UCSF

ZINC19156872

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
October 24th, 2008 20 Yes

Popular Name: Cyclizine Cyclizine

Find On: PubMed — Wikipedia — Google

CAS Numbers: 303-25-3 , 5897-18-7 , 5897-19-8 , 82-92-8

Other Names:

( -)-1-Diphenylmethyl-4-methylpiperazine

(+-)-1-diphenylmethyl-4-methylpiperazine

(+-)-1-Diphenylmethyl-4-methylpiperazine hydrochloride; 1-(Diphenylmethyl)-4-methylpiperazine monohydrochloride; C18H22N2.HCl; Cyclizine hydrochloride; Cyclizine hydrochloride [BAN]; EINECS 206-136-9; LS-111947; Marezine hydrochloride; Marzine; N-Benzhydr

(+-)-1-diphenylmethyl-4-methylpiperazine hydrochloride; 1-(Diphenylmethyl)-4-methylpiperazine monohydrochloride; Cyclizine HCl; cyclizine monohydrochloride

(+-)-1-diphenylmethyl-4-methylpiperazine; (N-Benzhydryl)(N'-methyl)diethylenediamine; 1-(Diphenylmethyl)-4-methylpiperazine; 1-Benzhydryl-4-methylpiperazin; Cyclizine; N-Benzhydryl-N'-methylpiperazine; N-methyl-N'-benzhydrylpiperazine

(N-Benzhydryl)(N'-methyl)diethylenediamine

1-(Diphenylmethyl)-4-methylpiperazine

1-(Diphenylmethyl)-4-methylpiperazine monolactate; C18H22N2.C3H6O3; CYCLIZINE LACTATE; Cyclizine lactate [USAN:BAN]; LS-175968; MAREZINE; Piperazine, 1-(diphenylmethyl)-4-methyl-, mono(2-hydroxypropanoate)

1-Benzhydryl-4-methylpiperazin

1-Benzhydryl-4-methylpiperazine

1-Diphenylmethyl-4-methylpiperazine

2-hydroxypropanoicacid-1-(diphenylmethyl)-4-methylpiperazine(1:1)

303-25-3; Cyclizine hydrochloride (USP); D03622

303-25-3; Cyclizine hydrochloride; Prestwick_789

5-23-01-00232 (Beilstein Handbook Reference)

5897-19-8; Cyclizine lactate (BAN); D02090; Marezine (TN)

82-92-8

82-92-8; C06930; Cyclizine

AB00053084

AC1L1N61

AC1Q3ZTI

BAN

BAN)

BENZHYDRYLMETHYLPIPERAZIN

BPBio1_000483

BRD-K79501723-001-02-0

BRD-K79501723-003-03-4

BRN 0230441

BSPBio_000439

BSPBio_002095

BW 47-83

C06930

CAS-303-25-3

CHEBI:127546

CHEBI:3994

CHEMBL648

Ciclizina

Ciclizina [INN-Spanish]

Ciclizina [INN-Spanish];Cyclizine Chloride;Cyclizinum [INN-Latin]

ciclizina; cyclizine; cyclizinum

CID6726

Compound 47-83

Cyclizine (BAN

Cyclizine (DCF

Cyclizine (INN)

Cyclizine 2HCl

Cyclizine Chloride

Cyclizine hydrochloride

Cyclizine [INN:BAN:DCF]

Cyclizinum

Cyclizinum [INN-Latin]

D03621

DAP000337

DB01176

DCF

DivK1c_007013

EINECS 201-445-5

Emoquil

FDA

HMS1920A20

HMS2091I08

HSDB 3309

INN

KBio1_001957

KBio2_001334

KBio2_003902

KBio2_006470

KBio3_001315

KBioGR_000809

KBioSS_001334

L000701

LS-111945

Marazine

Marezine

Marezine Hydrochloride

Marzine

MFCD00023293

MolPort-001-798-137

N-Benzhydryl-N'-methylpiperazine

N-Methyl-N'-benzhydrylpiperazine

N-Methyl-N'-benzyhydrylpiperazine

N/A

Nautazine

NCGC00016421-01

NCGC00094634-01

NCGC00094634-02

Ne-Devomit

Neo-Devomit

NSC 26608

NSC26608

Oprea1_429421

Piperazine, 1-(diphenylmethyl)-4-methyl-

Prestwick0_000510

Prestwick1_000510

Prestwick2_000510

Prestwick3_000510

Reis-Fit

SPBio_001187

SPBio_002360

SpecPlus_000917

SPECTRUM1500211

Spectrum2_001174

Spectrum3_000368

Spectrum4_000205

Spectrum5_001594

Spectrum_000854

UNII-QRW9FCR9P2

USP

USP)

USP); Cyclizine HCl (BAN

USP); Cyclizine Hydrochloride (BAN

USP); Cyclizine Lactate (BAN

USP); Cyclizine Lactate (FDA

Valoid

Wellcome

Wellcome preparation 47-83

Wellcome prepn 47-83

Wellcome prepn. 47-83

WLN: T6N DNTJ AYR&R& D1

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.41 9.86 -34.96 1 2 1 8 267.396 3 ↓
Mid Mid (pH 6-8) 3.41 9.31 -30.59 1 2 1 8 267.396 3 ↓
Mid Mid (pH 6-8) 3.41 7.48 -2.54 0 2 0 6 266.388 3 ↓

Vendor Notes

Note Type Comments Provided By
ALOGPS_SOLUBILITY 7.52e-02 g/l DrugBank-approved
Purity 95% Matrix Scientific
Patent Database Links EP1777223; EP1829534; EP1832287; US2003236298; US2005113383; US2006063753; US2006166960; US2007202050; US2007202055; US2007203104; US2007207222; US2007248677; US2007265234; WO2007095043; WO2007103687; WO2007109523; WO2008137609 ChEBI
Therapy H1 antihistamine SMDC Pharmakon
Target Histamine Receptor Selleck Chemicals
Warnings IRRITANT Matrix Scientific
Patent Database Links US2006040900; WO2005099702 ChEBI

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Analogs ( Draw Identity 99% 90% 80% 70% )