Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-3.89	-4.4	-80.11	10	14	0	240	455.472	7	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	-3.89	-6.39	-51.92	11	14	1	238	456.48	7	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	-4.02	-6.34	-51.79	11	14	1	240	456.48	6	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
ITAV-1-E	Vitronectin Receptor Alpha (cluster #1 Of 1), Eukaryotic	Eukaryotes	30	0.33	Binding ≤ 10μM
ITB5-1-E	Integrin Beta-5 (cluster #1 Of 1), Eukaryotic	Eukaryotes	30	0.33	Binding ≤ 10μM
Z104292-1-O	Integrin Alpha-V/beta-3 (cluster #1 Of 1), Other	Other	36	0.33	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
Z104292	Z104292	Integrin Alpha-V/beta-3	35.6	0.33	Binding ≤ 1μM
ITB5_HUMAN	P18084	Integrin Beta-5, Human	29.6	0.33	Binding ≤ 1μM
ITAV_HUMAN	P06756	Vitronectin Receptor Alpha, Human	29.6	0.33	Binding ≤ 1μM
Z104292	Z104292	Integrin Alpha-V/beta-3	35.6	0.33	Binding ≤ 10μM
ITB5_HUMAN	P18084	Integrin Beta-5, Human	29.6	0.33	Binding ≤ 10μM
ITAV_HUMAN	P06756	Vitronectin Receptor Alpha, Human	29.6	0.33	Binding ≤ 10μM

Description	Species
Cross-presentation of particulate exogenous antigens (phagosomes)	Homo sapiens (ITAV_HUMAN)
ECM proteoglycans	Homo sapiens (ITAV_HUMAN)
Elastic fibre formation	Homo sapiens (ITAV_HUMAN)
Integrin cell surface interactions	Homo sapiens (ITAV_HUMAN)
Laminin interactions	Homo sapiens (ITAV_HUMAN)
Molecules associated with elastic fibres	Homo sapiens (ITAV_HUMAN)
PECAM1 interactions	Homo sapiens (ITAV_HUMAN)
Signal transduction by L1	Homo sapiens (ITAV_HUMAN)
Smooth Muscle Contraction	Homo sapiens (ITB5_HUMAN)
Syndecan interactions	Homo sapiens (ITAV_HUMAN)
VEGFA-VEGFR2 Pathway	Homo sapiens (ITAV_HUMAN)