Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.53	1.65	-46.52	0	7	-1	83	394.462	6	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.53	1.81	-52.06	1	7	0	84	395.47	6	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	4.53	1.78	-62.71	1	7	0	84	395.47	6	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	4.53	1.95	-109.55	2	7	1	85	396.478	6	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
AGTR1-1-E	Type-1 Angiotensin II Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	8	0.38	Binding ≤ 10μM
AGTR2-1-E	Angiotensin II Type 2 (AT-2) Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	8	0.38	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
AGTR1_HUMAN	P30556	Angiotensin II Type 1 Receptor, Human	8	0.38	Binding ≤ 1μM
AGTR2_HUMAN	P50052	Angiotensin II Type 2 (AT-2) Receptor, Human	8	0.38	Binding ≤ 1μM
AGTR1_HUMAN	P30556	Angiotensin II Type 1 Receptor, Human	8	0.38	Binding ≤ 10μM
AGTR2_HUMAN	P50052	Angiotensin II Type 2 (AT-2) Receptor, Human	8	0.38	Binding ≤ 10μM

Description	Species
G alpha (i) signalling events	Homo sapiens (AGTR2_HUMAN)
G alpha (q) signalling events	Homo sapiens (AGTR1_HUMAN)
Peptide ligand-binding receptors	Homo sapiens (AGTR1_HUMAN)