UCSF

ZINC03798247

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
September 26th, 2005 20 No

Popular Name: CLOFARABINE CLOFARABINE

Find On: PubMed — Wikipedia — Google

CAS Numbers: 123318-82-1 , [123318-82-1]

Other Names:

(2R,3R,4S,5R)-5-(6-Amino-2-chloro-purin-9-yl)-4-fluoro-2-hydroxymethyl-tetrahydro-furan-3-ol

(2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol

(2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol, 2-chloro-2?-arabino-fluoro-2?-deoxyadenosine

(2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol; 2-chloro-9-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)adenine; 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine; CAFdA; Cl-F-Ara-A; clofarabine

arabine

123318-82-1

123318-82-1; Clofarabine (JAN/USAN/INN); Clolar (TN); D03546

2-chloro-9-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)adenine

2-Chloro-9-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-9H-purin-6-amine

2-Chloro-9-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-9H-purin-6-amine; 2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-6-amine; 2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine; 9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-beta-

2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-6-amine

2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine

2-Cl-2'-F-araA

3S211048

5-(6-amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol

9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-

AC-274

AC1L3OC8

AKOS005063562

Bio-0121

C1-F-Ara-A

CAFdA

CFB

CHEBI:681569

CHEMBL1750

CID119182

Cl-F-Ara-A

clofarabina

clofarabina; clofarabine; clofarabinum

Clofarabine

Clofarabine (BAN

Clofarabine (USAN/INN)

Clofarabine [USAN]

clofarabinum

Clofarex

Clolar

Clolar (TN)

Clolar, Evoltra

Clolar, Evoltra, Clofarabine

Clolar

D03546

DAP000849

DB00631

DB07554

Evoltra

FDA

FT-0082882

HMS2090A07

INN

LS-126466

MFCD00871077

MolPort-005-941-711

QA-3028

S1218_Selleck

SAR-393590

UNII-762RDY0Y2H

USAN)

ZINC03798247

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.12 -8.62 -11.55 4 8 0 119 303.681 2 ↓

Vendor Notes

Note Type Comments Provided By
biological_use . ZereneX Building Blocks
ALOGPS_SOLUBILITY 4.89e+00 g/l DrugBank-approved
Purity 99% Fluorochem
Therapy antineoplastic SMDC Pharmakon
Target DNA/RNA Synthesis Selleck Chemicals
mechanism Purine nucleoside antimetabolite ZereneX Building Blocks
biological_use Used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), acute myeloid leukaemia (AML) and juvenile myelomonocytic leukaemia (JMML) IBScreen Bioactives

Activity (Go SEA)

Analogs ( Draw Identity 99% 90% 80% 70% )