UCSF

ZINC18825339

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
October 14th, 2008 32 No

Popular Name: (Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-N-(2-hydroxy-3-morpholinopropyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide (Z)-5-((5-Fluoro-2-oxoindolin-3-…

Find On: PubMed — Wikipedia — Google

CAS Number: 627908-92-3

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.40 1.85 -15.93 4 8 0 110 442.491 6 ↓

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
AAK1-1-E Adaptor-associated Kinase (cluster #1 Of 2), Eukaryotic Eukaryotes 66 0.31 Binding ≤ 10μM
AAPK1-1-E AMP-activated Protein Kinase, Alpha-1 Subunit (cluster #1 Of 1), Eukaryotic Eukaryotes 100 0.31 Binding ≤ 10μM
AAPK2-1-E AMP-activated Protein Kinase, Alpha-2 Subunit (cluster #1 Of 1), Eukaryotic Eukaryotes 290 0.29 Binding ≤ 10μM
ABL1-1-E Tyrosine-protein Kinase ABL (cluster #1 Of 1), Eukaryotic Eukaryotes 970 0.26 Binding ≤ 10μM
ACK1-1-E Tyrosine Kinase Non-receptor Protein 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 4900 0.23 Binding ≤ 10μM
ALK-1-E ALK Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic Eukaryotes 490 0.28 Binding ≤ 10μM
ANKK1-1-E Ankyrin Repeat And Protein Kinase Domain-containing Protein 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 160 0.30 Binding ≤ 10μM
AURKB-1-E Serine/threonine-protein Kinase Aurora-B (cluster #1 Of 2), Eukaryotic Eukaryotes 340 0.28 Binding ≤ 10μM
AURKC-1-E Serine/threonine-protein Kinase Aurora-C (cluster #1 Of 2), Eukaryotic Eukaryotes 810 0.27 Binding ≤ 10μM
BLK-1-E Tyrosine-protein Kinase BLK (cluster #1 Of 1), Eukaryotic Eukaryotes 750 0.27 Binding ≤ 10μM
BMP2K-1-E BMP-2-inducible Protein Kinase (cluster #1 Of 2), Eukaryotic Eukaryotes 27 0.33 Binding ≤ 10μM
BMPR2-1-E Bone Morphogenetic Protein Receptor Type-2 (cluster #1 Of 1), Eukaryotic Eukaryotes 200 0.29 Binding ≤ 10μM
BRSK1-1-E BR Serine/threonine-protein Kinase 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 5000 0.23 Binding ≤ 10μM
BRSK2-1-E BR Serine/threonine-protein Kinase 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 4100 0.24 Binding ≤ 10μM
CDK16-1-E Serine/threonine-protein Kinase PCTAIRE-1 (cluster #1 Of 1), Eukaryotic Eukaryotes 940 0.26 Binding ≤ 10μM
CDK7-1-E Cyclin-dependent Kinase 7 (cluster #1 Of 1), Eukaryotic Eukaryotes 930 0.26 Binding ≤ 10μM
CHK1-1-E Serine/threonine-protein Kinase Chk1 (cluster #1 Of 2), Eukaryotic Eukaryotes 1200 0.26 Binding ≤ 10μM
CLK1-1-E Dual Specificty Protein Kinase CLK1 (cluster #1 Of 2), Eukaryotic Eukaryotes 360 0.28 Binding ≤ 10μM
CLK2-1-E Dual Specificity Protein Kinase CLK2 (cluster #1 Of 2), Eukaryotic Eukaryotes 150 0.30 Binding ≤ 10μM
CLK4-1-E Dual Specificity Protein Kinase CLK4 (cluster #1 Of 2), Eukaryotic Eukaryotes 250 0.29 Binding ≤ 10μM
CSF1R-1-E Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic Eukaryotes 4 0.37 Binding ≤ 10μM
CSK21-1-E Casein Kinase II Alpha (cluster #1 Of 3), Eukaryotic Eukaryotes 97 0.31 Binding ≤ 10μM
CSK22-1-E Casein Kinase II Alpha (prime) (cluster #1 Of 2), Eukaryotic Eukaryotes 140 0.30 Binding ≤ 10μM
CTRO-1-E Citron Rho-interacting Kinase (cluster #1 Of 1), Eukaryotic Eukaryotes 94 0.31 Binding ≤ 10μM
DAPK1-1-E Death-associated Protein Kinase 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 270 0.29 Binding ≤ 10μM
DAPK2-1-E Death-associated Protein Kinase 2 (cluster #1 Of 2), Eukaryotic Eukaryotes 400 0.28 Binding ≤ 10μM
DAPK3-1-E Death-associated Protein Kinase 3 (cluster #1 Of 2), Eukaryotic Eukaryotes 560 0.27 Binding ≤ 10μM
DCLK1-1-E Serine/threonine-protein Kinase DCLK1 (cluster #1 Of 1), Eukaryotic Eukaryotes 550 0.27 Binding ≤ 10μM
DCLK3-1-E Serine/threonine-protein Kinase DCLK3 (cluster #1 Of 1), Eukaryotic Eukaryotes 240 0.29 Binding ≤ 10μM
DYR1B-1-E Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B (cluster #1 Of 1), Eukaryotic Eukaryotes 2600 0.24 Binding ≤ 10μM
E2AK2-1-E Interferon-induced, Double-stranded RNA-activated Protein Kinase (cluster #1 Of 1), Eukaryotic Eukaryotes 1300 0.26 Binding ≤ 10μM
E2AK4-1-E Eukaryotic Translation Initiation Factor 2-alpha Kinase 4 (cluster #1 Of 1), Eukaryotic Eukaryotes 470 0.28 Binding ≤ 10μM
EGFR-1-E Epidermal Growth Factor Receptor ErbB1 (cluster #1 Of 4), Eukaryotic Eukaryotes 9000 0.22 Binding ≤ 10μM
EPHA6-1-E Ephrin Type-A Receptor 6 (cluster #1 Of 1), Eukaryotic Eukaryotes 2000 0.25 Binding ≤ 10μM
FAK1-1-E Focal Adhesion Kinase 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 1200 0.26 Binding ≤ 10μM
FAK2-1-E Protein-tyrosine Kinase 2-beta (cluster #1 Of 1), Eukaryotic Eukaryotes 600 0.27 Binding ≤ 10μM
FER-1-E Tyrosine-protein Kinase FER (cluster #1 Of 1), Eukaryotic Eukaryotes 34 0.33 Binding ≤ 10μM
FGFR1-1-E Fibroblast Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 1900 0.25 Binding ≤ 10μM
FGFR2-1-E Fibroblast Growth Factor Receptor 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 790 0.27 Binding ≤ 10μM
FGFR3-1-E Fibroblast Growth Factor Receptor 3 (cluster #1 Of 1), Eukaryotic Eukaryotes 560 0.27 Binding ≤ 10μM
FGR-1-E Tyrosine-protein Kinase FGR (cluster #1 Of 2), Eukaryotic Eukaryotes 390 0.28 Binding ≤ 10μM
FLT3-1-E Tyrosine-protein Kinase Receptor FLT3 (cluster #1 Of 1), Eukaryotic Eukaryotes 6 0.36 Binding ≤ 10μM
FYN-1-E Tyrosine-protein Kinase FYN (cluster #1 Of 5), Eukaryotic Eukaryotes 2600 0.24 Binding ≤ 10μM
GAK-1-E Serine/threonine-protein Kinase GAK (cluster #1 Of 2), Eukaryotic Eukaryotes 44 0.32 Binding ≤ 10μM
HCK-1-E Tyrosine-protein Kinase HCK (cluster #1 Of 1), Eukaryotic Eukaryotes 2200 0.25 Binding ≤ 10μM
IKKE-1-E Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit (cluster #1 Of 1), Eukaryotic Eukaryotes 480 0.28 Binding ≤ 10μM
INSR-1-E Insulin Receptor (cluster #1 Of 1), Eukaryotic Eukaryotes 1200 0.26 Binding ≤ 10μM
INSRR-1-E Insulin Receptor-related Protein (cluster #1 Of 1), Eukaryotic Eukaryotes 2000 0.25 Binding ≤ 10μM
IRAK3-1-E Interleukin-1 Receptor-associated Kinase 3 (cluster #1 Of 1), Eukaryotic Eukaryotes 1900 0.25 Binding ≤ 10μM
ITK-1-E Tyrosine-protein Kinase ITK/TSK (cluster #1 Of 1), Eukaryotic Eukaryotes 190 0.29 Binding ≤ 10μM
JAK1-1-E Tyrosine-protein Kinase JAK1 (cluster #1 Of 1), Eukaryotic Eukaryotes 97 0.31 Binding ≤ 10μM
