UCSF

ZINC02558026

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
October 27th, 2004 11 Yes

Popular Name: L-CCG-I L-CCG-I

Find On: PubMed — Wikipedia — Google

CAS Numbers: 117857-93-9 , 117857-95-1

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -2.69 2.66 -94.93 3 5 -1 108 158.133 3 ↓

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
EAA2-2-E Excitatory Amino Acid Transporter 2 (cluster #2 Of 2), Eukaryotic Eukaryotes 4000 0.69 Binding ≤ 10μM
Z104302-3-O Glutamate NMDA Receptor (cluster #3 Of 7), Other Other 10000 0.64 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
EAA2_HUMAN P43004 Excitatory Amino Acid Transporter 2, Human 4000 0.69 Binding ≤ 10μM
Z104302 Z104302 Glutamate NMDA Receptor 10000 0.64 Binding ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description Species
Astrocytic Glutamate-Glutamine Uptake And Metabolism
Transport of inorganic cations/anions and amino acids/oligopeptides

Analogs ( Draw Identity 99% 90% 80% 70% )