| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 5th, 2008 | 28 | Yes |
Popular Name: Doxapram Doxapram
Find On: PubMed — Wikipedia — Google
CAS Numbers: 113-07-5 , 309-29-5 , 33089-61-1 , 7081-53-0 , [309-29-5] , [7081-53-0]
(+-)-doxapram; 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone; Doxapram
1-Ethyl-4-(2-morpholin-4-yl-ethyl)-3,3-diphenyl-pyrrolidin-2-one
1-ethyl-4-(2-morpholin-4-ylethyl)-3,3-diphenylpyrrolidin-2-one
1-Ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone
1-Ethyl-4-(2-morpholinoethyl)-3,3-diphenylpyrrolidin-2-one
1-Ethyl-4-(2-morpholinoethyl)-3,3-diphenylpyrrolidin-2-onemono hydrochloride
1-Ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-2-pyrrolidinone, hydrochloride, hydrate(1:1:1)
1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one
2-Pyrrolidinone, 1-ethyl-4-(2-(4-morpholinyl)ethyl)-3,3-diphenyl-
2-Pyrrolidinone, 1-ethyl-4-(2-(4-morpholinyl)ethyl)-3,3-diphenyl- (9CI)
2-Pyrrolidinone, 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-
2-Pyrrolidinone, 1-ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-
309-29-5; D07873; Docatone (TN); Doxapram (INN)
7081-53-0; D01872; Dopram (TN); Doxapram hydrochloride (USP); Doxapram hydrochloride hydrate (JP16)
CPD000469229; DOXAPRAM HYDROCHLORIDE
CPD000469229; DOXAPRAM HYDROCHLORIDE; SAM001246792
Doxapram (hydrochloride hydrate)
doxapram hydrochloride (anhydrous)
Doxapram hydrochloride monohydrate
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.68 | 9.08 | -11.84 | 0 | 4 | 0 | 33 | 378.516 | 6 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| ALOGPS_SOLUBILITY | 3.43e-02 g/l | DrugBank-approved |
| mechanism | CNS and respiratory stimulant | IBScreen Bioactives ZereneX Building Blocks |
| PUBCHEM_SUBSTANCE_COMMENT | NCC_SAMPLE_SUPPLIER : Sequoia Research Products Ltd.; NCC_SUPPLIER_STRUCTURE_ID : SRP04574d; 1 hydrogen chloride | NIH Clinical Collection via PubChem |
| Target | Others | Selleck Chemicals |
| Target | Potassium Channel | Selleck Chemicals |
| PUBCHEM_SUBSTANCE_COMMENT | SAMPLE_SUPPLIER: Sequoia Research Products Ltd.; SUPPLIER_STRUCTURE_ID: SRP04574d; SALT: 1 hydrogen chloride | NIH Clinical Collection via PubChem |
| mechanism | Stimulates chemoreceptors in the carotid arteries, which in turn, stimulates the respiratory centre in the brain stem | IBScreen Bioactives |
| biological_use | Used in intensive care settings to stimulate the respiratory rate | ZereneX Building Blocks |
