UCSF

ZINC00403588

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
October 5th, 2005 12 Yes

Popular Name: Synephrine Synephrine

Find On: PubMed — Wikipedia — Google

CAS Numbers: 136-38-9 , 16589-24-5 , 582-84-3 , 5985-28-4 , 67-04-9 , 94-07-5 , [16589-24-5] , [582-84-3] , [5985-28-4] , [94-07-5]

Other Names:

"Synephrine, 98%"

(+)-p-Synephrine;(+)-Synephrine;(+)-[(methylamino)methyl]-Benzenemethano;Analeptin;Oxedrine;Parasympatol;Simpalon;Simpatol;Sympaethamin;Sympaethamine;Sympatol;Synephrine

(+,-)-Synephrine

(+-)-1-(4-Hydroxyphenyl)-2-methylaminoethanol tartrate; (+-)-1-(4-Idrossifenil)-2-metilaminoetanolo tartrato [Italian]; Benzyl alcohol, p-hydroxy-alpha-((methylamino)methyl)-, tartrate (2:1) (salt); Bis((1)-(beta-,4-dihydroxyphenethyl)methylammonium) (R-(

(+/-)-Synephrine; 1-(4-Hydroxyphenyl)-2-(methylamino)ethanol; 94-07-5; C04548; Synephrine

(+/-)-Synephrine; 94-07-5; D07148; Oxedrine (BAN)

(-)-4-hydroxy-alpha-[(methylamino)methyl]benzenemethanol; (-)-Oxedrine; (-)-Sympatol; (-)-Synephrine; (-)-p-hydroxy-alpha-[(methylamino)methyl]benzyl alcohol; D(-)-Synephrine

(±)-Synephrine

(beta-,4-dihydroxyphenethyl)methylammonium hydrogen [R-(R*,R*)]-tartrate

1-(4-hydroxyphenyl)-2-(methylamino)ethanol; 1-(4-hydroxyphenyl)-2-methylaminoethanol; 1-4-HYDROXYPHENYL-2-METHYLAMINOETHAN; 4-hydroxy-alpha-[(methylamino)methyl]benzenemethanol; beta-methylamino-alpha-(4-hydroxyphenyl)ethyl alcohol; oxedrine; sympatol

1-(4-Hydroxyphenyl)-2-methylaminoethano

1-(4-hydroxyphenyl)-2-methylaminoethanol; 4-hydroxy-alpha-[(methylamino)methyl]benzenemethanol; Oxedrine; Sympatol; Synephrine; beta-methylamino-alpha-(4-hydroxyphenyl)ethyl alcohol; p-hydroxy-alpha-[(methylamino)methyl]benzyl alcohol

2-Hydroxy-2-(4-hydroxyphenyl)-N-methylethanaminium chloride

4-((R)-1-Hydroxy-2-methylamino-ethyl)-phenol

4-(1-Hydroxy-2-(methylamino)-ethyl)phenol hydrochloride

4-(1-Hydroxy-2-(methylamino)ethyl)phenol

4-(1-Hydroxy-2-(methylamino)ethyl)phenol hydrochloride

4-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol

4-[1-hydroxy-2-(methylamino)ethyl]phenol

4-[1-hydroxy-2-(methylamino)ethyl]phenol 2,3-dihydroxysuccinate (salt)

4-[1-Hydroxy-2-(methylamino)ethyl]phenol Hydrochloride

4-[1-hydroxy-2-(methylamino)ethyl]phenolhydrochloride

5985-28-4; D08309; Ocuton (TN); Oxedrine hydrochloride

Analeptin

benzenemethanol, 4-hydroxy-alpha-[(methylamino)methyl]-

benzenemethanol, 4-hydroxy-alpha-[(methylamino)methyl]-, 2,3-dihydroxybutanedioate (1:1) (salt)

CHEBI:11190; CHEBI:18964; CHEBI:570

CPD000059111; SAM001246896; SYNEPHRINE

CPD000059111; SYNEPHRINE; 94-07-5

D-synephrine

Ethaphene

HYDROXYMETHYLAMINOETHYLPHENOLHYDROCHLORID

MFCD00002370

MFCD00050566

MFCD00051101

MFCD00151120

MFCD23103451

N/A

OR-0383

Oxedrine

Oxedrine (BAN)

Oxedrine, p-Synephrine, Sympatol, Parasympatol, Sympaethamine

Oxedrine

p-Synephrine

Simpalon

Sympathol

Synephrine (hydrochloride)

Synephrine (Oxedrine)

Synephrine HCl

Synephrine hydrochloride

Synephrine Tartrate

Synephrine [94-07-5]

SYNEPHRINE; [94-07-5]

Synephrine;Oxedrine

synephrinetartrate

synephrinium

Download: MOL2 SDF SMILES Flexibase

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Vendors

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.43 -0.72 -42.44 4 3 1 57 168.216 3 ↓
Hi High (pH 8-9.5) 0.43 -2.17 -5.01 3 3 0 52 167.208 3 ↓

Vendor Notes

Note Type Comments Provided By
biological_use . ZereneX Building Blocks
M.P 180-181C Indofine Natural Products
M.P 187 °C Indofine Natural Products
Purity 95% Fluorochem
Purity 95+% Matrix Scientific
UniProt Database Links ADA2A_HUMAN; ADA2B_HUMAN; OAR1_LYMST; OAR2_LYMST; OAR_DROME ChEBI
biological_source Alkaloid from a number of Coryphantha spp. and from Dolichothele longimamma (Cactaceae) ZereneX Building Blocks
mechanism alpha1-Adrenergic agonist IBScreen Bioactives IBScreen Bioactives
Target Androgen Receptor Selleck Chemicals
Therapy anti-obesity SMDC Pharmakon
mechanism beta3-Adrenergic agonist IBScreen Bioactives
Patent Database Links EP1568770; US2006110343; WO2005108381; WO2007111958 ChEBI
Warnings IRRITANT Matrix Scientific
PUBCHEM_SUBSTANCE_COMMENT NCC_SAMPLE_SUPPLIER : Sigma Chemical Company; NCC_SUPPLIER_STRUCTURE_ID : s0752 NIH Clinical Collection via PubChem
biological_use Possesses decongestant props. IBScreen Bioactives
biological_use Promotes weight loss IBScreen Bioactives
PUBCHEM_SUBSTANCE_COMMENT SAMPLE_SUPPLIER: Sigma Chemical Company; SUPPLIER_STRUCTURE_ID: s0752 NIH Clinical Collection via PubChem
biological_use Sympathomimetic agent showing vasoconstrictor, hypertensive and bronchial muscle relaxant props. IBScreen Bioactives
PUBCHEM_PATENT_ID US6162459 IBM Patent Data
Indications weight loss KeyOrganics Bioactives
Indications weight loss, vasoconstrictor KeyOrganics Bioactives
APPEARANCE White powder Indofine Natural Products

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Analogs ( Draw Identity 99% 90% 80% 70% )