JAK2-1-E Tyrosine-protein Kinase JAK2 (cluster #1 Of 1), Eukaryotic Eukaryotes 1600 0.25 Binding ≤ 10μM
JAK3-1-E Tyrosine-protein Kinase JAK3 (cluster #1 Of 2), Eukaryotic Eukaryotes 580 0.27 Binding ≤ 10μM
KC1AL-1-E Casein Kinase I Isoform Alpha-like (cluster #1 Of 1), Eukaryotic Eukaryotes 1500 0.25 Binding ≤ 10μM
KC1D-1-E Casein Kinase I Delta (cluster #1 Of 1), Eukaryotic Eukaryotes 260 0.29 Binding ≤ 10μM
KC1E-1-E Casein Kinase I Epsilon (cluster #1 Of 2), Eukaryotic Eukaryotes 340 0.28 Binding ≤ 10μM
KC1G1-1-E Casein Kinase I Gamma 1 (cluster #1 Of 2), Eukaryotic Eukaryotes 1000 0.26 Binding ≤ 10μM
KC1G2-1-E Casein Kinase I Gamma 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 790 0.27 Binding ≤ 10μM
KC1G3-1-E Casein Kinase I Isoform Gamma-3 (cluster #1 Of 1), Eukaryotic Eukaryotes 570 0.27 Binding ≤ 10μM
KCC1A-1-E CaM Kinase I Alpha (cluster #1 Of 2), Eukaryotic Eukaryotes 3300 0.24 Binding ≤ 10μM
KCC1D-1-E CaM Kinase I Delta (cluster #1 Of 2), Eukaryotic Eukaryotes 970 0.26 Binding ≤ 10μM
KCC1G-1-E CaM Kinase I Gamma (cluster #1 Of 2), Eukaryotic Eukaryotes 940 0.26 Binding ≤ 10μM
KCC2A-1-E CaM Kinase II Alpha (cluster #1 Of 1), Eukaryotic Eukaryotes 350 0.28 Binding ≤ 10μM
KCC2B-1-E CaM Kinase II Beta (cluster #1 Of 1), Eukaryotic Eukaryotes 2300 0.25 Binding ≤ 10μM
KCC2D-1-E CaM Kinase II Delta (cluster #1 Of 1), Eukaryotic Eukaryotes 760 0.27 Binding ≤ 10μM
KCC2G-1-E CaM Kinase II Gamma (cluster #1 Of 1), Eukaryotic Eukaryotes 1100 0.26 Binding ≤ 10μM
KCC4-1-E CaM Kinase IV (cluster #1 Of 1), Eukaryotic Eukaryotes 2700 0.24 Binding ≤ 10μM
KIT-1-E Stem Cell Growth Factor Receptor (cluster #1 Of 1), Eukaryotic Eukaryotes 340 0.28 Binding ≤ 10μM
KKCC1-1-E CaM-kinase Kinase Alpha (cluster #1 Of 1), Eukaryotic Eukaryotes 850 0.27 Binding ≤ 10μM
KKCC2-1-E CaM-kinase Kinase Beta (cluster #1 Of 2), Eukaryotic Eukaryotes 2500 0.25 Binding ≤ 10μM
KPCD1-1-E Protein Kinase C Mu (cluster #1 Of 3), Eukaryotic Eukaryotes 2400 0.25 Binding ≤ 10μM
KPCD2-1-E Serine/threonine-protein Kinase D2 (cluster #1 Of 1), Eukaryotic Eukaryotes 3700 0.24 Binding ≤ 10μM
KPCD3-1-E Protein Kinase C Nu (cluster #1 Of 3), Eukaryotic Eukaryotes 2700 0.24 Binding ≤ 10μM
KPCT-1-E Protein Kinase C Theta (cluster #1 Of 3), Eukaryotic Eukaryotes 7200 0.22 Binding ≤ 10μM
KS6A1-1-E Ribosomal Protein S6 Kinase Alpha 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 5800 0.23 Binding ≤ 10μM
KS6A2-1-E Ribosomal Protein S6 Kinase Alpha 2 (cluster #1 Of 2), Eukaryotic Eukaryotes 9600 0.22 Binding ≤ 10μM
KS6A3-1-E Ribosomal Protein S6 Kinase Alpha 3 (cluster #1 Of 1), Eukaryotic Eukaryotes 2100 0.25 Binding ≤ 10μM
KS6A4-1-E Ribosomal Protein S6 Kinase Alpha 4 (cluster #1 Of 1), Eukaryotic Eukaryotes 2000 0.25 Binding ≤ 10μM
KS6A5-1-E Ribosomal Protein S6 Kinase Alpha 5 (cluster #1 Of 3), Eukaryotic Eukaryotes 1500 0.25 Binding ≤ 10μM
KS6A6-1-E Ribosomal Protein S6 Kinase Alpha 6 (cluster #1 Of 1), Eukaryotic Eukaryotes 3100 0.24 Binding ≤ 10μM
LATS1-1-E Serine/threonine-protein Kinase LATS1 (cluster #1 Of 1), Eukaryotic Eukaryotes 850 0.27 Binding ≤ 10μM
LATS2-1-E Serine/threonine-protein Kinase LATS2 (cluster #1 Of 1), Eukaryotic Eukaryotes 430 0.28 Binding ≤ 10μM
LCK-1-E Tyrosine-protein Kinase LCK (cluster #1 Of 4), Eukaryotic Eukaryotes 2300 0.25 Binding ≤ 10μM
LTK-1-E Leukocyte Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic Eukaryotes 4200 0.24 Binding ≤ 10μM
LYN-1-E Tyrosine-protein Kinase Lyn (cluster #1 Of 1), Eukaryotic Eukaryotes 810 0.27 Binding ≤ 10μM
M3K11-1-E Mitogen-activated Protein Kinase Kinase Kinase 11 (cluster #1 Of 1), Eukaryotic Eukaryotes 1700 0.25 Binding ≤ 10μM
M3K9-1-E Mitogen-activated Protein Kinase Kinase Kinase 9 (cluster #1 Of 1), Eukaryotic Eukaryotes 2600 0.24 Binding ≤ 10μM
M4K1-1-E Mitogen-activated Protein Kinase Kinase Kinase Kinase 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 15 0.34 Binding ≤ 10μM
M4K3-1-E Mitogen-activated Protein Kinase Kinase Kinase Kinase 3 (cluster #1 Of 1), Eukaryotic Eukaryotes 210 0.29 Binding ≤ 10μM
M4K4-1-E Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (cluster #1 Of 2), Eukaryotic Eukaryotes 260 0.29 Binding ≤ 10μM
M4K5-1-E Mitogen-activated Protein Kinase Kinase Kinase Kinase 5 (cluster #1 Of 1), Eukaryotic Eukaryotes 300 0.29 Binding ≤ 10μM
MARK1-1-E Serine/threonine-protein Kinase MARK1 (cluster #1 Of 1), Eukaryotic Eukaryotes 1500 0.25 Binding ≤ 10μM
MARK2-1-E MAP/microtubule Affinity-regulating Kinase 2 (cluster #1 Of 2), Eukaryotic Eukaryotes 440 0.28 Binding ≤ 10μM
MARK3-1-E Serine/threonine-protein Kinase C-TAK1 (cluster #1 Of 1), Eukaryotic Eukaryotes 1100 0.26 Binding ≤ 10μM
MARK4-1-E MAP/microtubule Affinity-regulating Kinase 4 (cluster #1 Of 1), Eukaryotic Eukaryotes 2000 0.25 Binding ≤ 10μM
MELK-1-E Maternal Embryonic Leucine Zipper Kinase (cluster #1 Of 1), Eukaryotic Eukaryotes 340 0.28 Binding ≤ 10μM
MERTK-1-E Proto-oncogene Tyrosine-protein Kinase MER (cluster #1 Of 1), Eukaryotic Eukaryotes 66 0.31 Binding ≤ 10μM
MKNK2-1-E MAP Kinase Signal-integrating Kinase 2 (cluster #1 Of 2), Eukaryotic Eukaryotes 5500 0.23 Binding ≤ 10μM
MP2K1-1-E Dual Specificity Mitogen-activated Protein Kinase Kinase 1 (cluster #1 Of 4), Eukaryotic Eukaryotes 77 0.31 Binding ≤ 10μM
MP2K2-1-E Dual Specificity Mitogen-activated Protein Kinase Kinase 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 120 0.30 Binding ≤ 10μM
MP2K4-1-E Dual Specificity Mitogen-activated Protein Kinase Kinase 4 (cluster #1 Of 1), Eukaryotic Eukaryotes 1400 0.26 Binding ≤ 10μM
MP2K6-1-E Dual Specificity Mitogen-activated Protein Kinase Kinase 6 (cluster #1 Of 1), Eukaryotic Eukaryotes 5500 0.23 Binding ≤ 10μM
MST4-1-E Serine/threonine-protein Kinase MST4 (cluster #1 Of 1), Eukaryotic Eukaryotes 330 0.28 Binding ≤ 10μM
MUSK-1-E Muscle, Skeletal Receptor Tyrosine Protein Kinase (cluster #1 Of 1), Eukaryotic Eukaryotes 100 0.31 Binding ≤ 10μM
MYLK-1-E Myosin Light Chain Kinase, Smooth Muscle (cluster #1 Of 1), Eukaryotic Eukaryotes 360 0.28 Binding ≤ 10μM
MYLK2-1-E Myosin Light Chain Kinase 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 190 0.29 Binding ≤ 10μM
