UCSF

ZINC03830405

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
September 30th, 2005 29 No

Popular Name: Cefazolin Sodium Cefazolin Sodium

Find On: PubMed — Wikipedia — Google

CAS Numbers: 25953-19-9 , 27164-46-1 , 27164-46-1, 25953-19-9 [c , 27164-46-1, 25953-19-9 [cefazolin] , [25953-19-9]

Other Names:

(6R,7R)-3-(5-Methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-8-oxo-7-(2-tetrazol-1-yl-acetylamino)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

(6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; CEZ; Cefamezin; Cephamezine; Cephazolidin; Cephazolin; Cephazoline

25953-19-9; C06880; Cefazolin

25953-19-9; CEZ; Cefazolin (USP); D02299

27164-46-1; CEFAZOLIN SODIUM SALT; CPD001491644; SAM002564200

27164-46-1; Cefazolin sodium salt; Prestwick_975

3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-7-(((1H-tetrazol-1-yl)acetyl)amino)-, (6R-trans)-, sodium salt; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(((5-methyl-1,3,4-thiadi

5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[(1H-tetrazol

629

Ancef

cef-

Cefazil

Cefazil sodium salt, Cefamedin sodium salt

Cefazolin

Cefazolin (BAN

Cefazolin (sodium)

Cefazolin sodium salt

Cefazolin Sodium Sterile

cefazolin(1-)

cefazolin; cefazolina; cefazoline; cefazolinum

Cefazoline

Cefazoline sodium

Cefazoline;Cephazolin;CEZ

Cefazolinfor culture media

cefazolinsodiumsalt

Cephamezine

Cephazolin

CEZ

CHEBI:3482

CPD001491644; Cefazolin Sodium; SAM002564200

INN

JAN

Kefzol

MFCD00056883

MFCD00243010

MFCD00767909

MFCD01543207

SK&F-41558

SK&F-41558; 46083

sodium 3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

sodium 3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-{[2-(1H-1,2,3,4-tetraazol-1-yl)acetyl]amino}-5-thia-1-aza

Store at 2-8°C

USAN

USAN)

USP

USP)

USP); Cefazolin Sodium (FDA

Zolicef

Download: MOL2 SDF SMILES Flexibase

Annotations

Vendors

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -1.55 4.69 -76.75 1 12 -1 159 453.511 7 ↓

Vendor Notes

Note Type Comments Provided By
biological_use Antibiotic ZereneX Building Blocks
Molecular_Solubility 3.061 Bitter DB
MP 190 TCI
ALOGPS_SOLUBILITY 4.87e-01 g/l DrugBank-approved
Purity 97% Fluorochem
Therapy antibacterial SMDC MicroSource
biological_use Antibiotic IBScreen Bioactives
PUBCHEM_PATENT_ID EP0007753A1; EP0009845A1; EP0055041A2; EP0104232A1; EP0134078A2; EP0225230A1; EP0273156A2; EP0281391A1; EP0281391B1; EP0316342B1; EP0327081A2; EP0327081B1; EP0335378A2; EP0335378B1; EP0349256A1; EP0357665B1; EP0414806B1; EP0452837A2; EP0452837B1; EP047103 IBM Patent Data
mechanism Mucopeptide synthesis inhibitor IBScreen Bioactives
PUBCHEM_SUBSTANCE_COMMENT NCC_SAMPLE_SUPPLIER : LightBiologicals; NCC_SUPPLIER_STRUCTURE_ID : C-3538; NCC_SUPPLIER_SAMPLE_COMMENTS : WHITE POWDER; 1 Sodium NIH Clinical Collection via PubChem
PUBCHEM_SUBSTANCE_COMMENT SAMPLE_SUPPLIER: LightBiologicals; SUPPLIER_STRUCTURE_ID: C-3538; SALT: 1 Sodium; SUPPLIER_COMMENTS: WHITE POWDER NIH Clinical Collection via PubChem
UniProt Database Links YAFQ_ECOLI ChEBI

Activity (Go SEA)

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.