| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 7th, 2009 | 19 | No |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.71 | 5.53 | -51.78 | 4 | 3 | 1 | 49 | 275.397 | 6 | ↓ |
| Hi High (pH 8-9.5) | 2.71 | 6 | -39.08 | 4 | 3 | 0 | 49 | 274.389 | 6 | ↓ |
| Hi High (pH 8-9.5) | 2.71 | 5.22 | -6.63 | 3 | 3 | 0 | 47 | 274.389 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FNTA-1-E | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #1 Of 3), Eukaryotic | Eukaryotes | 2300 | 0.42 | Binding ≤ 10μM |
| FNTB-1-E | Protein Farnesyltransferase Beta Subunit (cluster #1 Of 3), Eukaryotic | Eukaryotes | 2300 | 0.42 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FNTB_BOVIN | P49355 | Protein Farnesyltransferase Beta Subunit, Bovin | 2300 | 0.42 | Binding ≤ 10μM |
| FNTA_BOVIN | P29702 | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Bovin | 2300 | 0.42 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Inactivation, recovery and regulation of the phototransduction cascade |
