| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| January 19th, 2009 | 7 | No |
Popular Name: Foscarnet sodium Foscarnet sodium
Find On: PubMed — Wikipedia — Google
CAS Numbers: 34156-56-4 , 4428-95-9 , 63585-09-1
34156-56-4; Foscarnet; Prestwick_1024
4428-95-9; C06456; Foscarmet; Foscarnet; Phosphonoformate
Dihydroxyphosphinecarboxylic acid oxide
foscarnet sodique; foscarnet sodium; foscarneto sodico; foscarnetum natricum
FOSCARNET; carboxyphosphonic acid; foscarnet; phosphonomethanoic acid
Phosphonoformic acid trisodium salt hexahydrate
Sodium dioxidophosphinecarboxylate oxide hydrate
Sodium phosphonoformate hexahydrate
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -1.71 | -2.5 | -120.9 | 1 | 5 | -2 | 100 | 123.988 | 1 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| ALOGPS_SOLUBILITY | 1.68e+01 g/l | DrugBank-approved |
| Therapy | antiviral | SMDC MicroSource |
| UniProt Database Links | AR6P6_HUMAN; LSMD1_HUMAN; N42L2_HUMAN; N42L2_MOUSE; N42L2_RAT; PCAT1_HUMAN; PHNHY_PSEFL; PSMD6_HUMAN | ChEBI |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DPOL-3-V | Human Herpesvirus 6 DNA Polymerase (cluster #3 Of 4), Viral | Viruses | 280 | 1.31 | Binding ≤ 10μM |
| Q72547-6-V | Human Immunodeficiency Virus Type 1 Reverse Transcriptase (cluster #6 Of 6), Viral | Viruses | 2030 | 1.14 | Binding ≤ 10μM |
| Z50613-1-O | Avian Myeloblastosis Virus (cluster #1 Of 1), Other | Other | 9310 | 1.01 | Binding ≤ 10μM |
| Z50530-5-O | Human Herpesvirus 5 (cluster #5 Of 5), Other | Other | 7000 | 1.03 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DPOL_VZVD | P09252 | DNA Polymerase, Vzvd | 280 | 1.31 | Binding ≤ 1μM |
| Z50613 | Z50613 | Avian Myeloblastosis Virus | 9310 | 1.01 | Binding ≤ 10μM |
| DPOL_VZVD | P09252 | DNA Polymerase, Vzvd | 280 | 1.31 | Binding ≤ 10μM |
| DPOL_HCMVA | P08546 | Human Herpesvirus 5 DNA Polymerase, Hcmva | 2500 | 1.12 | Binding ≤ 10μM |
| Q72547_9HIV1 | Q72547 | Human Immunodeficiency Virus Type 1 Reverse Transcriptase, 9hiv1 | 2030 | 1.14 | Binding ≤ 10μM |
| Z50530 | Z50530 | Human Herpesvirus 5 | 7000 | 1.03 | Functional ≤ 10μM |
