Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-4.59	-7.22	-83.63	11	15	0	261	471.471	7	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	-4.59	-9.22	-50.26	12	15	1	258	472.479	7	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	-4.66	-9.17	-50.13	12	15	1	260	472.479	6	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
ITAV-1-E	Vitronectin Receptor Alpha (cluster #1 Of 1), Eukaryotic	Eukaryotes	412	0.27	Binding ≤ 10μM
ITB5-1-E	Integrin Beta-5 (cluster #1 Of 1), Eukaryotic	Eukaryotes	412	0.27	Binding ≤ 10μM
Z104292-1-O	Integrin Alpha-V/beta-3 (cluster #1 Of 1), Other	Other	133	0.29	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
Z104292	Z104292	Integrin Alpha-V/beta-3	132.9	0.29	Binding ≤ 1μM
ITB5_HUMAN	P18084	Integrin Beta-5, Human	411.5	0.27	Binding ≤ 1μM
ITAV_HUMAN	P06756	Vitronectin Receptor Alpha, Human	411.5	0.27	Binding ≤ 1μM
Z104292	Z104292	Integrin Alpha-V/beta-3	132.9	0.29	Binding ≤ 10μM
ITB5_HUMAN	P18084	Integrin Beta-5, Human	411.5	0.27	Binding ≤ 10μM
ITAV_HUMAN	P06756	Vitronectin Receptor Alpha, Human	411.5	0.27	Binding ≤ 10μM

Description	Species
Cross-presentation of particulate exogenous antigens (phagosomes)	Homo sapiens (ITAV_HUMAN)
ECM proteoglycans	Homo sapiens (ITAV_HUMAN)
Elastic fibre formation	Homo sapiens (ITAV_HUMAN)
Integrin cell surface interactions	Homo sapiens (ITAV_HUMAN)
Laminin interactions	Homo sapiens (ITAV_HUMAN)
Molecules associated with elastic fibres	Homo sapiens (ITAV_HUMAN)
PECAM1 interactions	Homo sapiens (ITAV_HUMAN)
Signal transduction by L1	Homo sapiens (ITAV_HUMAN)
Smooth Muscle Contraction	Homo sapiens (ITB5_HUMAN)
Syndecan interactions	Homo sapiens (ITAV_HUMAN)
VEGFA-VEGFR2 Pathway	Homo sapiens (ITAV_HUMAN)