; CPD000058908; SAM001247023
(+)-3-hydroxy-N-methylmorphinan; d-3-hydroxy-N-methylmorphinan
1,3,4,9,10,10A-hexahydro-6-hydroxy-2h-10,4a-(iminoethano)-11-methylphenanthrene
69376-27-8; D03746; Dextrorphan hydrochloride (USAN)
CPD000058908; (+)-3-HYDROXY-N-METHYLMORPHINAN D-TARTRATE
dextrorphan; dextrorphane; dextrorphanum
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.40 | 6.71 | -39.89 | 2 | 2 | 1 | 25 | 258.385 | 0 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| PUBCHEM_PATENT_ID | EP0219896A1; EP0219896B1; EP0270290A2; EP0323762A1; EP0323762B1; EP0346445A1; EP0359215A1; EP0359215B1; EP0369334A2; EP0371085A1; EP0495889A1; EP0529898A1; EP0543919B1; EP0573548A1; EP0573548B1; EP0608893A1; EP0612845A3; EP0615749A2; EP0615749A3; EP061761 | IBM Patent Data |
| Patent Database Links | EP1559418; EP1649857; EP1902733; US2008234257; WO2007087452; WO2008140859 | ChEBI |
| PUBCHEM_SUBSTANCE_COMMENT | NCC_SAMPLE_SUPPLIER : Tocris Cookson Ltd.; NCC_SUPPLIER_STRUCTURE_ID : 100721; 1 tartaric acid | NIH Clinical Collection via PubChem |
| Reactome Database Links | REACT_323 | ChEBI |
| PUBCHEM_SUBSTANCE_COMMENT | SAMPLE_SUPPLIER: Tocris Bioscience; SUPPLIER_STRUCTURE_ID: 100721; SALT: 1 tartaric acid | NIH Clinical Collection via PubChem |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| OPRD-1-E | Delta Opioid Receptor (cluster #1 Of 3), Eukaryotic | Eukaryotes | 57 | 0.53 | Binding ≤ 10μM |
| OPRK-1-E | Kappa Opioid Receptor (cluster #1 Of 6), Eukaryotic | Eukaryotes | 57 | 0.53 | Binding ≤ 10μM |
| OPRM-1-E | Mu-type Opioid Receptor (cluster #1 Of 4), Eukaryotic | Eukaryotes | 57 | 0.53 | Binding ≤ 10μM |
| SGMR1-1-E | Sigma Opioid Receptor (cluster #1 Of 6), Eukaryotic | Eukaryotes | 57 | 0.53 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| OPRD_RAT | P33533 | Delta Opioid Receptor, Rat | 4.84 | 0.61 | Binding ≤ 1μM |
| OPRK_RAT | P34975 | Kappa Opioid Receptor, Rat | 4.84 | 0.61 | Binding ≤ 1μM |
| OPRM_RAT | P33535 | Mu Opioid Receptor, Rat | 4.84 | 0.61 | Binding ≤ 1μM |
| SGMR1_RAT | Q9R0C9 | Sigma Opioid Receptor, Rat | 4.84 | 0.61 | Binding ≤ 1μM |
| OPRD_RAT | P33533 | Delta Opioid Receptor, Rat | 4.84 | 0.61 | Binding ≤ 10μM |
| OPRK_RAT | P34975 | Kappa Opioid Receptor, Rat | 4.84 | 0.61 | Binding ≤ 10μM |
| OPRM_RAT | P33535 | Mu Opioid Receptor, Rat | 4.84 | 0.61 | Binding ≤ 10μM |
| SGMR1_RAT | Q9R0C9 | Sigma Opioid Receptor, Rat | 4.84 | 0.61 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Xenobiotics |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| G-protein activation | |
| Opioid Signalling | |
| Peptide ligand-binding receptors |
