| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 26th, 2005 | 38 | Yes |
Popular Name: L-692429 L-692429
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.03 | -1.3 | -83.25 | 4 | 9 | 0 | 129 | 509.614 | 7 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| AGTR1-1-E | Type-1 Angiotensin II Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 3600 | 0.20 | Binding ≤ 10μM |
| GHSR-1-E | Ghrelin Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 63 | 0.27 | Binding ≤ 10μM |
| GHRHR-1-E | Growth Hormone-releasing Hormone Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 60 | 0.27 | Functional ≤ 10μM |
| GHSR-1-E | Ghrelin Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 60 | 0.27 | Functional ≤ 10μM |
| Z50597-1-O | Rattus Norvegicus (cluster #1 Of 12), Other | Other | 60 | 0.27 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GHSR_PIG | Q95254 | Ghrelin Receptor, Pig | 63 | 0.27 | Binding ≤ 1μM |
| GHSR_HUMAN | Q92847 | Ghrelin Receptor, Human | 63 | 0.27 | Binding ≤ 1μM |
| GHSR_RAT | O08725 | Ghrelin Receptor, Rat | 60 | 0.27 | Binding ≤ 1μM |
| AGTR1_HUMAN | P30556 | Angiotensin II Type 1 Receptor, Human | 3600 | 0.20 | Binding ≤ 10μM |
| GHSR_RAT | O08725 | Ghrelin Receptor, Rat | 60 | 0.27 | Binding ≤ 10μM |
| GHSR_PIG | Q95254 | Ghrelin Receptor, Pig | 63 | 0.27 | Binding ≤ 10μM |
| GHSR_HUMAN | Q92847 | Ghrelin Receptor, Human | 2800 | 0.20 | Binding ≤ 10μM |
| GHSR_RAT | O08725 | Ghrelin Receptor, Rat | 60 | 0.27 | Functional ≤ 10μM |
| GHRHR_RAT | Q02644 | Growth Hormone-releasing Hormone Receptor, Rat | 60 | 0.27 | Functional ≤ 10μM |
| Z50597 | Z50597 | Rattus Norvegicus | 125 | 0.25 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| G alpha (s) signalling events | |
| Glucagon-type ligand receptors | |
| Peptide ligand-binding receptors |
