| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 14th, 2010 | 23 | Yes |
Popular Name: 1-methyl-6-[(4-thiazol-2-ylpiperazin-1-yl)methyl]-5H-pyrazolo[3,4-d]pyrimidin-4-one 1-methyl-6-[(4-thiazol-2-ylpiper…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.08 | 4.39 | -15.96 | 1 | 8 | 0 | 83 | 331.405 | 3 | ↓ |
| Mid Mid (pH 6-8) | 0.08 | 6.58 | -64.16 | 2 | 8 | 1 | 84 | 332.413 | 3 | ↓ |
| Mid Mid (pH 6-8) | 0.54 | 3.8 | -50.26 | 1 | 8 | 0 | 87 | 331.405 | 3 | ↓ |
| Lo Low (pH 4.5-6) | 0.08 | 7.02 | -118.29 | 3 | 8 | 2 | 85 | 333.421 | 3 | ↓ |
No pre-computed analogs available. Try a structural similarity search.
![1,5-dihydropyrazolo[3,4-d]pyrimidin-4-one](http://zinc12.docking.org/img/rings/1171.gif)
![6-[(4-thiazol-2-ylpiperazino)methyl]-1,5-dihydropyrazolo[3,4-d]pyrimidin-4-one](http://zinc12.docking.org/img/rings/24991.gif)