In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
October 6th, 2004 | 25 | No |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | -1.94 | -0.92 | -67.63 | 2 | 7 | -1 | 117 | 347.391 | 8 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
ACE-1-E | Angiotensin-converting Enzyme (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.50 | Binding ≤ 10μM |
ACE-1-E | Angiotensin-converting Enzyme (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2 | 0.49 | Binding ≤ 10μM |
ACE-1-E | Angiotensin-converting Enzyme (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2 | 0.49 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
ACE_RAT | P47820 | Angiotensin-converting Enzyme, Rat | 2.3 | 0.48 | Binding ≤ 1μM |
ACE_HUMAN | P12821 | Angiotensin-converting Enzyme, Human | 1.2 | 0.50 | Binding ≤ 1μM |
ACE_RAT | P47820 | Angiotensin-converting Enzyme, Rat | 2.3 | 0.48 | Binding ≤ 10μM |
ACE_HUMAN | P12821 | Angiotensin-converting Enzyme, Human | 1.2 | 0.50 | Binding ≤ 10μM |
Description | Species |
---|---|
Metabolism of Angiotensinogen to Angiotensins |