MYLK4-1-E Myosin Light Chain Kinase Family Member 4 (cluster #1 Of 1), Eukaryotic Eukaryotes 32 0.33 Binding ≤ 10μM
NEK2-1-E Serine/threonine-protein Kinase NEK2 (cluster #1 Of 1), Eukaryotic Eukaryotes 1100 0.26 Binding ≤ 10μM
NEK7-1-E Serine/threonine-protein Kinase NEK7 (cluster #1 Of 1), Eukaryotic Eukaryotes 3200 0.24 Binding ≤ 10μM
NTRK1-1-E Nerve Growth Factor Receptor Trk-A (cluster #1 Of 1), Eukaryotic Eukaryotes 480 0.28 Binding ≤ 10μM
NTRK2-1-E Neurotrophic Tyrosine Kinase Receptor Type 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 990 0.26 Binding ≤ 10μM
NTRK3-1-E NT-3 Growth Factor Receptor (cluster #1 Of 1), Eukaryotic Eukaryotes 220 0.29 Binding ≤ 10μM
NUAK1-1-E NUAK Family SNF1-like Kinase 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 460 0.28 Binding ≤ 10μM
NUAK2-1-E NUAK Family SNF1-like Kinase 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 400 0.28 Binding ≤ 10μM
PAK3-1-E Serine/threonine-protein Kinase PAK 3 (cluster #1 Of 1), Eukaryotic Eukaryotes 190 0.29 Binding ≤ 10μM
PDPK1-1-E 3-phosphoinositide Dependent Protein Kinase-1 (cluster #1 Of 2), Eukaryotic Eukaryotes 2600 0.24 Binding ≤ 10μM
PGFRA-1-E Platelet-derived Growth Factor Receptor Alpha (cluster #1 Of 2), Eukaryotic Eukaryotes 1 0.39 Binding ≤ 10μM
PGFRB-1-E Platelet-derived Growth Factor Receptor Beta (cluster #1 Of 1), Eukaryotic Eukaryotes 0 0.00 Binding ≤ 10μM
PHKG1-1-E Phosphorylase Kinase Gamma Subunit 1 (cluster #1 Of 2), Eukaryotic Eukaryotes 83 0.31 Binding ≤ 10μM
PHKG2-1-E Phosphorylase Kinase Gamma Subunit 2 (cluster #1 Of 2), Eukaryotic Eukaryotes 100 0.31 Binding ≤ 10μM
PI42B-1-E Phosphatidylinositol-5-phosphate 4-kinase Type-2 Beta (cluster #1 Of 1), Eukaryotic Eukaryotes 260 0.29 Binding ≤ 10μM
PI51A-1-E Phosphatidylinositol-4-phosphate 5-kinase Type-1 Alpha (cluster #1 Of 1), Eukaryotic Eukaryotes 130 0.30 Binding ≤ 10μM
PIM3-1-E Serine/threonine-protein Kinase PIM3 (cluster #1 Of 1), Eukaryotic Eukaryotes 2400 0.25 Binding ≤ 10μM
PKN1-1-E Protein Kinase N1 (cluster #1 Of 1), Eukaryotic Eukaryotes 1900 0.25 Binding ≤ 10μM
PKN2-1-E Protein Kinase N2 (cluster #1 Of 1), Eukaryotic Eukaryotes 3800 0.24 Binding ≤ 10μM
PLK4-1-E Serine/threonine-protein Kinase PLK4 (cluster #1 Of 1), Eukaryotic Eukaryotes 180 0.30 Binding ≤ 10μM
RET-1-E Tyrosine-protein Kinase Receptor RET (cluster #1 Of 1), Eukaryotic Eukaryotes 37 0.33 Binding ≤ 10μM
RIOK1-1-E Serine/threonine-protein Kinase RIO1 (cluster #1 Of 1), Eukaryotic Eukaryotes 590 0.27 Binding ≤ 10μM
RIOK3-1-E Serine/threonine-protein Kinase RIO3 (cluster #1 Of 1), Eukaryotic Eukaryotes 9700 0.22 Binding ≤ 10μM
RIPK1-1-E Receptor-interacting Serine/threonine-protein Kinase 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 1200 0.26 Binding ≤ 10μM
SIK1-1-E Serine/threonine-protein Kinase SIK1 (cluster #1 Of 1), Eukaryotic Eukaryotes 2700 0.24 Binding ≤ 10μM
SIK2-1-E Serine/threonine-protein Kinase SIK2 (cluster #1 Of 1), Eukaryotic Eukaryotes 750 0.27 Binding ≤ 10μM
SLK-1-E Serine/threonine-protein Kinase 2 (cluster #1 Of 2), Eukaryotic Eukaryotes 460 0.28 Binding ≤ 10μM
SRC-1-E Tyrosine-protein Kinase SRC (cluster #1 Of 3), Eukaryotic Eukaryotes 4900 0.23 Binding ≤ 10μM
SRMS-1-E Tyrosine-protein Kinase Srms (cluster #1 Of 1), Eukaryotic Eukaryotes 62 0.32 Binding ≤ 10μM
SRPK1-1-E Serine/threonine-protein Kinase SRPK1 (cluster #1 Of 1), Eukaryotic Eukaryotes 4000 0.24 Binding ≤ 10μM
SRPK2-1-E Serine/threonine-protein Kinase SRPK2 (cluster #1 Of 1), Eukaryotic Eukaryotes 200 0.29 Binding ≤ 10μM
ST17A-1-E Serine/threonine-protein Kinase 17A (cluster #1 Of 2), Eukaryotic Eukaryotes 24 0.33 Binding ≤ 10μM
ST17B-1-E Serine/threonine-protein Kinase 17B (cluster #1 Of 1), Eukaryotic Eukaryotes 320 0.28 Binding ≤ 10μM
ST38L-1-E Serine/threonine-protein Kinase 38-like (cluster #1 Of 2), Eukaryotic Eukaryotes 2000 0.25 Binding ≤ 10μM
STK10-1-E Serine/threonine-protein Kinase 10 (cluster #1 Of 1), Eukaryotic Eukaryotes 230 0.29 Binding ≤ 10μM
STK11-1-E Serine/threonine-protein Kinase 11 (cluster #1 Of 1), Eukaryotic Eukaryotes 360 0.28 Binding ≤ 10μM
STK16-1-E Serine/threonine-protein Kinase 16 (cluster #1 Of 1), Eukaryotic Eukaryotes 730 0.27 Binding ≤ 10μM
STK24-1-E Serine/threonine-protein Kinase 24 (cluster #1 Of 1), Eukaryotic Eukaryotes 100 0.31 Binding ≤ 10μM
STK25-1-E Serine/threonine-protein Kinase 25 (cluster #1 Of 1), Eukaryotic Eukaryotes 360 0.28 Binding ≤ 10μM
STK3-1-E Serine/threonine-protein Kinase MST2 (cluster #1 Of 2), Eukaryotic Eukaryotes 65 0.31 Binding ≤ 10μM
STK33-1-E Serine/threonine-protein Kinase 33 (cluster #1 Of 1), Eukaryotic Eukaryotes 130 0.30 Binding ≤ 10μM
STK4-1-E Serine/threonine-protein Kinase MST1 (cluster #1 Of 2), Eukaryotic Eukaryotes 130 0.30 Binding ≤ 10μM
TLK1-1-E Serine/threonine-protein Kinase Tousled-like 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 630 0.27 Binding ≤ 10μM
TLK2-1-E Serine/threonine-protein Kinase Tousled-like 2 (cluster #1 Of 1), Eukaryotic Eukaryotes 270 0.29 Binding ≤ 10μM
TNIK-1-E TRAF2- And NCK-interacting Kinase (cluster #1 Of 2), Eukaryotic Eukaryotes 90 0.31 Binding ≤ 10μM
TNK1-1-E Non-receptor Tyrosine-protein Kinase TNK1 (cluster #1 Of 1), Eukaryotic Eukaryotes 1500 0.25 Binding ≤ 10μM
TTK-1-E Dual Specificity Protein Kinase TTK (cluster #1 Of 2), Eukaryotic Eukaryotes 180 0.30 Binding ≤ 10μM
TYK2-1-E Tyrosine-protein Kinase TYK2 (cluster #1 Of 1), Eukaryotic Eukaryotes 5100 0.23 Binding ≤ 10μM
TYRO3-1-E Tyrosine-protein Kinase Receptor TYRO3 (cluster #1 Of 1), Eukaryotic Eukaryotes 2400 0.25 Binding ≤ 10μM
UFO-1-E Tyrosine-protein Kinase Receptor UFO (cluster #1 Of 1), Eukaryotic Eukaryotes 84 0.31 Binding ≤ 10μM
VGFR1-1-E Vascular Endothelial Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic Eukaryotes 5 0.36 Binding ≤ 10μM
VGFR2-1-E Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic Eukaryotes 2 0.38 Binding ≤ 10μM
VGFR3-1-E Vascular Endothelial Growth Factor Receptor 3 (cluster #1 Of 2), Eukaryotic Eukaryotes 50 0.32 Binding ≤ 10μM
WEE1-1-E Serine/threonine-protein Kinase WEE1 (cluster #1 Of 1), Eukaryotic Eukaryotes 3000 0.24 Binding ≤ 10μM
YES-1-E Tyrosine-protein Kinase YES (cluster #1 Of 1), Eukaryotic Eukaryotes 260 0.29 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
