| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 27th, 2008 | 36 | No |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.75 | 16.53 | -40.49 | 1 | 4 | 1 | 38 | 528.544 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CCR1-1-E | C-C Chemokine Receptor Type 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 740 | 0.24 | Binding ≤ 10μM |
| CCR3-1-E | C-C Chemokine Receptor Type 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 460 | 0.25 | Binding ≤ 10μM |
| CCR1-1-E | C-C Chemokine Receptor Type 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 21 | 0.30 | Functional ≤ 10μM |
| CCR3-1-E | C-C Chemokine Receptor Type 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 350 | 0.25 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CCR1_MOUSE | P51675 | C-C Chemokine Receptor Type 1, Mouse | 12 | 0.31 | Binding ≤ 1μM |
| CCR1_HUMAN | P32246 | C-C Chemokine Receptor Type 1, Human | 0.9 | 0.35 | Binding ≤ 1μM |
| CCR3_MOUSE | P51678 | C-C Chemokine Receptor Type 3, Mouse | 460 | 0.25 | Binding ≤ 1μM |
| CCR3_HUMAN | P51677 | C-C Chemokine Receptor Type 3, Human | 0.58 | 0.36 | Binding ≤ 1μM |
| CCR1_HUMAN | P32246 | C-C Chemokine Receptor Type 1, Human | 0.9 | 0.35 | Binding ≤ 10μM |
| CCR1_MOUSE | P51675 | C-C Chemokine Receptor Type 1, Mouse | 12 | 0.31 | Binding ≤ 10μM |
| CCR3_MOUSE | P51678 | C-C Chemokine Receptor Type 3, Mouse | 460 | 0.25 | Binding ≤ 10μM |
| CCR3_HUMAN | P51677 | C-C Chemokine Receptor Type 3, Human | 0.58 | 0.36 | Binding ≤ 10μM |
| CCR1_MOUSE | P51675 | C-C Chemokine Receptor Type 1, Mouse | 21 | 0.30 | Functional ≤ 10μM |
| CCR1_HUMAN | P32246 | C-C Chemokine Receptor Type 1, Human | 0.73 | 0.36 | Functional ≤ 10μM |
| CCR3_MOUSE | P51678 | C-C Chemokine Receptor Type 3, Mouse | 350 | 0.25 | Functional ≤ 10μM |
| CCR3_HUMAN | P51677 | C-C Chemokine Receptor Type 3, Human | 6.1 | 0.32 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Chemokine receptors bind chemokines | |
| G alpha (i) signalling events |
