Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-2.98	-2.36	-80.9	9	13	0	220	439.473	7	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	-2.98	-4.34	-47.72	10	13	1	217	440.481	7	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	-3.10	-4.29	-47.7	10	13	1	220	440.481	6	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
ITAV-1-E	Vitronectin Receptor Alpha (cluster #1 Of 1), Eukaryotic	Eukaryotes	7	0.37	Binding ≤ 10μM
ITB5-1-E	Integrin Beta-5 (cluster #1 Of 1), Eukaryotic	Eukaryotes	7	0.37	Binding ≤ 10μM
Z104292-1-O	Integrin Alpha-V/beta-3 (cluster #1 Of 1), Other	Other	8	0.37	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
Z104292	Z104292	Integrin Alpha-V/beta-3	7.7	0.37	Binding ≤ 1μM
ITB5_HUMAN	P18084	Integrin Beta-5, Human	6.56	0.37	Binding ≤ 1μM
ITAV_HUMAN	P06756	Vitronectin Receptor Alpha, Human	6.56	0.37	Binding ≤ 1μM
Z104292	Z104292	Integrin Alpha-V/beta-3	7.7	0.37	Binding ≤ 10μM
ITB5_HUMAN	P18084	Integrin Beta-5, Human	6.56	0.37	Binding ≤ 10μM
ITAV_HUMAN	P06756	Vitronectin Receptor Alpha, Human	6.56	0.37	Binding ≤ 10μM

Description	Species
Cross-presentation of particulate exogenous antigens (phagosomes)	Homo sapiens (ITAV_HUMAN)
ECM proteoglycans	Homo sapiens (ITAV_HUMAN)
Elastic fibre formation	Homo sapiens (ITAV_HUMAN)
Integrin cell surface interactions	Homo sapiens (ITAV_HUMAN)
Laminin interactions	Homo sapiens (ITAV_HUMAN)
Molecules associated with elastic fibres	Homo sapiens (ITAV_HUMAN)
PECAM1 interactions	Homo sapiens (ITAV_HUMAN)
Signal transduction by L1	Homo sapiens (ITAV_HUMAN)
Smooth Muscle Contraction	Homo sapiens (ITB5_HUMAN)
Syndecan interactions	Homo sapiens (ITAV_HUMAN)
VEGFA-VEGFR2 Pathway	Homo sapiens (ITAV_HUMAN)