Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.91	1.98	-46.73	0	7	-1	83	408.489	6	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	1.50	2.14	-51.37	1	7	0	85	409.497	6	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
AGTR1-1-E	Type-1 Angiotensin II Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	1	0.41	Binding ≤ 10μM
AGTR2-1-E	Angiotensin II Type 2 (AT-2) Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	1	0.41	Binding ≤ 10μM
AGTRB-1-E	Angiotensin II Type 1b (AT-1b) Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	1	0.41	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
AGTR1_HUMAN	P30556	Angiotensin II Type 1 Receptor, Human	1	0.41	Binding ≤ 1μM
AGTR1_RABIT	P34976	Angiotensin II Type 1a (AT-1a) Receptor, Rabit	1	0.41	Binding ≤ 1μM
AGTRB_RAT	P29089	Angiotensin II Type 1b (AT-1b) Receptor, Rat	1	0.41	Binding ≤ 1μM
AGTR2_HUMAN	P50052	Angiotensin II Type 2 (AT-2) Receptor, Human	1	0.41	Binding ≤ 1μM
AGTR1_HUMAN	P30556	Angiotensin II Type 1 Receptor, Human	1	0.41	Binding ≤ 10μM
AGTR1_RABIT	P34976	Angiotensin II Type 1a (AT-1a) Receptor, Rabit	1	0.41	Binding ≤ 10μM
AGTRB_RAT	P29089	Angiotensin II Type 1b (AT-1b) Receptor, Rat	1	0.41	Binding ≤ 10μM
AGTR2_HUMAN	P50052	Angiotensin II Type 2 (AT-2) Receptor, Human	1	0.41	Binding ≤ 10μM

Description	Species
G alpha (i) signalling events	Homo sapiens (AGTR2_HUMAN)
G alpha (q) signalling events	Homo sapiens (AGTR1_HUMAN) Rattus norvegicus (AGTRB_RAT)
Peptide ligand-binding receptors	Rattus norvegicus (AGTRB_RAT) Homo sapiens (AGTR1_HUMAN)