UCSF

Angiotensin II Type 2 (AT-2) Receptor, Human (493 Compounds)

Swissprot:
AGTR2_HUMAN
Stitch:
AGTR2_HUMAN
UniProt:
P50052
ChEMBL:
CHEMBL4607
Reactome:
REACT_19231
REACT_14819
PDB:
AGTR2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 493 12 7 4
Binding ≤ 1μM 439 11 7 4
Functional ≤ 10μM 70 3 3 2

Reactome Network (2)

Reactome ID Description Species
REACT_19231 G alpha (i) signalling events Homo sapiens
REACT_14819 Peptide ligand-binding receptors Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
AGTR1_HUMAN P30556 CHEMBL227 Angiotensin II Type 1 Receptor, Human 352
EDNRA_HUMAN P25101 CHEMBL252 Endothelin Receptor ET-A, Human 2
EDNRB_HUMAN P24530 CHEMBL1785 Endothelin Receptor ET-B, Human 2
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
AGTR2_RAT P35351 CHEMBL257 Angiotensin II Type 2 (AT-2) Receptor, Rat 988 10 7 4
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
AGTR1_HUMAN P30556 CHEMBL227 Angiotensin II Type 1 Receptor, Human 1,045 14 9 13

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
AGTR1_HUMAN P30556 CHEMBL227 Angiotensin II Type 1 Receptor, Human 352
AGTRB_RAT P29089 CHEMBL263 Angiotensin II Type 1b (AT-1b) Receptor, Rat 213
AGTRA_RAT P25095 CHEMBL329 Angiotensin II Type 1a (AT-1a) Receptor, Rat 175
AGTR2_RAT P35351 CHEMBL257 Angiotensin II Type 2 (AT-2) Receptor, Rat 77
AGTR1_BOVIN P25104 CHEMBL3374 Angiotensin II Type 1a (AT-1a) Receptor, Bovin 61
AGTR1_RABIT P34976 CHEMBL3948 Angiotensin II Type 1a (AT-1a) Receptor, Rabit 60
AGTR1_PIG P30555 CHEMBL5743 Type-1 Angiotensin II Receptor, Pig 4
Z50592 Z50592 CHEMBL374 Oryctolagus Cuniculus 3
AGTR1_CAVPO Q9WV26 CHEMBL1671613 Type-1 Angiotensin II Receptor, Guinea Pig 2
EDNRA_HUMAN P25101 CHEMBL252 Endothelin Receptor ET-A, Human 2
EDNRB_HUMAN P24530 CHEMBL1785 Endothelin Receptor ET-B, Human 2
Q2XUH7_PIG Q2XUH7 CHEMBL1163122 Angiotensin Type II Receptor, Pig 2
Z80902 Z80902 CHEMBL614150 HASMC (Aortic Smooth Muscle Cells) 2
ACE_HUMAN P12821 CHEMBL1808 Angiotensin-converting Enzyme, Human 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1

Most Common Rings