| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 23rd, 2004 | 21 | No |
Popular Name: Tolazamide Tolazamide
Find On: PubMed — Wikipedia — Google
CAS Numbers: 1156-19-0 , [1156-19-0]
1-(((((4-Methylphenyl)sulfonyl)amino)carbonyl)amino)azepane
1-(azepan-1-yl)-3-(4-methylphenyl)sulfonylurea
1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea
1-(Hexahydro-1H-azepin-1-yl)-3-(p-toluenesulfonyl)urea
1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea
1-[({[(4-methylphenyl)sulfonyl]amino}carbonyl)amino]azepane
1156-19-0; CPD000058290; SAM002564236; TOLAZAMIDE
1156-19-0; D00379; Tolazamide (JP16/USP/INN); Tolinase (TN)
1156-19-0; Prestwick_865; Tolazamide
3-azepan-1-yl-1-(4-methylphenyl)sulfonyl-urea
4-(p-Tolylsulfonyl)-1,1-hexamethylene
4-(p-Tolylsulfonyl)-1,1-hexamethylenesemicarbazide
5-20-04-00062 (Beilstein Handbook Reference)
Benzenesulfonamide, N-(((hexahydro-1H-azepin-1-yl)-amino)carbonyl)-4-methyl-
Benzenesulfonamide, N-(((hexahydro-1H-azepin-1-yl)amino)carbonyl)-4-methyl-
Benzenesulfonamide, N-[[(hexahydro-1H-azepin-1-yl)amino]carbonyl]-4-methyl-
Benzenesulfonamide, {N-[[(hexahydro-1H-azepin-1-yl)amino]carbonyl]-4-methyl-}
CPD000058290; SAM002564236; Tolazamide
N-(((Hexahydro-1H-azepin-1-yl)-amino)carbonyl)-4-methylbenzenesulfonamide
N-(((hexahydro-1H-azepin-1-yl)amino)carbonyl)-4-methylbenzenesulfonamide
N-(p-Toluenesulfonyl)-N'-hexamethyleniminourea
N-[(azepan-1-ylamino)carbonyl]-4-methylbenzenesulfonamide
rea, 1-(hexahydroazepin-1-yl)-3-p-tolylsulfonyl-
tolazamida; tolazamide; tolazamidum
Urea, 1-(hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)-
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.15 | 2.32 | -55.88 | 1 | 6 | -1 | 85 | 310.399 | 4 | ↓ |
| Lo Low (pH 4.5-6) | 1.35 | 4.6 | -10.54 | 2 | 6 | 0 | 79 | 311.407 | 3 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| ALOGPS_SOLUBILITY | 3.08e-01 g/l | DrugBank-approved |
| therap | antidiabetic | MicroSource Spectrum |
| PUBCHEM_PATENT_ID | EP0007911A1; EP0028923A1; EP0037672A2; EP0040899A2; EP0052917A2; EP0083032A2; EP0097453A2; EP0104078A2; EP0126684A2; EP0126684B1; EP0145895A1; EP0169105A2; EP0169105B1; EP0182499A1; EP0190969A2; EP0190969B1; EP0206546A2; EP0207605A1; EP0208617A1; EP023300 | IBM Patent Data |
| PUBCHEM_SUBSTANCE_COMMENT | NCC_SAMPLE_SUPPLIER : LightBiologicals; NCC_SUPPLIER_STRUCTURE_ID : T-1375; NCC_SUPPLIER_SAMPLE_COMMENTS : WHITE POWDER | NIH Clinical Collection via PubChem |
| Therapy | Oral hypoglycemic agent; stimulates pancreatic islet cells to secrete insulin | SMDC Iconix |
| Target | Others | Selleck Chemicals |
| PUBCHEM_SUBSTANCE_COMMENT | SAMPLE_SUPPLIER: LightBiologicals; SUPPLIER_STRUCTURE_ID: T-1375; SUPPLIER_COMMENTS: WHITE POWDER | NIH Clinical Collection via PubChem |
No pre-computed analogs available. Try a structural similarity search.