Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.13	8.08	-6.02	0	2	0	22	237.302	2	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	3.13	8.35	-36.33	1	2	1	23	238.31	2	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
C11B1-1-E	Cytochrome P450 11B1 (cluster #1 Of 2), Eukaryotic	Eukaryotes	578	0.49	Binding ≤ 10μM
C11B2-1-E	Cytochrome P450 11B2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	2	0.68	Binding ≤ 10μM
CP19A-1-E	Cytochrome P450 19A1 (cluster #1 Of 3), Eukaryotic	Eukaryotes	814	0.47	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
C11B1_HUMAN	P15538	Cytochrome P450 11B1, Human	578	0.49	Binding ≤ 1μM
C11B2_HUMAN	P19099	Cytochrome P450 11B2, Human	2	0.68	Binding ≤ 1μM
CP19A_HUMAN	P11511	Cytochrome P450 19A1, Human	814	0.47	Binding ≤ 1μM
C11B1_HUMAN	P15538	Cytochrome P450 11B1, Human	578	0.49	Binding ≤ 10μM
C11B2_HUMAN	P19099	Cytochrome P450 11B2, Human	2	0.68	Binding ≤ 10μM
CP19A_HUMAN	P11511	Cytochrome P450 19A1, Human	814	0.47	Binding ≤ 10μM

Description	Species
Endogenous sterols	Homo sapiens (CP19A_HUMAN)
Estrogen biosynthesis	Homo sapiens (CP19A_HUMAN)
Glucocorticoid biosynthesis	Homo sapiens (C11B1_HUMAN)
Mineralocorticoid biosynthesis	Homo sapiens (C11B1_HUMAN)