UCSF

ZINC19594585

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
November 4th, 2008 8 No

Popular Name: Fosfomycin Fosfomycin

Find On: PubMed — Wikipedia — Google

CAS Numbers: 23155-02-4 , 26016-98-8 , 26016-99-9 , 26472-47-9 , 26472-47-9, 23112-90-5(acid) , 78964-85-9 , [26016-98-8] , [26016-99-9]

Other Names:

(−

(-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid

(-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid; (1R,2S)-epoxypropylphosphonic acid; (2R-cis)-(3-Methyloxiranyl)phosphonic acid; 1R-cis-(1,2-epoxypropyl)phosphonic acid; FCM; L-cis-1,2-epoxypropylphosphonic acid; Phosphomycin; cis-(1R,2S)-epoxypropylphosphon

(-)-Phosphonomycin; 1,2-EPOXYPROPYLPHOSPHONIC ACID; Antibiotic 833A; FCN; FM; Fosfocina; Fosfomycin; Fosfomycin (usan/inn); Fosfomycin disodium salt; Fosfomycin sodium; Fosfonomycin; MK 0955; Monurol; Phosphomycin; Phosphomycin disodium salt; Phosphonic a

(1R,2S)(-)-(1,2-Epoxypropyl)phosphonic acid disodium salt

(1R,2S)-(1,2-Epoxypropyl)phosphonic acid, compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1); (2R-cis)-(3-Methyloxiranyl)phosphonic acid, compound with 2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1); C4H11NO3.C3H7O4P; EINECS 279-018-8; FOSFOMY

(1R,2S)-epoxypropylphosphonate

(1R,2S)-epoxypropylphosphonate(1-)

(1R,2S)-epoxypropylphosphonate; (1R,2S)-epoxypropylphosphonic acid; CPD0-1113; L-cis-1,2-epoxypropylphosphonic acid; cis-(1R,2S)-epoxypropylphosphonic acid; fosfomycin; phosphonemycin; phosphonomycin

(1R,2S)-Epoxypropylphosphonate; 23155-02-4; C06454; Fosfomycin; Phosphonomycin

(1R,2S)-epoxypropylphosphonate; fosfomycin; fosfomycin(1-)

(1R,2S)-epoxypropylphosphonic acid

(2R-cis)-(3-Methyloxiranyl)phosphonic acid disodium salt

(3-methyloxiran-2-yl)phosphonate

(_)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid

)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid

mycin

23155-02-4

23155-02-4; D04253; FCM; Fosfomycin (USAN/INN); Phosphonomycin

26016-98-8; D07995; Fosfocin (TN); Fosfomycin calcium

26016-99-9

26016-99-9; D02188; Fosfomycin sodium (JP16); Fosmicin S (TN)

34089_FLUKA

34089_RIEDEL

6F066DFF-696A-4A94-AF78-A28430EBE5BA

AC1L2JXY

AC1L9KC0

AC1Q1URS

AR-1I6648

BIDD:GT0448

BRN 1680831, Fosfocina

C06454

calcium (3-methyloxiran-2-yl)phosphonate

CHEBI:42503; CHEBI:8159; CHEBI:24100

CHEBI:681859

CHEMBL1757

CID446987

CID73491

CPD0-1113

D02188

D04253

DAP000767

DB00828

Disodium (1R,2S)-(1,2-epoxypropyl)phosphonate

Disodium fosfomycin

Disodium phosphonomycin

disodium [(2R,3S)-3-methyloxiran-2-yl]-dioxido-oxo-

disodium [(2R,3S)-3-methyloxiran-2-yl]phosphonate

disodium[(2r,3s)-3-methyloxiran-2-yl]phosphonate

EINECS 247-409-2

FCM

FOM-Na

fos-

fos-; -mycin

Fosfocina

Fosfocina disodium salt

Fosfocina;Fosfomycin disodium salt;Fosfomycin sodium;Fosfonomycin;Phosphomycin;Phosphomycin disodium salt;Phosphonomycin

fosfomicina; fosfomycin; fosfomycine; fosfomycinum

Fosfomycin (BAN

Fosfomycin (calcium)

Fosfomycin (USAN/INN)

Fosfomycin calcium

Fosfomycin calcium salt

Fosfomycin Calciumfor culture media

Fosfomycin disodium

Fosfomycin disodium salt

Fosfomycin disodium salt, Antibiotic for Culture Media Use Only

Fosfomycin sodium

Fosfomycin sodium (JP15)

Fosfomycin sodium salt

Fosfomycin trometamol

Fosfomycin Tromethamine

Fosfomycincalcium

Fosfonomycin

FOSMICIN

Fosmicin S

Fosmicin S (TN)

fosphomycin

I06-1211

INN

L-cis-1,2-epoxypropylphosphonic acid

LS-106593

MFCD00070095

MFCD01706261

MFCD03259176

MFCD07809417

MFCD22741288

MK 955

MolPort-003-847-502

Monuril

Monurol

nchem.1024-comp6

NSC 136017

P5396_SIGMA

Phosphomycin

Phosphomycin calcium

Phosphomycin calcium salt

phosphomycin disodium salt

Phosphonemycin

Phosphonic acid, (1,2-epoxypropyl)-, disodium salt (1R,2S) (-)-

Phosphonic acid, (3-methyloxiranyl)-, disodium salt, (2R-cis)-

Phosphonic acid, (3-methyloxiranyl)-, disodium salt, (2R-cis)- (9CI)

Phosphonomycin

Phosphonomycin disodium salt

Phosphonomycin sodium

Priomicina

Sodium fosfomycin

USAN)

USAN); Fosfomycin Calcium (JAN); Fosfomycin Sodium (JAN)

USAN); Fosfomycin Calcium (JAN); Fosfomycin Sodium (JAN); Fosfomycin Tromethamine (FDA

USAN); Fosfomycin Tromethamine (FDA

Veramina

Z-1282

ZINC19594585

[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid

Download: MOL2 SDF SMILES Flexibase

Annotations

Vendors

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.76 -2.22 -39.02 1 4 -1 73 137.051 1 ↓

Vendor Notes

Note Type Comments Provided By
ALOGPS_SOLUBILITY 4.69e+01 g/l DrugBank-approved
purity 9.500000000000000e+001 Enamine Building Blocks Enamine Building Blocks
therap antibacterial MicroSource Spectrum
Indications Antibiotic KeyOrganics Bioactives
Therapy antimicrobial SMDC MicroSource
UniProt Database Links DRP35_STAAN; DRP35_STAAU; FMTA_STAA8; FMTA_STAAC; FMTA_STAAU; FOSA_PSEAE; FOSA_SERMA; FOSB1_BACAA; FOSB1_BACAC; FOSB1_BACAN; FOSB2_BACAA; FOSB2_BACAC; FOSB2_BACAN; FOSB_BACA2; FOSB_BACAH; FOSB_BACC0; FOSB_BACC1; FOSB_BACC2; FOSB_BACC3; FOSB_BACC4; FOSB_BA ChEBI

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
MURA-1-B UDP-N-acetylglucosamine 1-carboxyvinyltransferase (cluster #1 Of 2), Bacterial Bacteria 118 1.21 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
MURA_ECOLI P0A749 UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Ecoli 118 1.21 Binding ≤ 1μM
MURA_ECOLI P0A749 UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Ecoli 118 1.21 Binding ≤ 10μM

Analogs ( Draw Identity 99% 90% 80% 70% )