| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 6th, 2004 | 18 | No |
Popular Name: Tolbutamide Tolbutamide
Find On: PubMed — Wikipedia — Google
CAS Numbers: 10238-21-8 , 473-41-6 , 64-77-7 , [64-77-7]
1-BUTYL-3-(4-METHYLBENZENESULFONYL)UREA
1-butyl-3-(4-methylphenyl)sulfonylurea
1-Butyl-3-(4-methylphenylsulfonyl)urea
1-Butyl-3-(p-methylphenylsulfonyl)urea
1-Butyl-3-(p-tolylsulfonyl)urea
1-Butyl-3-(para-tolylsulfonyl) urea
1-n-Butyl-3-(p-tolylsulfonyl)urea
1-p-Toluenesulfonyl-3-butylurea
3-(p-Tolyl-4-sulfonyl)-1-butylurea
3-(p-tolylsulfonyl)-1-butylurea
3-butyl-1-(4-methylbenzenesulfonyl)urea
3-[p-Tolyl-4-sulfonyl]-1-butylurea
473-41-6; D06177; Orinase diagnostic (TN); Tolbutamide sodium, sterile
64-77-7; CPD000058363; SAM002554936; Tolbutamide
64-77-7; D00380; Orinase (TN); Tolbutamide (JP16/USP/INN)
64-77-7; Prestwick_471; Tolbutamide
Berlin Chemie Brand of Tolbutamide
Berlin-Chemie Brand of Tolbutamide
CPD000058363; SAM002554936; Tolbutamide
N-(4-Methylbenzenesulfonyl)-N'-butylurea
N-(4-Methylphenylsulfonyl)-N'-butylurea
N-(Butylcarbamoyl)-4-methylbenzenesulfonamide
N-(p-Tolylsulfonyl)-N'-butylcarbamide
N-(p-tolylsulfonyl)-N'-n-butylurea
N-4-(Methylbenzolsulfonyl)-n-butylurea
N-4-Methylbenzolsulfonyl-N-butylurea
N-Butyl-N'-(4-methylphenylsulfonyl)urea
N-Butyl-N'-(p-tolylsulfonyl)urea
N-Butyl-N'-p-toluenesulfonylurea
N-Butyl-N'-toluene-p-sulfonylurea
Sterile (USP); Tolbutamide Sodium (FDA)
tolbutamida; tolbutamide; tolbutamidum
Urea, 1-butyl-3-(p-tolylsulfonyl)-
USP); Tolbutamide Sodium (FDA); Tolbutamide Sodium
Valdecasas Brand of Tolbutamide
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.17 | 1.02 | -55.2 | 1 | 5 | -1 | 82 | 269.346 | 6 | ↓ |
| Ref Reference (pH 7) | 2.17 | 0.59 | -9.68 | 2 | 5 | 0 | 79 | 270.354 | 6 | ↓ |
| Lo Low (pH 4.5-6) | 2.54 | 2.98 | -12.9 | 2 | 5 | 0 | 75 | 270.354 | 5 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| Melting_Point | 128-130? | Alfa-Aesar |
| Melting_Point | 128-130° | Alfa-Aesar |
| ALOGPS_SOLUBILITY | 2.02e-01 g/l | DrugBank-approved |
| purity | 9.500000000000000e+001 | Enamine Building Blocks Enamine Building Blocks |
| Purity | 95% | Fluorochem |
| therap | antidiabetic | MicroSource Spectrum |
| UniProt Database Links | CP2C9_HUMAN; CP2CP_MESAU; CP2CQ_MESAU; CP2CR_MESAU; CP2CS_MESAU | ChEBI |
| Patent Database Links | EP1088824; EP1136071; EP1258253; EP1354882; EP1391460; EP1452530; EP1479666; EP1493443; EP1500403; EP1514550; EP1533292; EP1553091; EP1611879; EP1616561; EP1634605; EP1669345; EP1671637; EP1743655; EP1785144; EP1813273; EP1829858; EP1832291; EP1832576; EP | ChEBI |
| PUBCHEM_SUBSTANCE_COMMENT | NCC_SAMPLE_SUPPLIER : LightBiologicals; NCC_SUPPLIER_STRUCTURE_ID : T-4213; NCC_SUPPLIER_SAMPLE_COMMENTS : WHITE POWDER | NIH Clinical Collection via PubChem |
| Therapy | Oral hypoglycemic agent; stimulates pancreatic islet cells to secrete insulin | SMDC Iconix |
| Target | Potassium Channel | Selleck Chemicals |
| Reactome Database Links | REACT_13607 | ChEBI |
| PUBCHEM_SUBSTANCE_COMMENT | SAMPLE_SUPPLIER: LightBiologicals; SUPPLIER_STRUCTURE_ID: T-4213; SUPPLIER_COMMENTS: WHITE POWDER | NIH Clinical Collection via PubChem |
| Description | Species |
|---|---|
| Xenobiotics |