AAK1_HUMAN Q2M2I8 Adaptor-associated Kinase, Human 66 0.31 Binding ≤ 1μM
ALK_HUMAN Q9UM73 ALK Tyrosine Kinase Receptor, Human 490 0.28 Binding ≤ 1μM
AAPK1_HUMAN Q13131 AMP-activated Protein Kinase, Alpha-1 Subunit, Human 100 0.31 Binding ≤ 1μM
AAPK2_HUMAN P54646 AMP-activated Protein Kinase, Alpha-2 Subunit, Human 290 0.29 Binding ≤ 1μM
ANKK1_HUMAN Q8NFD2 Ankyrin Repeat And Protein Kinase Domain-containing Protein 1, Human 160 0.30 Binding ≤ 1μM
BMP2K_HUMAN Q9NSY1 BMP-2-inducible Protein Kinase, Human 27 0.33 Binding ≤ 1μM
BMPR2_HUMAN Q13873 Bone Morphogenetic Protein Receptor Type-2, Human 200 0.29 Binding ≤ 1μM
KCC1D_HUMAN Q8IU85 CaM Kinase I Delta, Human 970 0.26 Binding ≤ 1μM
KCC1G_HUMAN Q96NX5 CaM Kinase I Gamma, Human 940 0.26 Binding ≤ 1μM
KCC2A_HUMAN Q9UQM7 CaM Kinase II Alpha, Human 350 0.28 Binding ≤ 1μM
KCC2D_HUMAN Q13557 CaM Kinase II Delta, Human 760 0.27 Binding ≤ 1μM
KKCC1_HUMAN Q8N5S9 CaM-kinase Kinase Alpha, Human 850 0.27 Binding ≤ 1μM
KC1D_HUMAN P48730 Casein Kinase I Delta, Human 260 0.29 Binding ≤ 1μM
KC1E_HUMAN P49674 Casein Kinase I Epsilon, Human 340 0.28 Binding ≤ 1μM
KC1G1_HUMAN Q9HCP0 Casein Kinase I Gamma 1, Human 1000 0.26 Binding ≤ 1μM
KC1G2_HUMAN P78368 Casein Kinase I Gamma 2, Human 790 0.27 Binding ≤ 1μM
KC1G3_HUMAN Q9Y6M4 Casein Kinase I Isoform Gamma-3, Human 570 0.27 Binding ≤ 1μM
CSK21_HUMAN P68400 Casein Kinase II Alpha, Human 97 0.31 Binding ≤ 1μM
CSK22_HUMAN P19784 Casein Kinase II Alpha (prime), Human 140 0.30 Binding ≤ 1μM
CTRO_HUMAN O14578 Citron Rho-interacting Kinase, Human 94 0.31 Binding ≤ 1μM
CDK7_HUMAN P50613 Cyclin-dependent Kinase 7, Human 930 0.26 Binding ≤ 1μM
DAPK1_HUMAN P53355 Death-associated Protein Kinase 1, Human 270 0.29 Binding ≤ 1μM
DAPK2_HUMAN Q9UIK4 Death-associated Protein Kinase 2, Human 400 0.28 Binding ≤ 1μM
DAPK3_HUMAN O43293 Death-associated Protein Kinase 3, Human 170 0.30 Binding ≤ 1μM
MP2K1_HUMAN Q02750 Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human 77 0.31 Binding ≤ 1μM
MP2K2_HUMAN P36507 Dual Specificity Mitogen-activated Protein Kinase Kinase 2, Human 120 0.30 Binding ≤ 1μM
CLK2_HUMAN P49760 Dual Specificity Protein Kinase CLK2, Human 150 0.30 Binding ≤ 1μM
CLK4_HUMAN Q9HAZ1 Dual Specificity Protein Kinase CLK4, Human 250 0.29 Binding ≤ 1μM
TTK_HUMAN P33981 Dual Specificity Protein Kinase TTK, Human 180 0.30 Binding ≤ 1μM
CLK1_HUMAN P49759 Dual Specificty Protein Kinase CLK1, Human 360 0.28 Binding ≤ 1μM
E2AK4_HUMAN Q9P2K8 Eukaryotic Translation Initiation Factor 2-alpha Kinase 4, Human 470 0.28 Binding ≤ 1μM
FGFR2_HUMAN P21802 Fibroblast Growth Factor Receptor 2, Human 790 0.27 Binding ≤ 1μM
FGFR3_HUMAN P22607 Fibroblast Growth Factor Receptor 3, Human 380 0.28 Binding ≤ 1μM
IKKE_HUMAN Q14164 Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit, Human 480 0.28 Binding ≤ 1μM
CSF1R_HUMAN P07333 Macrophage Colony Stimulating Factor Receptor, Human 3.6 0.37 Binding ≤ 1μM
MARK2_HUMAN Q7KZI7 MAP/microtubule Affinity-regulating Kinase 2, Human 440 0.28 Binding ≤ 1μM
MELK_HUMAN Q14680 Maternal Embryonic Leucine Zipper Kinase, Human 340 0.28 Binding ≤ 1μM
M4K1_HUMAN Q92918 Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, Human 15 0.34 Binding ≤ 1μM
M4K3_HUMAN Q8IVH8 Mitogen-activated Protein Kinase Kinase Kinase Kinase 3, Human 210 0.29 Binding ≤ 1μM
M4K4_HUMAN O95819 Mitogen-activated Protein Kinase Kinase Kinase Kinase 4, Human 260 0.29 Binding ≤ 1μM
M4K5_HUMAN Q9Y4K4 Mitogen-activated Protein Kinase Kinase Kinase Kinase 5, Human 300 0.29 Binding ≤ 1μM
MUSK_HUMAN O15146 Muscle, Skeletal Receptor Tyrosine Protein Kinase, Human 100 0.31 Binding ≤ 1μM
MYLK2_HUMAN Q9H1R3 Myosin Light Chain Kinase 2, Human 190 0.29 Binding ≤ 1μM
MYLK4_HUMAN Q86YV6 Myosin Light Chain Kinase Family Member 4, Human 32 0.33 Binding ≤ 1μM
MYLK_CHICK P11799 Myosin Light Chain Kinase, Smooth Muscle, Chick 42 0.32 Binding ≤ 1μM
MYLK_HUMAN Q15746 Myosin Light Chain Kinase, Smooth Muscle, Human 360 0.28 Binding ≤ 1μM
NTRK1_HUMAN P04629 Nerve Growth Factor Receptor Trk-A, Human 480 0.28 Binding ≤ 1μM
NTRK2_HUMAN Q16620 Neurotrophic Tyrosine Kinase Receptor Type 2, Human 990 0.26 Binding ≤ 1μM
NTRK3_HUMAN Q16288 NT-3 Growth Factor Receptor, Human 220 0.29 Binding ≤ 1μM
NUAK1_HUMAN O60285 NUAK Family SNF1-like Kinase 1, Human 460 0.28 Binding ≤ 1μM
NUAK2_HUMAN Q9H093 NUAK Family SNF1-like Kinase 2, Human 400 0.28 Binding ≤ 1μM
PI51A_HUMAN Q99755 Phosphatidylinositol-4-phosphate 5-kinase Type-1 Alpha, Human 130 0.30 Binding ≤ 1μM
PI42B_HUMAN P78356 Phosphatidylinositol-5-phosphate 4-kinase Type-2 Beta, Human 260 0.29 Binding ≤ 1μM
PHKG1_HUMAN Q16816 Phosphorylase Kinase Gamma Subunit 1, Human 83 0.31 Binding ≤ 1μM
PHKG2_HUMAN P15735 Phosphorylase Kinase Gamma Subunit 2, Human 100 0.31 Binding ≤ 1μM
PGFRA_HUMAN P16234 Platelet-derived Growth Factor Receptor Alpha, Human 1.1 0.39 Binding ≤ 1μM
PGFRB_HUMAN P09619 Platelet-derived Growth Factor Receptor Beta, Human 0.29 0.42 Binding ≤ 1μM
FAK2_HUMAN Q14289 Protein Tyrosine Kinase 2 Beta, Human 600 0.27 Binding ≤ 1μM
MERTK_HUMAN Q12866 Proto-oncogene Tyrosine-protein Kinase MER, Human 66 0.31 Binding ≤ 1μM
KS6A1_HUMAN Q15418 Ribosomal Protein S6 Kinase Alpha 1, Human 180 0.30 Binding ≤ 1μM
KS6A2_HUMAN Q15349 Ribosomal Protein S6 Kinase Alpha 2, Human 260 0.29 Binding ≤ 1μM
KS6A4_HUMAN O75676 Ribosomal Protein S6 Kinase Alpha 4, Human 200 0.29 Binding ≤ 1μM
KS6A5_HUMAN O75582 Ribosomal Protein S6 Kinase Alpha 5, Human 150 0.30 Binding ≤ 1μM
STK10_HUMAN O94804 Serine/threonine-protein Kinase 10, Human 230 0.29 Binding ≤ 1μM
STK11_HUMAN Q15831 Serine/threonine-protein Kinase 11, Human 360 0.28 Binding ≤ 1μM
STK16_HUMAN O75716 Serine/threonine-protein Kinase 16, Human 730 0.27 Binding ≤ 1μM
ST17A_HUMAN Q9UEE5 Serine/threonine-protein Kinase 17A, Human 24 0.33 Binding ≤ 1μM
ST17B_HUMAN O94768 Serine/threonine-protein Kinase 17B, Human 320 0.28 Binding ≤ 1μM
SLK_HUMAN Q9H2G2 Serine/threonine-protein Kinase 2, Human 460 0.28 Binding ≤ 1μM
STK24_HUMAN Q9Y6E0 Serine/threonine-protein Kinase 24, Human 100 0.31 Binding ≤ 1μM
STK25_HUMAN O00506 Serine/threonine-protein Kinase 25, Human 360 0.28 Binding ≤ 1μM
STK33_HUMAN Q9BYT3 Serine/threonine-protein Kinase 33, Human 130 0.30 Binding ≤ 1μM
