| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 1st, 2008 | 26 | Yes |
Popular Name: 2-[(2-isopropyl-4-pyrrolidin-1-yl-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl)methyl]phenol 2-[(2-isopropyl-4-pyrrolidin-1-y…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.35 | 9.01 | -100.87 | 3 | 5 | 2 | 55 | 354.498 | 4 | ↓ |
| Hi High (pH 8-9.5) | 3.35 | 6.26 | -9.56 | 1 | 5 | 0 | 52 | 352.482 | 4 | ↓ |
| Hi High (pH 8-9.5) | 3.35 | 6.6 | -27.7 | 2 | 5 | 1 | 54 | 353.49 | 4 | ↓ |
| Mid Mid (pH 6-8) | 3.35 | 8.66 | -41.44 | 2 | 5 | 1 | 54 | 353.49 | 4 | ↓ |
No pre-computed analogs available. Try a structural similarity search.
![5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine](http://zinc12.docking.org/img/rings/25634.gif)
![7-benzyl-4-pyrrolidino-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine](http://zinc12.docking.org/img/rings/50921.gif)