UCSF

ZINC02008866

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
October 10th, 2004 24 No

Popular Name: Linezolid Linezolid

Find On: PubMed — Wikipedia — Google

CAS Numbers: 1000268-74-5 , 129618-40-2; 165800-03-3 , 165800-03-3 , 912472-30-1 , [165800-03-3]

Other Names:

(S)-N-((3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

(S)-N-((3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide hydrate

(S)-N-((3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide hydrochloride

(S)-N-[[3-(3-fluoro-4-morpholinylphenyl)-2-oxo-5-oxazolidinyl]methyl]acetamide

zolid

111GE017

165800-03-3

165800-03-3; C08146; Linezolid

165800-03-3; D00947; Linezolid (JAN/USAN/INN); Zyvox (TN)

AC-16128

AC1L9B3M

Acetamide, N-(((5S)-3-(3-fluoro-4-(4-morpholinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl)-

Acetamide, N-(((5S)-3-(3-fluoro-4-(4-morpholinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl)-; Acetamide, N-((3-(3-fluoro-4-(4-morpholinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl)-, (S)-; C16H20FN3O4; HSDB 7478; LINEZOLID; LS-173594; Linezolid [USAN:INN]; N-(((S)-3-

Acetamide, N-((3-(3-fluoro-4-(4-morpholinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl)-, (S)-

Acetamide, N-[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-

BIDD:GT0404

C08146

C16H20FN3O4

CHEBI:126280

CHEBI:6477

CHEMBL126

CID441401

CPD000466335

CPD000466335; LINEZOLID

CPD000466335; LINEZOLID; SAM001246624

D00947

DAP000398

DB00601

DB08769

FDA

FT-0080803

HMS2051F08

HMS2089K06

HSDB 7478

INN

Linezlid

Linezolid & VRC3375

Linezolid (BAN

Linezolid (JAN/USAN/INN)

Linezolid (Zyvox)

Linezolid [USAN:INN]

Linezolid, 98%+

Linezolid-D3

LS-173594

MFCD00937825

MLS000759444

MLS001424075

MolPort-003-986-503

N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide

N-((3-(3-fluoro-4-morpholinylphenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide

N-({(5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide

N-({5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide, N-[[(S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl]methyl]acetamide

N-[[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

NA

NDA 21-130 Zyvox (linezolid tablets)

NDA 21-131 Zyvox for injection (linezolid injection)

NDA 21-132 Zyvox oral suspension (linzolid oral suspension)

PNU 100766

PNU-100766

PNU-100766, U-100766, Zyvoxid, Zyvoxam, Linezolid

S1408_Selleck

SAM001246624

SMR000466335

TL8001272

U 100766

U-100766

USAN)

ZINC02008866

ZLD

Zyvox

Zyvox (TN)

Zyvoxa

Zyvoxam

Zyvoxid

Zyvoxid, Zyvoxam

Download: MOL2 SDF SMILES Flexibase

Annotations

Vendors

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.92 4.03 -20.29 1 7 0 71 337.351 4 ↓

Vendor Notes

Note Type Comments Provided By
ALOGPS_SOLUBILITY 1.44e+00 g/l DrugBank-approved
Purity 95% Fluorochem
Therapy antibacterial SMDC Iconix
Target Antifection Selleck Chemicals
UniProt Database Links CFR_STAAU; RLMN_STAAE; YHEH_BACSU; YHEI_BACSU ChEBI
PUBCHEM_SUBSTANCE_COMMENT NCC_SAMPLE_SUPPLIER : Sequoia Research Products Ltd.; NCC_SUPPLIER_STRUCTURE_ID : SRP01440l NIH Clinical Collection via PubChem
Target Others Selleck Chemicals
PUBCHEM_SUBSTANCE_COMMENT SAMPLE_SUPPLIER: Sequoia Research Products Ltd.; SUPPLIER_STRUCTURE_ID: SRP01440l NIH Clinical Collection via PubChem

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
Z50212-1-O Escherichia Coli (cluster #1 Of 7), Other Other 950 0.35 Functional ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
Z50212 Z50212 Escherichia Coli 3300 0.32 Functional ≤ 10μM

Analogs ( Draw Identity 99% 90% 80% 70% )