UCSF

ZINC00000431

Substance Information

In ZINC since Heavy atoms Benign functionality
July 23rd, 2004 21 Yes

CAS Numbers: 110032-65-0 , 846-49-1

Other Names:

(+-)-7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one

(+-)-7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one; 2H,1,4-Benzodiazepin-2-one, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-; 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-; 2H-1,4-Benzo

(+/-)-Lorazepam

(+/-)-Lorazepam;O-Chlorooxazepam;O-Chloroxazepam

(S)-LORAZEPAM

azepam

2H,1,4-Benzodiazepin-2-one, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-

2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-

2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-, (+-)-

2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-

5-25-02-00248 (Beilstein Handbook Reference)

7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one

7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one

7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one

7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1H-1,4-benzodiazepin-2(3H)-one

7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1H-benzo[e][1,4]diazepin-2(3H)-one

7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one

846-49-1

846-49-1; Ativan (TN); D00365; Lorazepam (JP16/USP/INN)

AC1L1H3H

AHP Brand of Lorazepam

Almazine

Alzapam

Anxiedin

Anxira

Anzepam

Aplacasse

Aplacassee

Apo Lorazepam

Apo-Lorazepam

ApoLorazepam

Apotex Brand of Lorazepam

Aripax

Ativan

Ativan (TN)

Azurogen

BAN

Baxter Brand of Lorazepam

Bonatranquan

Bonton

BRN 0759084

CHEBI:116959

CHEMBL580

CID3958

CPD000058410

CPD000058410; Lorazepam

CPD000058410; Lorazepam; SAM001246833

CPD000058410; SAM001246833; lorazepam

ct Arzneimittel Brand of Lorazepam

ct-Arzneimittel Brand of Lorazepam

D00365

D008140

DAP000237

DB00186

DEA No. 2885

Delormetazepam

Demethyllormetazepam

Desitin Brand of Lorazepam

DivK1c_000965

Dolorgiet Brand of Lorazepam

Donix

Duralozam

Durazolam

Efasedan

EINECS 212-687-6

Emotion

Emotival

Equitam

FDA

HMS2052H07

HMS503A11

Idalprem

IDI1_000965

INN

JAN

Kalmalin

KBio1_000965

L-Lorazepam Acetate

L1764_SIGMA

Larpose

Laubeel

Llorens Brand of Lorazepam

Lomesta

Lopam

Lorabenz

Lorafen

Loram

Lorans

Lorapam

Lorat

Lorax

Loraz

Lorazene

Lorazep

lorazep von ct

lorazepam (Ativan)

Lorazepam (BAN

Lorazepam (FDA

Lorazepam (JP15/USP/INN)

Lorazepam AHP Brand

Lorazepam Apotex Brand

Lorazepam Baxter Brand

Lorazepam ct-Arzneimittel Brand

Lorazepam Desitin Brand

Lorazepam Dolorgiet Brand

Lorazepam Fabra

Lorazepam Genericon

Lorazepam intensol

Lorazepam Lannacher

Lorazepam Llorens Brand

Lorazepam Medical

Lorazepam Medical Brand

Lorazepam Medix Brand

Lorazepam neuraxpharm

Lorazepam neuraxpharm Brand

Lorazepam Novartis Brand

Lorazepam Novopharm Brand

Lorazepam Nu-Pharm Brand

Lorazepam preservative free

Lorazepam ratiopharm

Lorazepam ratiopharm Brand

Lorazepam Riemser Brand

Lorazepam Wyeth Brand

Lorazepam [USAN:INN:BAN:JAN]

Lorazepam-Efeka

Lorazepam-neuraxpharm

Lorazepam-ratiopharm

Lorazepamum

Lorazepamum [INN-Latin]

Lorazepan Chobet

Lorazepan Richet

Lorazin

Lorazon

Lorenin

Loridem

Lorivan

Lorsedal

Lorsilan

Lorzem

Lozepam

LS-34141

Max Pax

Medical Brand of Lorazepam

Medical, Lorazepam

Medix Brand of Lorazepam

Merck dura Brand of Lorazepam

Merlit

MFCD00063406

MFCD00871816

MolPort-002-051-769

NCGC00159439-02

nchembio747-comp26

Nervistop L

Nervistopl

neuraxpharm Brand of Lorazepam

NINDS_000965

Norlormetazepam

Novartis Brand of Lorazepam

Novhepar

Novo Lorazem

Novo-Lorazem

Novolorazem

Novopharm Brand of Lorazepam

NSC 289758

NSC289758

Nu Loraz

Nu Pharm Brand of Lorazepam

Nu-Loraz

Nu-Pharm Brand of Lorazepam

NuLoraz

O-Chlorooxazepam

O-Chloroxazepam

Orfidal

Orfidal Wyeth

Pro Dorm

Psicopax

Punktyl

Quait

ratiopharm Brand of Lorazepam

Renaquil

Riemser Brand of Lorazepam

Rocosgen

SAM001246833

Securit

Sedatival

Sedazin

Sedicepan

Sedizepan

Serra Pamies Brand of Lorazepam

Sidenar

Silence

Sinestron

Somagerol

Stapam

Tavor

Temesta

Tolid

Tranqipam

Trapax

UNII-O26FZP769L

Upan

USAN

USP)

Vigiten

WLN: T67 GMV JN IHJ CG IQ KR BG

Wy 4036

WY-4036

WY4036

Wyeth Brand of Lorazepam

Wyeth, Orfidal

Wypax

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.47 1.26 -9.16 2 4 0 62 321.163 1

Vendor Notes

Note Type Comments Provided By
ALOGPS_SOLUBILITY 1.76e-02 g/l DrugBank-approved
PUBCHEM_SUBSTANCE_COMMENT NCC_SAMPLE_SUPPLIER : Sequoia Research Products Ltd.; NCC_SUPPLIER_STRUCTURE_ID : SRP01577l; NCC_CONTROLLED_SUBSTANCE : DEA SCHEDULE 4 NIH Clinical Collection via PubChem
PUBCHEM_SUBSTANCE_COMMENT SAMPLE_SUPPLIER: Sequoia Research Products Ltd.; SUPPLIER_STRUCTURE_ID: SRP01577l NIH Clinical Collection via PubChem

Activity (Go SEA)

Analogs ( Draw Identity 99% 90% 80% 70% )