| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 26th, 2005 | 32 | Yes |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.28 | 10.55 | -17.52 | 0 | 8 | 0 | 94 | 458.584 | 10 | ↓ |
| Lo Low (pH 4.5-6) | 3.28 | 11.07 | -43.58 | 1 | 8 | 1 | 96 | 459.592 | 10 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PTAFR-1-E | Platelet Activating Factor Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 0 | 0.00 | Binding ≤ 10μM |
| Z50592-1-O | Oryctolagus Cuniculus (cluster #1 Of 8), Other | Other | 4 | 0.37 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PTAFR_HUMAN | P25105 | Platelet Activating Factor Receptor, Human | 0.38 | 0.41 | Binding ≤ 1μM |
| PTAFR_HUMAN | P25105 | Platelet Activating Factor Receptor, Human | 0.38 | 0.41 | Binding ≤ 10μM |
| Z50592 | Z50592 | Oryctolagus Cuniculus | 3.6 | 0.37 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Class A/1 (Rhodopsin-like receptors) | |
| G alpha (q) signalling events | |
| Interferon gamma signaling |
