UCSF

ZINC00266964

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
September 30th, 2005 13 Yes

Popular Name: L-Tyrosine L-Tyrosine

Find On: PubMed — Wikipedia — Google

CAS Numbers: 122666-87-9 , 14330-68-8 , 16870-43-2 , 3/6/556 , 53587-11-4 , 556-02-5 , 556-03-6 , 60-18-4 , 62595-14-6 , 69847-45-6 , [147245-92-9] , [16870-43-2] , [53587-11-4] , [55520-40-6] , [556-03-6] , [60-18-4]

Other Names:

"DL-Tyrosine, 99%"

(-)-a-Amino-p-hydroxyhydrocinnamate; (-)-a-Amino-p-hydroxyhydrocinnamic acid; (-)-alpha-Amino-p-hydroxyhydrocinnamate; (-)-alpha-Amino-p-hydroxyhydrocinnamic acid; (S)-(-)-Tyrosine; (S)-2-Amino-3-(p-hydroxyphenyl)propionate; (S)-2-Amino-3-(p-hydroxyphenyl

(-)-a-Amino-p-hydroxyhydrocinnamate;(-)-a-Amino-p-hydroxyhydrocinnamic acid;(-)-alpha-Amino-p-hydroxyhydrocinnamate;(-)-alpha-Amino-p-hydroxyhydrocinnamic acid;(S)-(-)-Tyrosine;(S)-2-Amino-3-(p-hydroxyphenyl)propionate;(S)-2-Amino-3-(p-hydroxyphenyl)propi

(-)-alpha-amino-p-hydroxyhydrocinnamic acid; (2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid; (S)-(-)-Tyrosine; (S)-Tyrosine; (S)-alpha-amino-4-hydroxybenzenepropanoic acid; 4-hydroxy-L-phenylalanine; L-Tyrosin

(-)-alpha-Amino-p-hydroxyhydrocinnamic acid; (S)-2-Amino-3-(p-hydroxyphenyl)propionic acid; (S)-3-(p-Hydroxyphenyl)alanine; (S)-Tyrosine; (S)-alpha-Amino-4-hydroxybenzenepropanoic acid; 2-Amino-3-(4-hydroxyphenyl)propanoic acid, (S)-; 4-Hydroxy-L-phenylal

(-)-alpha-Amino-p-hydroxyhydrocinnamic acid; (S)-Tyrosine; (S)-alpha-Amino-4-hydroxybenzenepropanoic acid; 2-Amino-3-(4-hydroxyphenyl)propanoic acid, (S)-; 4-Hydroxy-L-phenylalanine; AI3-09055; Benzenepropanoic acid, alpha-amino-4-hydroxy-, (S)-; EINECS 2

(2S)-2,6-diaminohexanoic acid

(2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid

(2S)-2-aminopentanedioic acid

(2S)-2-aminopropanoic acid

(S)-2-Amino-3-(4-hydroxyphenyl)propanoic acid

(S)-2-Amino-3-(4-hydroxyphenyl)propanoic acid hydrochloride

(S)-2-Amino-3-(4-hydroxyphenyl)propanoicacidhydrochloride

147245-92-9

2-amino-3-(4-hydroxyphenyl)propanoic acid

2-Amino-3-(p-hydroxyphenyl)propionic acid

2-Amino-3-(p-hydroxyphenyl)propionic acid; 3-(p-Hydroxyphenyl)alanine; 556-03-6; C01536; DL-Tyrosine; Tyrosine

3-(4-Hydroxyphenyl)-DL-alanine

3-(4-Hydroxyphenyl)-L-alanine

3-(p-Hydroxyphenyl)alanine

60-18-4; D00022; L-Tyrosine (JP16); Tyrosine (USP/INN)

60-18-4; L-tyrosine; tyr; tyrosine

AC1MIXQC

acetic acid

Aventis brand of copolymer 1

C089995

CHEBI:46070; CHEBI:46161; CHEBI:21411; CHEBI:13181; CHEBI:6313

CID3081884

COP-1

COP-1; Copaxone; Copolymer 1; Copolymer-1; Glatiramer acetate; Glatiramer acetate [USAN]; L-Glutamic acid peptide with L-alanine, L-lysine and L-tyrosine, acetate (salt); L-Glutamic acid polymer with L-alanine, L-lysine and L-tyrosine, acetate (salt); LS-

Copaxone

Copolymer 1

Copolymer-1

D-Tyrosine

DAP001315

disodium L-tyrosinate

DL-Tyrosine

DL-Tyrosine [556-03-6]

DL-Tyrosine, 98%

DL-TYROSINE; [556-03-6]

FDA

Free-Form L-Tyrosine

Glatiramer acetate

Glatiramer acetate [USAN]

H-DL-Tyr-OH

H-Tyr-OH

INN

L-(-)-Tyrosine

L-Glutamic acid peptide with L-alanine, L-lysine and L-tyrosine, acetate (salt)

L-Glutamic acid polymer with L-alanine, L-lysine and L-tyrosine, acetate (salt)

L-Tyrosine benzyl ester p-toluenesulfonate

L-Tyrosine disodium salt 2-hydrate

L-Tyrosine disodium salt, 98%

L-Tyrosine disodium salt; L-Tyrosine sodium salt (1:2)

