Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.98	16.94	-134.96	0	5	-2	97	460.655	10	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	5.98	14.96	-47.69	1	5	-1	94	461.663	10	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	5.98	14.96	-60.27	1	5	-1	94	461.663	10	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
FNTA-3-E	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #3 Of 3), Eukaryotic	Eukaryotes	190	0.29	Binding ≤ 10μM
FNTB-3-E	Protein Farnesyltransferase Beta Subunit (cluster #3 Of 3), Eukaryotic	Eukaryotes	190	0.29	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
FNTB_RAT	Q02293	Protein Farnesyltransferase Beta Subunit, Rat	190	0.29	Binding ≤ 1μM
FNTB_HUMAN	P49356	Protein Farnesyltransferase Beta Subunit, Human	190	0.29	Binding ≤ 1μM
FNTA_RAT	Q04631	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Rat	190	0.29	Binding ≤ 1μM
FNTA_HUMAN	P49354	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human	190	0.29	Binding ≤ 1μM
FNTB_RAT	Q02293	Protein Farnesyltransferase Beta Subunit, Rat	190	0.29	Binding ≤ 10μM
FNTB_HUMAN	P49356	Protein Farnesyltransferase Beta Subunit, Human	190	0.29	Binding ≤ 10μM
FNTA_RAT	Q04631	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Rat	190	0.29	Binding ≤ 10μM
FNTA_HUMAN	P49354	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human	190	0.29	Binding ≤ 10μM

Description	Species
Apoptotic cleavage of cellular proteins	Homo sapiens (FNTA_HUMAN)
Inactivation, recovery and regulation of the phototransduction cascade	Rattus norvegicus (FNTB_RAT) Homo sapiens (FNTA_HUMAN)