AURKB_HUMAN Q96GD4 Serine/threonine-protein Kinase Aurora-B, Human 340 0.28 Binding ≤ 1μM
AURKC_HUMAN Q9UQB9 Serine/threonine-protein Kinase Aurora-C, Human 810 0.27 Binding ≤ 1μM
DCLK1_HUMAN O15075 Serine/threonine-protein Kinase DCLK1, Human 550 0.27 Binding ≤ 1μM
DCLK3_HUMAN Q9C098 Serine/threonine-protein Kinase DCLK3, Human 240 0.29 Binding ≤ 1μM
GAK_HUMAN O14976 Serine/threonine-protein Kinase GAK, Human 44 0.32 Binding ≤ 1μM
LATS1_HUMAN O95835 Serine/threonine-protein Kinase LATS1, Human 850 0.27 Binding ≤ 1μM
LATS2_HUMAN Q9NRM7 Serine/threonine-protein Kinase LATS2, Human 430 0.28 Binding ≤ 1μM
STK4_HUMAN Q13043 Serine/threonine-protein Kinase MST1, Human 130 0.30 Binding ≤ 1μM
STK3_HUMAN Q13188 Serine/threonine-protein Kinase MST2, Human 65 0.31 Binding ≤ 1μM
MST4_HUMAN Q9P289 Serine/threonine-protein Kinase MST4, Human 330 0.28 Binding ≤ 1μM
PAK3_HUMAN O75914 Serine/threonine-protein Kinase PAK 3, Human 190 0.29 Binding ≤ 1μM
CDK16_HUMAN Q00536 Serine/threonine-protein Kinase PCTAIRE-1, Human 940 0.26 Binding ≤ 1μM
PLK4_HUMAN O00444 Serine/threonine-protein Kinase PLK4, Human 180 0.30 Binding ≤ 1μM
RIOK1_HUMAN Q9BRS2 Serine/threonine-protein Kinase RIO1, Human 590 0.27 Binding ≤ 1μM
SIK2_HUMAN Q9H0K1 Serine/threonine-protein Kinase SIK2, Human 750 0.27 Binding ≤ 1μM
SRPK2_HUMAN P78362 Serine/threonine-protein Kinase SRPK2, Human 200 0.29 Binding ≤ 1μM
TLK1_HUMAN Q9UKI8 Serine/threonine-protein Kinase Tousled-like 1, Human 630 0.27 Binding ≤ 1μM
TLK2_HUMAN Q86UE8 Serine/threonine-protein Kinase Tousled-like 2, Human 270 0.29 Binding ≤ 1μM
KIT_HUMAN P10721 Stem Cell Growth Factor Receptor, Human 0.25 0.42 Binding ≤ 1μM
TNIK_HUMAN Q9UKE5 TRAF2- And NCK-interacting Kinase, Human 90 0.31 Binding ≤ 1μM
ABL1_HUMAN P00519 Tyrosine-protein Kinase ABL, Human 260 0.29 Binding ≤ 1μM
BLK_HUMAN P51451 Tyrosine-protein Kinase BLK, Human 750 0.27 Binding ≤ 1μM
FER_HUMAN P16591 Tyrosine-protein Kinase FER, Human 34 0.33 Binding ≤ 1μM
FGR_HUMAN P09769 Tyrosine-protein Kinase FGR, Human 390 0.28 Binding ≤ 1μM
ITK_HUMAN Q08881 Tyrosine-protein Kinase ITK/TSK, Human 190 0.29 Binding ≤ 1μM
JAK1_HUMAN P23458 Tyrosine-protein Kinase JAK1, Human 97 0.31 Binding ≤ 1μM
JAK3_HUMAN P52333 Tyrosine-protein Kinase JAK3, Human 580 0.27 Binding ≤ 1μM
LYN_HUMAN P07948 Tyrosine-protein Kinase Lyn, Human 810 0.27 Binding ≤ 1μM
FLT3_HUMAN P36888 Tyrosine-protein Kinase Receptor FLT3, Human 0.54 0.41 Binding ≤ 1μM
RET_HUMAN P07949 Tyrosine-protein Kinase Receptor RET, Human 24 0.33 Binding ≤ 1μM
UFO_HUMAN P30530 Tyrosine-protein Kinase Receptor UFO, Human 84 0.31 Binding ≤ 1μM
SRMS_HUMAN Q9H3Y6 Tyrosine-protein Kinase Srms, Human 62 0.32 Binding ≤ 1μM
YES_HUMAN P07947 Tyrosine-protein Kinase YES, Human 260 0.29 Binding ≤ 1μM
VGFR1_HUMAN P17948 Vascular Endothelial Growth Factor Receptor 1, Human 4.7 0.36 Binding ≤ 1μM
VGFR2_HUMAN P35968 Vascular Endothelial Growth Factor Receptor 2, Human 2.3 0.38 Binding ≤ 1μM
VGFR3_HUMAN P35916 Vascular Endothelial Growth Factor Receptor 3, Human 50 0.32 Binding ≤ 1μM
PDPK1_HUMAN O15530 3-phosphoinositide Dependent Protein Kinase-1, Human 2600 0.24 Binding ≤ 10μM
AAK1_HUMAN Q2M2I8 Adaptor-associated Kinase, Human 66 0.31 Binding ≤ 10μM
ALK_HUMAN Q9UM73 ALK Tyrosine Kinase Receptor, Human 490 0.28 Binding ≤ 10μM
AAPK1_HUMAN Q13131 AMP-activated Protein Kinase, Alpha-1 Subunit, Human 100 0.31 Binding ≤ 10μM
AAPK2_HUMAN P54646 AMP-activated Protein Kinase, Alpha-2 Subunit, Human 290 0.29 Binding ≤ 10μM
ANKK1_HUMAN Q8NFD2 Ankyrin Repeat And Protein Kinase Domain-containing Protein 1, Human 160 0.30 Binding ≤ 10μM
BMP2K_HUMAN Q9NSY1 BMP-2-inducible Protein Kinase, Human 27 0.33 Binding ≤ 10μM
BMPR2_HUMAN Q13873 Bone Morphogenetic Protein Receptor Type-2, Human 200 0.29 Binding ≤ 10μM
BRSK1_HUMAN Q8TDC3 BR Serine/threonine-protein Kinase 1, Human 5000 0.23 Binding ≤ 10μM
BRSK2_HUMAN Q8IWQ3 BR Serine/threonine-protein Kinase 2, Human 4100 0.24 Binding ≤ 10μM
KCC1A_HUMAN Q14012 CaM Kinase I Alpha, Human 3300 0.24 Binding ≤ 10μM
KCC1D_HUMAN Q8IU85 CaM Kinase I Delta, Human 970 0.26 Binding ≤ 10μM
KCC1G_HUMAN Q96NX5 CaM Kinase I Gamma, Human 940 0.26 Binding ≤ 10μM
KCC2A_HUMAN Q9UQM7 CaM Kinase II Alpha, Human 350 0.28 Binding ≤ 10μM
KCC2B_HUMAN Q13554 CaM Kinase II Beta, Human 2300 0.25 Binding ≤ 10μM
KCC2D_HUMAN Q13557 CaM Kinase II Delta, Human 760 0.27 Binding ≤ 10μM
KCC2G_HUMAN Q13555 CaM Kinase II Gamma, Human 1100 0.26 Binding ≤ 10μM
KCC4_HUMAN Q16566 CaM Kinase IV, Human 2700 0.24 Binding ≤ 10μM
KKCC1_HUMAN Q8N5S9 CaM-kinase Kinase Alpha, Human 850 0.27 Binding ≤ 10μM
KKCC2_HUMAN Q96RR4 CaM-kinase Kinase Beta, Human 2500 0.25 Binding ≤ 10μM
KC1D_HUMAN P48730 Casein Kinase I Delta, Human 260 0.29 Binding ≤ 10μM
KC1E_HUMAN P49674 Casein Kinase I Epsilon, Human 340 0.28 Binding ≤ 10μM
KC1G1_HUMAN Q9HCP0 Casein Kinase I Gamma 1, Human 1000 0.26 Binding ≤ 10μM
KC1G2_HUMAN P78368 Casein Kinase I Gamma 2, Human 790 0.27 Binding ≤ 10μM
KC1AL_HUMAN Q8N752 Casein Kinase I Isoform Alpha-like, Human 1500 0.25 Binding ≤ 10μM
KC1G3_HUMAN Q9Y6M4 Casein Kinase I Isoform Gamma-3, Human 570 0.27 Binding ≤ 10μM
CSK21_HUMAN P68400 Casein Kinase II Alpha, Human 97 0.31 Binding ≤ 10μM
CSK22_HUMAN P19784 Casein Kinase II Alpha (prime), Human 140 0.30 Binding ≤ 10μM
CTRO_HUMAN O14578 Citron Rho-interacting Kinase, Human 94 0.31 Binding ≤ 10μM
CDK7_HUMAN P50613 Cyclin-dependent Kinase 7, Human 930 0.26 Binding ≤ 10μM
DAPK1_HUMAN P53355 Death-associated Protein Kinase 1, Human 270 0.29 Binding ≤ 10μM
DAPK2_HUMAN Q9UIK4 Death-associated Protein Kinase 2, Human 400 0.28 Binding ≤ 10μM
DAPK3_HUMAN O43293 Death-associated Protein Kinase 3, Human 170 0.30 Binding ≤ 10μM
MP2K1_HUMAN Q02750 Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human 77 0.31 Binding ≤ 10μM
MP2K2_HUMAN P36507 Dual Specificity Mitogen-activated Protein Kinase Kinase 2, Human 120 0.30 Binding ≤ 10μM
MP2K4_HUMAN P45985 Dual Specificity Mitogen-activated Protein Kinase Kinase 4, Human 1400 0.26 Binding ≤ 10μM
MP2K6_HUMAN P52564 Dual Specificity Mitogen-activated Protein Kinase Kinase 6, Human 5500 0.23 Binding ≤ 10μM
CLK2_HUMAN P49760 Dual Specificity Protein Kinase CLK2, Human 150 0.30 Binding ≤ 10μM
