UCSF

ZINC53228198

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
November 18th, 2010 32 Yes

Popular Name: Prulifloxacin Prulifloxacin

Find On: PubMed — Wikipedia — Google

CAS Numbers: 123447-62-1 , 123447-63-2 , 5875-06-9 , [123447-62-1]

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Lo Low (pH 4.5-6) 0.16 11.3 -79.46 2 9 1 110 462.479 4 ↓

Vendor Notes

Note Type Comments Provided By
mechanism . ZereneX Building Blocks
biological_use Antibacterial agent IBScreen Bioactives ZereneX Building Blocks
biological_use Antiseptic IBScreen Bioactives
mechanism Blocker of bacterial DNA replication IBScreen Bioactives IBScreen Bioactives
mechanism Interference with DNA gyrase (supercoiling IBScreen Bioactives
biological_use Prodrug IBScreen Bioactives
mechanism reestablishment of DNA coil integrity during replication) IBScreen Bioactives

Activity (Go SEA)

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.