UCSF

ZINC04097467

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Substance Information

In ZINC since Heavy atoms Benign functionality
November 7th, 2005 28 No

Popular Name: MEGESTROL ACETATE MEGESTROL ACETATE

Find On: PubMed — Wikipedia — Google

CAS Numbers: 595-33-5 , [595-33-5]

Download: MOL2 SDF SMILES Flexibase

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.09 11.68 -15.91 0 4 0 60 384.516 3 ↓

Vendor Notes

Note Type Comments Provided By
mechanism . ZereneX Building Blocks
MP 218 TCI
biological_use against carcinoma of the breast and endometrium IBScreen Bioactives
mechanism Also has direct cytotoxic effects on breast cancer cells in tissue culture and suppresses luteinising hormone release from the pituitary IBScreen Bioactives
Target Androgen Receptor Selleck Chemicals
biological_use Antineoplastic agent IBScreen Bioactives
Purity CP2000 BP98 USP24 APIChem
PUBCHEM_SUBSTANCE_COMMENT NCC_SAMPLE_SUPPLIER : Sequoia Research Products Ltd.; NCC_SUPPLIER_STRUCTURE_ID : SRP01730m NIH Clinical Collection via PubChem
biological_use Oral contraceptive IBScreen Bioactives ZereneX Building Blocks
PUBCHEM_SUBSTANCE_COMMENT SAMPLE_SUPPLIER: Sequoia Research Products Ltd.; SUPPLIER_STRUCTURE_ID: SRP01730m NIH Clinical Collection via PubChem
mechanism The biochemical mechanism of progestin antitumour activity is not well but may involve interaction with progesterone and glucocorticoid receptors, androgenic properties IBScreen Bioactives
mechanism The precise mechanism by which megestrol acetate produces effects in anorexia and cachexia is unknown at the present time IBScreen Bioactives IBScreen Bioactives

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