L-tyrosine hydrochloride

L-tyrosine radical; L-tyrosine(.); L-tyrosinyl

L-Tyrosine, 99%

L-Tyrosine, 99+%

L-Tyrosine, HCl

L-TYROSINE, [1-14C]-

L-TYROSINE,[1-14C]-

L-tyrosine-2,3,5,6-d4

L-TYROSINEDISODIUMSALT

L-tyrosinyl radical

LS-186971

LS-188017; NIACINAMIDE; PYRIDOXINE HYDROCHLORIDE; TPN SUSPENSION; TYROSINE

LS-4172

LS-71889

MFCD00002606

MFCD00012617

MFCD00037203

MFCD00063074

MFCD00079605

MFCD04113403

MFCD27978717

NA

Rxosine

Sodium (S)-2-amino-3-(4-hydroxyphenyl)propanoate

Teva brand of copolymer 1

TV 5010

TV-5010

TV5010

tyrosine

Tyrosine (FDA

Tyrosine (INN

Tyrosine benzyl ester tosylate

Tyrosine Power

UNII-5M691HL4BO

USAN

USP)

Download: MOL2 SDF SMILES Flexibase

Annotations

Vendors

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -1.71 1.17 -36.43 4 4 0 88 181.191 3 ↓

Vendor Notes

Note Type Comments Provided By
UniProt Database Links 123R_IIV6; 1433B_BOVIN; 1433B_HUMAN; 1433B_MACFA; 1433B_MOUSE; 1433B_PONAB; 1433B_RAT; 1433B_SHEEP; 1A110_ARATH; 1A112_ARATH; 2ABB_RAT; 3BP2_HUMAN; 3BP2_MOUSE; 41_BOVIN; 41_HUMAN; 41_MOUSE; 4F2_HUMAN; 4F2_MOUSE; 4F2_RABIT; 4F2_RAT; 6DCS_SOYBN; 7B2_HUMAN ChEBI
Mp [°C] 290 Acros Organics
MP 325 - 327 Enamine Building Blocks
MP 325 °C Indofine
MP 325...327 Enamine Building Blocks
ALOGPS_SOLUBILITY 7.67e+00 g/l DrugBank-experimental
purity 9.500000000000000e+001 Enamine Building Blocks Enamine Building Blocks
Purity 95% Fluorochem
Purity 97% APIChem
Purity 98% Fluorochem
Melting_Point >300? Alfa-Aesar
Melting_Point >300° Alfa-Aesar
Therapy amino acid, nutrient SMDC Pharmakon
Melting_Point ca 325? dec. Alfa-Aesar
Melting_Point ca 325° dec. Alfa-Aesar
Patent Database Links EP1541585; EP1609462; EP1616963; EP1627884; EP1632233; EP1657249; EP1762232; EP1774858; EP1849466; EP1854486; EP1869977; EP1870419; EP1983044; GB1565032; GB1585736; US2004023890; US2004034080; US2004106117; US2005101540; US2006223760; US2006276628; US2007 ChEBI
H phrase H335: May cause respiratory irritation Acros Organics
H phrase H335: May cause respiratory irritation; H315: Causes skin irritation; H319: Causes serious eye irritation Acros Organics
H phrase H335: May cause respiratory irritation; H319: Causes serious eye irritation; H315: Causes skin irritation Acros Organics
P phrase P261: Avoid breathing dust/fume/gas/mist/vapors/spray Acros Organics
P phrase P261: Avoid breathing dust/fume/gas/mist/vapors/spray; P302+ P352: IF ON SKIN: Wash with plenty of soap and water; P280: Wear protective gloves/protective clothing/eye protection/face protection; P305 + P351 + P338: IF IN EYES: Rinse cautiously with water Acros Organics
Notes Ph.Eur, pyrogen free Apollo Scientific Bioactives
R phrase R36/37/38: Irritating to eyes, respiratory system and skin. Acros Organics
Reactome Database Links REACT_111140; REACT_111222; REACT_13410; REACT_13482; REACT_13642; REACT_14843; REACT_15351; REACT_15366; REACT_15389; REACT_15410; REACT_15445; REACT_15455; REACT_15492; REACT_19313; REACT_19377; REACT_2; REACT_21382; REACT_690; REACT_75867; REACT_75920 ChEBI
S phrase S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Acros Organics
S phrase S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39: Wear suitable gloves and eye/face protection. Acros Organics
PUBCHEM_PATENT_ID US4730048; US4806556 IBM Patent Data
Hazard XI: Irritant Acros Organics

Activity (Go SEA)

Direct Reactome Annotations (via ChEBI)

Description Species
Abnormal metabolism in phenylketonuria
Amino acid transport across the plasma membrane
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Antigen processing: Ubiquitination & Proteasome degradation
Catecholamine biosynthesis
Cross-presentation of soluble exogenous antigens (endosomes)
Cytosolic tRNA aminoacylation
Endosomal/Vacuolar pathway
ER-Phagosome pathway
Glutathione synthesis and recycling
Mitochondrial tRNA aminoacylation
Na+/Cl- dependent neurotransmitter transporters
Phenylalanine and tyrosine catabolism
Proton/oligonucleotide cotransporters
Thyroxine biosynthesis

Analogs ( Draw Identity 99% 90% 80% 70% )