| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 2nd, 2008 | 33 | No |
Popular Name: Morphine-6-glucuronide Morphine-6-glucuronide
Find On: PubMed — Wikipedia — Google
CAS Number: 20290-10-2
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -0.73 | 0.81 | -74.29 | 5 | 10 | 0 | 153 | 461.467 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| OPRD-1-E | Delta Opioid Receptor (cluster #1 Of 3), Eukaryotic | Eukaryotes | 170 | 0.29 | Binding ≤ 10μM |
| OPRK-1-E | Kappa Opioid Receptor (cluster #1 Of 6), Eukaryotic | Eukaryotes | 4060 | 0.23 | Binding ≤ 10μM |
| OPRM-4-E | Mu-type Opioid Receptor (cluster #4 Of 4), Eukaryotic | Eukaryotes | 13 | 0.33 | Binding ≤ 10μM |
| OPRD-1-E | Delta Opioid Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 190 | 0.29 | Functional ≤ 10μM |
| OPRM-1-E | Mu Opioid Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 72 | 0.30 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| OPRD_HUMAN | P41143 | Delta Opioid Receptor, Human | 170 | 0.29 | Binding ≤ 1μM |
| OPRD_PIG | P79291 | Delta Opioid Receptor, Pig | 170 | 0.29 | Binding ≤ 1μM |
| OPRM_HUMAN | P35372 | Mu Opioid Receptor, Human | 12.9 | 0.33 | Binding ≤ 1μM |
| OPRD_PIG | P79291 | Delta Opioid Receptor, Pig | 170 | 0.29 | Binding ≤ 10μM |
| OPRD_HUMAN | P41143 | Delta Opioid Receptor, Human | 170 | 0.29 | Binding ≤ 10μM |
| OPRK_HUMAN | P41145 | Kappa Opioid Receptor, Human | 4060 | 0.23 | Binding ≤ 10μM |
| OPRK_CAVPO | P41144 | Kappa Opioid Receptor, Guinea Pig | 4060 | 0.23 | Binding ≤ 10μM |
| OPRM_HUMAN | P35372 | Mu Opioid Receptor, Human | 12.9 | 0.33 | Binding ≤ 10μM |
| OPRD_PIG | P79291 | Delta Opioid Receptor, Pig | 190 | 0.29 | Functional ≤ 10μM |
| OPRD_HUMAN | P41143 | Delta Opioid Receptor, Human | 190 | 0.29 | Functional ≤ 10μM |
| OPRM_MOUSE | P42866 | Mu Opioid Receptor, Mouse | 72.3 | 0.30 | Functional ≤ 10μM |
| OPRM_HUMAN | P35372 | Mu Opioid Receptor, Human | 72.3 | 0.30 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| G-protein activation | |
| Opioid Signalling | |
| Peptide ligand-binding receptors |