CLK4_HUMAN Q9HAZ1 Dual Specificity Protein Kinase CLK4, Human 250 0.29 Binding ≤ 10μM
TTK_HUMAN P33981 Dual Specificity Protein Kinase TTK, Human 180 0.30 Binding ≤ 10μM
DYR1B_HUMAN Q9Y463 Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B, Human 2600 0.24 Binding ≤ 10μM
CLK1_HUMAN P49759 Dual Specificty Protein Kinase CLK1, Human 360 0.28 Binding ≤ 10μM
EPHA6_HUMAN Q9UF33 Ephrin Type-A Receptor 6, Human 2000 0.25 Binding ≤ 10μM
EGFR_HUMAN P00533 Epidermal Growth Factor Receptor ErbB1, Human 9000 0.22 Binding ≤ 10μM
E2AK4_HUMAN Q9P2K8 Eukaryotic Translation Initiation Factor 2-alpha Kinase 4, Human 470 0.28 Binding ≤ 10μM
FGFR1_HUMAN P11362 Fibroblast Growth Factor Receptor 1, Human 1900 0.25 Binding ≤ 10μM
FGFR2_HUMAN P21802 Fibroblast Growth Factor Receptor 2, Human 790 0.27 Binding ≤ 10μM
FGFR3_HUMAN P22607 Fibroblast Growth Factor Receptor 3, Human 380 0.28 Binding ≤ 10μM
FAK1_HUMAN Q05397 Focal Adhesion Kinase 1, Human 1200 0.26 Binding ≤ 10μM
IKKE_HUMAN Q14164 Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit, Human 480 0.28 Binding ≤ 10μM
INSR_HUMAN P06213 Insulin Receptor, Human 1200 0.26 Binding ≤ 10μM
INSRR_HUMAN P14616 Insulin Receptor-related Protein, Human 2000 0.25 Binding ≤ 10μM
E2AK2_HUMAN P19525 Interferon-induced, Double-stranded RNA-activated Protein Kinase, Human 1300 0.26 Binding ≤ 10μM
IRAK3_HUMAN Q9Y616 Interleukin-1 Receptor-associated Kinase 3, Human 1900 0.25 Binding ≤ 10μM
LTK_HUMAN P29376 Leukocyte Tyrosine Kinase Receptor, Human 4200 0.24 Binding ≤ 10μM
CSF1R_HUMAN P07333 Macrophage Colony Stimulating Factor Receptor, Human 3.6 0.37 Binding ≤ 10μM
MKNK2_HUMAN Q9HBH9 MAP Kinase Signal-integrating Kinase 2, Human 5500 0.23 Binding ≤ 10μM
MARK2_HUMAN Q7KZI7 MAP/microtubule Affinity-regulating Kinase 2, Human 440 0.28 Binding ≤ 10μM
MARK4_HUMAN Q96L34 MAP/microtubule Affinity-regulating Kinase 4, Human 2000 0.25 Binding ≤ 10μM
MELK_HUMAN Q14680 Maternal Embryonic Leucine Zipper Kinase, Human 340 0.28 Binding ≤ 10μM
M3K11_HUMAN Q16584 Mitogen-activated Protein Kinase Kinase Kinase 11, Human 1700 0.25 Binding ≤ 10μM
M3K9_HUMAN P80192 Mitogen-activated Protein Kinase Kinase Kinase 9, Human 2600 0.24 Binding ≤ 10μM
M4K1_HUMAN Q92918 Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, Human 15 0.34 Binding ≤ 10μM
M4K3_HUMAN Q8IVH8 Mitogen-activated Protein Kinase Kinase Kinase Kinase 3, Human 210 0.29 Binding ≤ 10μM
M4K4_HUMAN O95819 Mitogen-activated Protein Kinase Kinase Kinase Kinase 4, Human 260 0.29 Binding ≤ 10μM
M4K5_HUMAN Q9Y4K4 Mitogen-activated Protein Kinase Kinase Kinase Kinase 5, Human 300 0.29 Binding ≤ 10μM
MUSK_HUMAN O15146 Muscle, Skeletal Receptor Tyrosine Protein Kinase, Human 100 0.31 Binding ≤ 10μM
MYLK2_HUMAN Q9H1R3 Myosin Light Chain Kinase 2, Human 190 0.29 Binding ≤ 10μM
MYLK4_HUMAN Q86YV6 Myosin Light Chain Kinase Family Member 4, Human 32 0.33 Binding ≤ 10μM
MYLK_HUMAN Q15746 Myosin Light Chain Kinase, Smooth Muscle, Human 360 0.28 Binding ≤ 10μM
MYLK_CHICK P11799 Myosin Light Chain Kinase, Smooth Muscle, Chick 42 0.32 Binding ≤ 10μM
NTRK1_HUMAN P04629 Nerve Growth Factor Receptor Trk-A, Human 480 0.28 Binding ≤ 10μM
NTRK2_HUMAN Q16620 Neurotrophic Tyrosine Kinase Receptor Type 2, Human 990 0.26 Binding ≤ 10μM
TNK1_HUMAN Q13470 Non-receptor Tyrosine-protein Kinase TNK1, Human 1500 0.25 Binding ≤ 10μM
NTRK3_HUMAN Q16288 NT-3 Growth Factor Receptor, Human 220 0.29 Binding ≤ 10μM
NUAK1_HUMAN O60285 NUAK Family SNF1-like Kinase 1, Human 460 0.28 Binding ≤ 10μM
NUAK2_HUMAN Q9H093 NUAK Family SNF1-like Kinase 2, Human 400 0.28 Binding ≤ 10μM
PI51A_HUMAN Q99755 Phosphatidylinositol-4-phosphate 5-kinase Type-1 Alpha, Human 130 0.30 Binding ≤ 10μM
PI42B_HUMAN P78356 Phosphatidylinositol-5-phosphate 4-kinase Type-2 Beta, Human 260 0.29 Binding ≤ 10μM
PHKG1_HUMAN Q16816 Phosphorylase Kinase Gamma Subunit 1, Human 83 0.31 Binding ≤ 10μM
PHKG2_HUMAN P15735 Phosphorylase Kinase Gamma Subunit 2, Human 100 0.31 Binding ≤ 10μM
PGFRA_HUMAN P16234 Platelet-derived Growth Factor Receptor Alpha, Human 1.1 0.39 Binding ≤ 10μM
PGFRB_HUMAN P09619 Platelet-derived Growth Factor Receptor Beta, Human 0.29 0.42 Binding ≤ 10μM
KPCD1_HUMAN Q15139 Protein Kinase C Mu, Human 2400 0.25 Binding ≤ 10μM
KPCD3_HUMAN O94806 Protein Kinase C Nu, Human 2700 0.24 Binding ≤ 10μM
KPCT_HUMAN Q04759 Protein Kinase C Theta, Human 7200 0.22 Binding ≤ 10μM
PKN1_HUMAN Q16512 Protein Kinase N1, Human 1900 0.25 Binding ≤ 10μM
PKN2_HUMAN Q16513 Protein Kinase N2, Human 3800 0.24 Binding ≤ 10μM
FAK2_HUMAN Q14289 Protein Tyrosine Kinase 2 Beta, Human 600 0.27 Binding ≤ 10μM
MERTK_HUMAN Q12866 Proto-oncogene Tyrosine-protein Kinase MER, Human 66 0.31 Binding ≤ 10μM
RIPK1_HUMAN Q13546 Receptor-interacting Serine/threonine-protein Kinase 1, Human 1200 0.26 Binding ≤ 10μM
KS6A1_HUMAN Q15418 Ribosomal Protein S6 Kinase Alpha 1, Human 180 0.30 Binding ≤ 10μM
KS6A2_HUMAN Q15349 Ribosomal Protein S6 Kinase Alpha 2, Human 260 0.29 Binding ≤ 10μM
KS6A3_HUMAN P51812 Ribosomal Protein S6 Kinase Alpha 3, Human 2100 0.25 Binding ≤ 10μM
KS6A4_HUMAN O75676 Ribosomal Protein S6 Kinase Alpha 4, Human 200 0.29 Binding ≤ 10μM
KS6A5_HUMAN O75582 Ribosomal Protein S6 Kinase Alpha 5, Human 150 0.30 Binding ≤ 10μM
KS6A6_HUMAN Q9UK32 Ribosomal Protein S6 Kinase Alpha 6, Human 3100 0.24 Binding ≤ 10μM
STK10_HUMAN O94804 Serine/threonine-protein Kinase 10, Human 230 0.29 Binding ≤ 10μM
STK11_HUMAN Q15831 Serine/threonine-protein Kinase 11, Human 360 0.28 Binding ≤ 10μM
STK16_HUMAN O75716 Serine/threonine-protein Kinase 16, Human 730 0.27 Binding ≤ 10μM
ST17A_HUMAN Q9UEE5 Serine/threonine-protein Kinase 17A, Human 24 0.33 Binding ≤ 10μM
ST17B_HUMAN O94768 Serine/threonine-protein Kinase 17B, Human 320 0.28 Binding ≤ 10μM
SLK_HUMAN Q9H2G2 Serine/threonine-protein Kinase 2, Human 460 0.28 Binding ≤ 10μM
STK24_HUMAN Q9Y6E0 Serine/threonine-protein Kinase 24, Human 100 0.31 Binding ≤ 10μM
STK25_HUMAN O00506 Serine/threonine-protein Kinase 25, Human 360 0.28 Binding ≤ 10μM
STK33_HUMAN Q9BYT3 Serine/threonine-protein Kinase 33, Human 130 0.30 Binding ≤ 10μM
ST38L_HUMAN Q9Y2H1 Serine/threonine-protein Kinase 38-like, Human 2000 0.25 Binding ≤ 10μM
AURKB_HUMAN Q96GD4 Serine/threonine-protein Kinase Aurora-B, Human 340 0.28 Binding ≤ 10μM
