UCSF

ZINC04097304

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
November 7th, 2005 27 No

Popular Name: Fludrocortisone Fludrocortisone

Find On: PubMed — Wikipedia — Google

CAS Numbers: 127-31-1 , [127-31-1]

Other Names:

(11beta)-9-Fluoro-11,17,21-trihydroxypregn-4-ene-3,20-dione

(8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one

127-31-1

127-31-1; Astonin-H (TN); D07967; Fludrocortisone (INN)

127-31-1; C07004; Fludrocortisone

127-31-1; Fludrocortisone; Prestwick_648

4-08-00-03427 (Beilstein Handbook Reference)

9 .Alpha. Ff

9 Alpha Ff

9 alpha FF; 9 alpha Fludrohydrocortisone; 9 alpha-Fluoro-17-Hydroxycorticosterone; 9 alpha-Fluorohydrocortisone; 9-AF; 9-AFH; 9-Fluoro-11-beta,17,21-trihydroxypregn-4-ene-3,20-dione; 9-Fluoro-11beta,17,21-trihydroxypregn-4-ene-3,20-dione; 9-Fluoro-17-Hydr

9 alpha Fludrohydrocortisone

9 alpha Fluoro 17 Hydroxycorticosterone

9 alpha Fluorohydrocortisone

9 alpha-Fludrocortisone

9 alpha-Fluoro-17-Hydroxycorticosterone

9 alpha-Fluorocortisol

9 alpha-Fluorohydrocortisone

9 Fluoro 17 Hydroxycortisone

9 Fluorocortisol

9 Fluorohydrocortisone

9-AF

9-AFH

9-alpha-Fludrocortisone

9-alpha-Fluoro-17-hydroxycorticosterone

9-alpha-Fluorocortisol

9-alpha-Fluorohydrocortisone

9-Fluoro-11-beta,17,21-trihydroxypregn-4-ene-3,20-dione

9-Fluoro-11.beta.,17,21-trihydroxypregn-4-ene-3,20-dione

9-Fluoro-11beta,17,21-trihydroxypregn-4-ene-3,20-dione

9-Fluoro-17-Hydroxycortisone

9-Fluorocortisol

9-Fluorohydrocortisone

9.alpha.-Fluoro-11.beta.,17.alpha.,21-trihydroxy-4-pregnene-3,20-dione

9.alpha.-Fluoro-17-hydroxycorticosterone

9.Alpha.-Fluorocortisol

9.Alpha.-Fluorohydrocortisone

9alpha-Fludrocortisone

9alpha-Fluoro-11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione

9alpha-fluoro-11beta,17alpha,21-trihydroxy-pregn-4-ene-3,20-dione

9alpha-fluoro-11beta,17alpha,21-trihydroxy-pregn-4-ene-3,20-dione; Fludrocortisone; Fluohydrisone; Fluorocortisol; Fluorocortisone; LMST02030103; bmse000987

9alpha-fluoro-11beta,17alpha,21-trihydroxy-pregn-4-ene-3,20-dione; Fludrocortisone; Fluohydrisone; Fluorocortisol; Fluorocortisone; LMST02030103; bmse001009

9alpha-Fluoro-17-hydroxycorticosterone

9alpha-Fluoro-hydrocortisone

9alpha-Fluorocortisol

AC1L1LI8

AC1Q5HJH

Alflorone

Astonin

Astonin H

Astonin Merck

Astonin-H

Astonin-H (TN)

BRN 3014278

C07004

C21H29FO5

CHEBI:46556; CHEBI:5101

CHEBI:50885

CHEMBL1201388

CID31378

Corticosterone, 9-fluoro-17-hydroxy-

Cortisol, 9-fluoro-

D005438

D07967

DAP001105

DB00687

DB02478

EINECS 204-833-2

F-COL

F-Cortef

FCOL

Florinef

Fludrocortisona

Fludrocortisona [INN-Spanish]

Fludrocortisone (INN)

Fludrocortisone Acetate

Fludrocortisone [INN:BAN]

Fludrocortisonum

Fludrocortisonum [INN-Latin]

Fludrocortone

Fludrone

Fludronef

Fluodrocortisone

Fluohydrisone

Fluohydrocortisone

Fluorocortisol

Fluorocortisone

HSDB 3332

Hydrocortisone-9alpha-fluoro

LMST02030103

LS-118690

Merck Brand of Fludrocortisone

Merck, Astonin

MFCD00083333

MolPort-005-943-437

NCGC00181081-01

NSC 11318

NSC11318

Pregn-4-ene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-, (11.beta.)-

Pregn-4-ene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-, (11beta)-

Pregn-4-ene-3,20-dione, 9-fluoro-11-beta,17,21-trihydroxy-

Pregn-4-ene-3,20-dione, 9-fluoro-11.beta.,17,21-trihydroxy-

Pregn-4-ene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy-

Pregn-4-ene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy- (8CI)

Prestwick_648

StC 1400

U 5963

UNII-U0476M545B

WLN: L E5 B666 OV MUTJ A1 BF CQ E1 FV1Q FQ

ZINC04097304

ZK5

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.60 3.14 -15.59 3 5 0 95 380.456 2 ↓

Vendor Notes

Note Type Comments Provided By
ALOGPS_SOLUBILITY 2.24e-01 g/l DrugBank-approved
Patent Database Links EP1864668; GB2321455; US2001006962; US2003153544; US2003153545; US2004063677; US2007184114; US2007213296; US2007253899; US2007254853; US2007258969; US2008255073; WO2006091697; WO2007089617; WO2007100902; WO2007103373; WO2007117352 ChEBI

Activity (Go SEA)

Analogs ( Draw Identity 99% 90% 80% 70% )