| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 23rd, 2004 | 20 | Yes |
Popular Name: Oxazepam Oxazepam
Find On: PubMed — Wikipedia — Google
CAS Numbers: 145672-81-7 , 604-75-1
(+-)-7-Chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one
(+-)-Oxazepam; (RS)-Oxazepam; Oxazepam; Serax; Tazepam
1,3-Dihydro-7-chloro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one
1,3-Dihydro-7-chloro-3-hydroxy-5-phenyl-3H-1,4-benzodiazepin-2-one
2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-3-hydroxy-5-phenyl-
2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-3-hydroxy-5-phenyl-, (+-)-
3H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-3-hydroxy-5-phenyl-
604-75-1; D00464; Oxazepam (JAN/USP/INN); Serax (TN)
7-Chloro-1,3-dihydro-3-hydroxy-5-phenyl-1,4(2H)-benzodiazepin-2-one
7-Chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one
7-Chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepine-2-one
7-chloro-3-hydroxy-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
7-Chloro-3-hydroxy-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.84 | 1.04 | -8.23 | 2 | 4 | 0 | 62 | 286.718 | 1 | ↓ |
| Hi High (pH 8-9.5) | 2.02 | -1.08 | -50.39 | 1 | 4 | -1 | 68 | 285.71 | 1 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| ALOGPS_SOLUBILITY | 8.81e-02 g/l | DrugBank-approved |
| PUBCHEM_PATENT_ID | EP0124500A2; EP0307541A2; EP0307541B1; EP0743045A2; EP0743045A3; EP0819142B1; EP0824139B1; US4156013; US4572700; US4622219; US4721709; US4725442; US5589337; US5973089; WO1994001584A1; WO1996015314A1; WO1998000198A1 | IBM Patent Data |
| Patent Database Links | EP0769300; EP1600156; EP1785415; EP1990639; GB2014849; US2004142904; US2004254182; US2005009870; US2005014786; US2005069596; US2005080087; US2005090652; US2005187267; US2007185018; US2007225379; US2007232536; US2007258894; US2008255073; US2008268071; US20 | ChEBI |