AURKC_HUMAN Q9UQB9 Serine/threonine-protein Kinase Aurora-C, Human 810 0.27 Binding ≤ 10μM
MARK3_HUMAN P27448 Serine/threonine-protein Kinase C-TAK1, Human 1100 0.26 Binding ≤ 10μM
CHK1_HUMAN O14757 Serine/threonine-protein Kinase Chk1, Human 1200 0.26 Binding ≤ 10μM
KPCD2_HUMAN Q9BZL6 Serine/threonine-protein Kinase D2, Human 3700 0.24 Binding ≤ 10μM
DCLK1_HUMAN O15075 Serine/threonine-protein Kinase DCLK1, Human 550 0.27 Binding ≤ 10μM
DCLK3_HUMAN Q9C098 Serine/threonine-protein Kinase DCLK3, Human 240 0.29 Binding ≤ 10μM
GAK_HUMAN O14976 Serine/threonine-protein Kinase GAK, Human 44 0.32 Binding ≤ 10μM
LATS1_HUMAN O95835 Serine/threonine-protein Kinase LATS1, Human 850 0.27 Binding ≤ 10μM
LATS2_HUMAN Q9NRM7 Serine/threonine-protein Kinase LATS2, Human 430 0.28 Binding ≤ 10μM
MARK1_HUMAN Q9P0L2 Serine/threonine-protein Kinase MARK1, Human 1500 0.25 Binding ≤ 10μM
STK4_HUMAN Q13043 Serine/threonine-protein Kinase MST1, Human 130 0.30 Binding ≤ 10μM
STK3_HUMAN Q13188 Serine/threonine-protein Kinase MST2, Human 65 0.31 Binding ≤ 10μM
MST4_HUMAN Q9P289 Serine/threonine-protein Kinase MST4, Human 330 0.28 Binding ≤ 10μM
NEK2_HUMAN P51955 Serine/threonine-protein Kinase NEK2, Human 1100 0.26 Binding ≤ 10μM
NEK7_HUMAN Q8TDX7 Serine/threonine-protein Kinase NEK7, Human 3200 0.24 Binding ≤ 10μM
PAK3_HUMAN O75914 Serine/threonine-protein Kinase PAK 3, Human 190 0.29 Binding ≤ 10μM
CDK16_HUMAN Q00536 Serine/threonine-protein Kinase PCTAIRE-1, Human 940 0.26 Binding ≤ 10μM
PIM3_HUMAN Q86V86 Serine/threonine-protein Kinase PIM3, Human 2400 0.25 Binding ≤ 10μM
PLK4_HUMAN O00444 Serine/threonine-protein Kinase PLK4, Human 180 0.30 Binding ≤ 10μM
RIOK1_HUMAN Q9BRS2 Serine/threonine-protein Kinase RIO1, Human 590 0.27 Binding ≤ 10μM
RIOK3_HUMAN O14730 Serine/threonine-protein Kinase RIO3, Human 9700 0.22 Binding ≤ 10μM
SIK1_HUMAN P57059 Serine/threonine-protein Kinase SIK1, Human 2700 0.24 Binding ≤ 10μM
SIK2_HUMAN Q9H0K1 Serine/threonine-protein Kinase SIK2, Human 750 0.27 Binding ≤ 10μM
SRPK1_HUMAN Q96SB4 Serine/threonine-protein Kinase SRPK1, Human 4000 0.24 Binding ≤ 10μM
SRPK2_HUMAN P78362 Serine/threonine-protein Kinase SRPK2, Human 200 0.29 Binding ≤ 10μM
TLK1_HUMAN Q9UKI8 Serine/threonine-protein Kinase Tousled-like 1, Human 630 0.27 Binding ≤ 10μM
TLK2_HUMAN Q86UE8 Serine/threonine-protein Kinase Tousled-like 2, Human 270 0.29 Binding ≤ 10μM
WEE1_HUMAN P30291 Serine/threonine-protein Kinase WEE1, Human 3000 0.24 Binding ≤ 10μM
KIT_HUMAN P10721 Stem Cell Growth Factor Receptor, Human 0.25 0.42 Binding ≤ 10μM
TNIK_HUMAN Q9UKE5 TRAF2- And NCK-interacting Kinase, Human 90 0.31 Binding ≤ 10μM
ACK1_HUMAN Q07912 Tyrosine Kinase Non-receptor Protein 2, Human 4900 0.23 Binding ≤ 10μM
ABL1_HUMAN P00519 Tyrosine-protein Kinase ABL, Human 1200 0.26 Binding ≤ 10μM
BLK_HUMAN P51451 Tyrosine-protein Kinase BLK, Human 750 0.27 Binding ≤ 10μM
FER_HUMAN P16591 Tyrosine-protein Kinase FER, Human 34 0.33 Binding ≤ 10μM
FGR_HUMAN P09769 Tyrosine-protein Kinase FGR, Human 390 0.28 Binding ≤ 10μM
FYN_HUMAN P06241 Tyrosine-protein Kinase FYN, Human 2600 0.24 Binding ≤ 10μM
HCK_HUMAN P08631 Tyrosine-protein Kinase HCK, Human 2200 0.25 Binding ≤ 10μM
ITK_HUMAN Q08881 Tyrosine-protein Kinase ITK/TSK, Human 190 0.29 Binding ≤ 10μM
JAK1_HUMAN P23458 Tyrosine-protein Kinase JAK1, Human 97 0.31 Binding ≤ 10μM
JAK2_HUMAN O60674 Tyrosine-protein Kinase JAK2, Human 1600 0.25 Binding ≤ 10μM
JAK3_HUMAN P52333 Tyrosine-protein Kinase JAK3, Human 580 0.27 Binding ≤ 10μM
LCK_HUMAN P06239 Tyrosine-protein Kinase LCK, Human 2300 0.25 Binding ≤ 10μM
LYN_HUMAN P07948 Tyrosine-protein Kinase Lyn, Human 810 0.27 Binding ≤ 10μM
FLT3_HUMAN P36888 Tyrosine-protein Kinase Receptor FLT3, Human 0.54 0.41 Binding ≤ 10μM
RET_HUMAN P07949 Tyrosine-protein Kinase Receptor RET, Human 24 0.33 Binding ≤ 10μM
TYRO3_HUMAN Q06418 Tyrosine-protein Kinase Receptor TYRO3, Human 2400 0.25 Binding ≤ 10μM
UFO_HUMAN P30530 Tyrosine-protein Kinase Receptor UFO, Human 84 0.31 Binding ≤ 10μM
SRC_HUMAN P12931 Tyrosine-protein Kinase SRC, Human 4900 0.23 Binding ≤ 10μM
SRMS_HUMAN Q9H3Y6 Tyrosine-protein Kinase Srms, Human 62 0.32 Binding ≤ 10μM
TYK2_HUMAN P29597 Tyrosine-protein Kinase TYK2, Human 5100 0.23 Binding ≤ 10μM
YES_HUMAN P07947 Tyrosine-protein Kinase YES, Human 260 0.29 Binding ≤ 10μM
VGFR1_HUMAN P17948 Vascular Endothelial Growth Factor Receptor 1, Human 4.7 0.36 Binding ≤ 10μM
VGFR2_HUMAN P35968 Vascular Endothelial Growth Factor Receptor 2, Human 2.3 0.38 Binding ≤ 10μM
VGFR3_HUMAN P35916 Vascular Endothelial Growth Factor Receptor 3, Human 50 0.32 Binding ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description Species
Activated point mutants of FGFR2
activated TAK1 mediates p38 MAPK activation
Activation of ATR in response to replication stress
Activation of CaMK IV
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
Activation of NIMA Kinases NEK9, NEK6, NEK7
Activation of PKB
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Activation of Rac
AMPK inhibits chREBP transcriptional activation activity
Antigen activates B Cell Receptor (BCR) leading to generation of second messenge
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins
Apoptotic cleavage of cellular proteins
Apoptotic execution phase
ARMS-mediated activation
Ca2+ pathway
CaMK IV-mediated phosphorylation of CREB
Caspase-8 activation by cleavage
CD28 co-stimulation
CD28 dependent PI3K/Akt signaling
CD28 dependent Vav1 pathway
CDO in myogenesis
Cell surface interactions at the vascular wall
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Circadian Clock
Condensation of Prometaphase Chromosomes
Constitutive PI3K/AKT Signaling in Cancer
CREB phosphorylation
CREB phosphorylation through the activation of CaMKII
CREB phosphorylation through the activation of CaMKK
CREB phosphorylation through the activation of Ras
CRMPs in Sema3A signaling
CTLA4 inhibitory signaling
Cyclin A/B1 associated events during G2/M transition
Cyclin A:Cdk2-associated events at S phase entry
Cyclin D associated events in G1
Cyclin E associated events during G1/S transition
DAP12 signaling
DCC mediated attractive signaling
