UCSF

ZINC04212851

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
November 15th, 2005 30 No

Popular Name: Desonide Desonide

Find On: PubMed — Wikipedia — Google

CAS Numbers: 638-94-8 , [638-94-8]

Other Names:

(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one

onide

11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone

11beta,21-dihydroxy-16alpha,17-isopropylidenedioxypregna-1,4-diene-3,20-dione

11beta,21-dihydroxy-16alpha,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione

11beta,21-dihydroxy-16alpha,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione; 11beta,21-dihydroxy-16alpha,17-isopropylidenedioxypregna-1,4-diene-3,20-dione; 11beta,21-dihydroxy-16alpha,17alpha-isopropylidenedioxypregna-1,4-diene-3,20-dione; 16

11beta,21-dihydroxy-16alpha,17alpha-isopropylidenedioxypregna-1,4-diene-3,20-dione

16-alpha-Hydroxyprednisole-16,17-acetonide

16a-Hydroxy-D1-hydrocortisone-16a,17a-acetonide

16alpha,17alpha-isopropylidenedioxyprednisolone

16alpha-hydroxyprednisole-16,17-acetonide

16alpha-hydroxyprednisolone-16alpha,17-acetonide

638-94-8

638-94-8; D03696; Desonide (USAN/INN); Desowen (TN); Verdeso (TN)

AC-2165

AC1L1ZT0

AC1LB9FO

ACETIC ACID, GLACIAL; DESONIDE; LS-187817; TRIDESILON

Apolar

BAN

CHEBI:204734

CHEMBL1201109

CHEMBL987

CID12536

CID5311066

CID578798

D 2083

D-2083

D-2083; D2083

D03696

DAP001188

DB01260

desfluorotriamcinolone acetonide

Desilux

Desocort

Desonate

Desonida

Desonida [INN-Spanish]

desonida; desonide; desonidum

Desonide (BAN

Desonide (FDA

Desonide (USAN/INN)

Desonide [USAN:INN:BAN]

Desonidum

Desonidum [INN-Latin]

Desowen

Desowen (TN)

EINECS 211-351-6

FDA

Flusemidon

Hamiltoderm

I06-0284

INN

Locapred

Locapred, Topifug, Tridesilon

Locapred, Topifug, Tridesilon, Desonide

LS-118407

MFCD00866151

MolPort-003-666-875

MolPort-003-987-087

Prednacinolone

Prednisolone-16,17-acetonide, 16-alpha-hydroxy-

Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-, (11beta,16alpha)-

Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11.beta.,16.alpha.)-

Prenacid

QA-9649

Reticus

S1701_Selleck

Sterax

Steroderm

TL8004516

Topifug

Tridesilon

Tridesonit

UNII-J280872D1O

USAN)

Verdeso

Verdeso (TN)

ZINC04212851

Zotinar

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.57 5.66 -16.38 2 6 0 93 416.514 2 ↓

Vendor Notes

Note Type Comments Provided By
ALOGPS_SOLUBILITY 5.94e-02 g/l DrugBank-approved
Therapy antiinflammatory, glucocorticoid SMDC Pharmakon
PUBCHEM_PATENT_ID EP0051278A1; EP0055870A1; EP0068552A2; EP0068553A1; EP0069385A2; EP0129283A2; EP0129284A2; EP0129285A2; EP0129285B1; EP0164636A2; EP0173478A1; EP0173478B1; EP0227531A2; EP0257063A1; EP0257063B1; EP0257086A1; EP0257086B1; EP0267277B1; EP0277211A1; EP027721 IBM Patent Data
Target Glucocorticoid Receptor Selleck Chemicals
Target Others Selleck Chemicals

Activity (Go SEA)

Analogs ( Draw Identity 99% 90% 80% 70% )