| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 21st, 2008 | 26 | Yes |
Popular Name: Protirelin Protirelin
Find On: PubMed — Wikipedia — Google
CAS Numbers: 24305-27-9 , [24305-27-9]
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -2.03 | 0.05 | -22.94 | 5 | 10 | 0 | 150 | 362.39 | 6 | ↓ |
| Ref Reference (pH 7) | -2.03 | -0.84 | -25.97 | 5 | 10 | 0 | 150 | 362.39 | 6 | ↓ |
| Mid Mid (pH 6-8) | -2.03 | -0.39 | -50.76 | 6 | 10 | 1 | 152 | 363.398 | 6 | ↓ |
| Mid Mid (pH 6-8) | -2.03 | -0.32 | -50.65 | 6 | 10 | 1 | 152 | 363.398 | 6 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| Therapy | prothyrotropin | SMDC Pharmakon |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TRFR-1-E | Thyrotropin-releasing Hormone Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 42 | 0.40 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TRFR_RAT | Q01717 | Thyrotropin-releasing Hormone Receptor, Rat | 42.3 | 0.40 | Binding ≤ 1μM |
| TRFR_RAT | Q01717 | Thyrotropin-releasing Hormone Receptor, Rat | 42.3 | 0.40 | Binding ≤ 10μM |