Dimerization of procaspase-8
disassembly of the destruction complex and recruitment of AXIN to the membrane
Downstream signal transduction
Downstream TCR signaling
Dual incision reaction in GG-NER
Dual incision reaction in TC-NER
ECM proteoglycans
Effects of PIP2 hydrolysis
EGFR downregulation
EGFR interacts with phospholipase C-gamma
EGFR Transactivation by Gastrin
EPH-ephrin mediated repulsion of cells
EPH-Ephrin signaling
EPHA-mediated growth cone collapse
EPHB-mediated forward signaling
Ephrin signaling
ERK/MAPK targets
ERK1 activation
ERK2 activation
Factors involved in megakaryocyte development and platelet production
Fc epsilon receptor (FCERI) signaling
FCERI mediated Ca+2 mobilization
FCERI mediated MAPK activation
FCERI mediated NF-kB activation
FCGR activation
Formation of HIV elongation complex in the absence of HIV Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of incision complex in GG-NER
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of the HIV-1 Early Elongation Complex
Formation of transcription-coupled NER (TC-NER) repair complex
Frs2-mediated activation
G alpha (z) signalling events
G beta:gamma signalling through PI3Kgamma
G2/M DNA damage checkpoint
G2/M DNA replication checkpoint
GAB1 signalosome
Gastrin-CREB signalling pathway via PKC and MAPK
Generation of second messenger molecules
Glycogen breakdown (glycogenolysis)
Golgi Associated Vesicle Biogenesis
GPVI-mediated activation cascade
GRB2 events in EGFR signaling
GRB2 events in ERBB2 signaling
GRB2:SOS provides linkage to MAPK signaling for Integrins
Growth hormone receptor signaling
HIV Transcription Initiation
HSF1-dependent transactivation
IKK complex recruitment mediated by RIP1
Import of palmitoyl-CoA into the mitochondrial matrix
Inactivation, recovery and regulation of the phototransduction cascade
Inhibition of PKR
Insulin receptor recycling
Integrin alphaIIb beta3 signaling
Integrin cell surface interactions
Interferon alpha/beta signaling
Interferon gamma signaling
Interleukin receptor SHC signaling
Interleukin-1 signaling
Interleukin-2 signaling
Interleukin-3, 5 and GM-CSF signaling
Interleukin-6 signaling
Interleukin-7 signaling
IRS activation
ISG15 antiviral mechanism
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human
Loss of Nlp from mitotic centrosomes
Loss of proteins required for interphase microtubule organization from the ce
MEK activation
Mitotic Prometaphase
mRNA Capping
MyD88:Mal cascade initiated on plasma membrane
NCAM signaling for neurite out-growth
Nef and signal transduction
Nef Mediated CD4 Down-regulation
Negative regulators of RIG-I/MDA5 signaling
Nephrin interactions
Netrin mediated repulsion signals
Netrin-1 signaling
Neurophilin interactions with VEGF and VEGFR
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
NGF-independant TRKA activation
NOD1/2 Signaling Pathway
NoRC negatively regulates rRNA expression
Nuclear Pore Complex (NPC) Disassembly
Oxidative Stress Induced Senescence
p130Cas linkage to MAPK signaling for integrins
PD-1 signaling
PECAM1 interactions
Phosphorylation of CD3 and TCR zeta chains
PI3K events in ERBB2 signaling
PI3K/AKT activation
PIP3 activates AKT signaling
Platelet Adhesion to exposed collagen
Platelet sensitization by LDL
PLC-gamma1 signalling
PLCG1 events in ERBB2 signaling
Polo-like kinase mediated events
Prolactin receptor signaling
RAF phosphorylates MEK
Ras activation uopn Ca2+ infux through NMDA receptor
Recruitment of mitotic centrosome proteins and complexes
Recycling pathway of L1
Regulation by c-FLIP
Regulation of actin dynamics for phagocytic cup formation
Regulation of AMPK activity via LKB1
Regulation of IFNA signaling
Regulation of IFNG signaling
Regulation of KIT signaling
Regulation of PLK1 Activity at G2/M Transition
Regulation of Rheb GTPase activity by AMPK
Regulation of signaling by CBL
Resolution of Sister Chromatid Cohesion
Retrograde neurotrophin signalling
RIP-mediated NFkB activation via ZBP1
RMTs methylate histone arginines
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase I Chain Elongation
RNA Polymerase I Promoter Escape
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription Termination
RNA Polymerase II HIV Promoter Escape
RNA Polymerase II Pre-transcription Events
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
Role of Abl in Robo-Slit signaling
Role of DCC in regulating apoptosis
Role of LAT2/NTAL/LAB on calcium mobilization
RSK activation
Sema3A PAK dependent Axon repulsion
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
Senescence-Associated Secretory Phenotype (SASP)
Separation of Sister Chromatids
SHC activation
SHC1 events in EGFR signaling
SHC1 events in ERBB2 signaling
Signal attenuation
Signal regulatory protein (SIRP) family interactions
Signal transduction by L1
Signaling by activated point mutants of FGFR1
Signaling by activated point mutants of FGFR3
Signaling by BMP
Signaling by constitutively active EGFR
Signaling by EGFR
Signaling by ERBB2
Signaling by ERBB4
Signaling by FGFR
Signaling by FGFR mutants
Signaling by FGFR2 amplification mutants
Signaling by FGFR3 mutants
Signaling by Hippo
Signaling by Insulin receptor
Signaling by Leptin
Signaling by PDGF
Signaling by SCF-KIT
Signalling to p38 via RIT and RIN
Signalling to RAS
Signalling to STAT3
Smooth Muscle Contraction
Sphingolipid de novo biosynthesis
Synthesis of PIPs at the plasma membrane
t(4;14) translocations of FGFR3
Tat-mediated elongation of the HIV-1 transcript
TNF signaling
TRAF3-dependent IRF activation pathway
TRAF6 mediated IRF7 activation
Trafficking of AMPA receptors
Transcription of the HIV genome
Transcriptional activation of mitochondrial biogenesis
Translocation of GLUT4 to the plasma membrane
Translocation of ZAP-70 to Immunological synapse
TRIF-mediated programmed cell death
TRKA activation by NGF
TRP channels
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
Unblocking of NMDA receptor, glutamate binding and activation
Uptake and function of anthrax toxins
VEGF binds to VEGFR leading to receptor dimerization
VEGFA-VEGFR2 Pathway
VEGFR2 mediated cell proliferation
VEGFR2 mediated vascular permeability
WNT mediated activation of DVL

Analogs ( Draw Identity 99% 90% 80% 70% )