UCSF

ZINC00403079

Substance Information

In ZINC since Heavy atoms Benign functionality
September 30th, 2005 18 Yes

Other Names:

( -)-Midodrin hydrochloride

( -)-Midodrine hydrochloride

()-1-(2,5-Dimethoxyphenyl)-2-glycinamidoethanol

(+-)-1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol hydrochloride

(+-)-1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol hydrochloride; (+-)-2-Amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)acetamide monohydrochloride; (+-)-Midodrine hydrochloride; A 4020 Linz; Acetamide, 2-amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)-,

(+-)-2-Amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)acetamide monohydrochloride

(+-)-2-amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)acetamide; 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol; 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamide; DL-N1-(beta-Hydroxy-2,5-dimethoxyphenethyl)glycinamid; Midodrine

(+-)-Midodrine hydrochloride

(+/-)-1-(2,5-Dimethoxyphenyl)-2-glycinamidoethanol

(RS)-N'-(beta-Hydroxy-2,5-dimethoxy-phenethyl)glycinamid

(RS)-N'-(beta-Hydroxy-2,5-dimethoxy-phenethyl)glycinamid; 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol; 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamid; 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethylacetamide; Acetamide, 2-amino-N-(2-(2,5-dimeth

(±)-1-(2,5-Dimethoxyphenyl)-2-glycinamidoethanol

1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol

1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol hydrochloride

2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamid

2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamide

2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethylacetamide

2-Amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)acetamide monohydrochloride

2-Amino-N-(2-(2,5-dimethoxyphenyl)-2-hyyroxyethyl)acetamide monohydrochloride

2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide

2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide hydrochloride

3092-17-9

3092-17-9 (mono-hydrochloride)

3092-17-9; CPD000058833; Pro-Amatine; SAM002564219

3092-17-9; D01307; Midodrine hydrochloride (JAN/USAN); Pro-Amatine (TN)

3092-17-9; Midodrine hydrochloride; Prestwick_625

42794-76-3

42794-76-3 (Parent)

42794-76-3; C07890; Midodrine

42794-76-3; D08220; Midodrine (INN)

43218-56-0

97476-58-9

A 4020 Linz

A-4020 Linz

A-4020 Linz; ST-1085 [As The Base]; ST-1085; St. Peter 224

A-4020 Linz; ST-1085; ST-1085 [As The Base]; St. Peter 224

AB00053715

AC1L1HMJ

AC1L2BU9

Acetamide, 2-amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)-

Acetamide, 2-amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)-, monohydrochloride

Acetamide, 2-amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)-, monohydrochloride, (+-)-

Acetamide, 2-amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)-, hydrochloride

Acetamide, 2-amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)-, monohydrochloride, (+-)-

Acetamide,2-amino-N-[2- -2-hydroxyethyl]-, -

ACETAMIDE,2-AMINO-N-[2-(2,5-DIMETHOXYPHENYL)-2-HYDROXYETHYL]-,(R)-

Alphamine

Amatine

BPBio1_000157

BRD-A79981887-003-05-7

BSPBio_000141

BSPBio_003150

C07890

C12H18N2O4

C12H18N2O4.HCl

CHEBI:31847

CHEBI:6933

CHEMBL1200461

CID18340

CID4195

CPD000058833

CPD000058833; Midodrine hydrochloride; Pro-Amatine; SAM002564219

D01307

D08220

DAP000229

DB00211

DivK1c_000955

DL-N1-(beta-Hydroxy-2,5-dimethoxyphenethyl)glycinamid

EINECS 255-945-3

EINECS 256-148-3

Gutron

Hipertan

HMS1568H03

HMS1922O03

I06-0865

IDI1_000955

INN); Midodrine HCl (FDA

INN); Midodrine Hydrochloride (FDA

JAN

KBio1_000955

KBio2_002121

KBio2_004689

KBio2_007257

KBio3_002650

KBioGR_000763

KBioSS_002121

LS-174957

LS-8042

LS-8052

M8277_FLUKA

M8277_SIGMA

Metligene

MFCD00079455

MFCD00865849

Midamine

Midodrin

Midodrin;Midodrina [INN-Spanish];Midodrine HCL;Midodrine hydrochloride;Midodrinum [INN-Latin]

Midodrina

Midodrina [INN-Spanish]

midodrina; midodrine; midodrinum

Midodrine

Midodrine (BAN

Midodrine (INN)

Midodrine HCl

Midodrine Hydrochloride

Midodrine hydrochloride (JAN/USAN)

Midodrine hydrochloride [USAN:JAN]

Midodrine hydrochloride [USAN]

Midodrine hydrochloride, 98.5%+

Midodrine Monohydrochloride

Midodrine [BAN:INN]

Midodrine [INN:BAN]

midodrine(1+)

Midodrinum

Midodrinum [INN-Latin]

MLS001332567

MLS001332568

MLS002154233

MolPort-003-666-473

MolPort-003-849-221

N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]glycinamide

N-{2-[2,5-bis(methyloxy)phenyl]-2-hydroxyethyl}glycinamide

NCGC00095311-01

NCGC00178238-01

NCGC00178238-02

NINDS_000955

ORVATEN

Prestwick0_000191

Prestwick1_000191

Prestwick2_000191

Prestwick3_000191

Prestwick_625

Pro-Amatine

Pro-Amatine (TN)

ProAmatine

SAM002564219

SBB066174

SMR000058833

SPBio_001390

SPBio_002062

SPECTRUM1503257

Spectrum2_001545

Spectrum3_001585

Spectrum4_000192

Spectrum5_000962

Spectrum_001641

St 1085

ST-1085

St. Peter 224

TL8002369

TS 701

UNII-59JV96YTXV

UNII-6YE7PBM15H

USAN)

[+/-]-1-[2,5-Dimethoxyphenyl]-2-glycinamidoethanol

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -0.42 -2.6 -48.06 5 6 1 95 255.294 6
Hi High (pH 8-9.5) -0.42 -3.01 -11.25 4 6 0 94 254.286 6

Vendor Notes

Note Type Comments Provided By
ALOGPS_SOLUBILITY 4.45e+00 g/l DrugBank-approved
Therapy antihypertensive, vasoconstrictor SMDC Iconix
Indications antihypotensive KeyOrganics Bioactives
PUBCHEM_SUBSTANCE_COMMENT NCC_SAMPLE_SUPPLIER : LightBiologicals; NCC_SUPPLIER_STRUCTURE_ID : M-0051; NCC_SUPPLIER_SAMPLE_COMMENTS : WHITE POWDER; 1 hydrogen chloride NIH Clinical Collection via PubChem
PUBCHEM_SUBSTANCE_COMMENT SAMPLE_SUPPLIER: LightBiologicals; SUPPLIER_STRUCTURE_ID: M-0051; SALT: 1 hydrogen chloride; SUPPLIER_COMMENTS: WHITE POWDER NIH Clinical Collection via PubChem
Patent Database Links US2003026850; US2005070552; US2005261242; US2007207222; US2008255073; WO2005018635; WO2006091697; WO2007103687 ChEBI

Activity (Go SEA)

Analogs ( Draw Identity 99% 90% 80% 70% )