UCSF

ZINC00607939

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
July 24th, 2004 27 Yes

Popular Name: Isradipine Isradipine

Find On: PubMed — Wikipedia — Google

CAS Numbers: 1189959-59-8 , 131970-21-3; 75695-93-1 , 75695-93-1 , [75695-93-1]

Other Names:

(+-)-Isradipine

(+-)-Isradipine; 3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester; 3,5-Pyridinedicarboxylic acid, 4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester; 3,5-Pyridinedica

(+/-)-Isradipine

(+/-)-Isradipine;Isradipin;Isradipino [Spanish];Isradipinum [Latin];Isrodipine

(+/-)-Isradipine;Isradipino [Spanish];Isradipinum [Latin];Isrodipine;Isradipin

dipine

pin(e)

2,1,3-Benzoxadiazole, 3,5-pyridinedicarboxylic acid deriv.

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-benzofurazanyl)-2,6-dimethyl-, methyl 1-methylethyl ester, (+-)-

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-benzofurazanyl)-2,6-dimethyl-, methyl 1-methylethyl ester, (+-)-; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-benzofurazanyl)-2,6-dimethyl-,methyl 1-methylethyl ester, (+-)-; C19H21N3O5; Isradipine, (+-)

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-benzofurazanyl)-2,6-dimethyl-,methyl 1-methylethyl ester, (+-)-

3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, 3-methyl 5-(1-methylethyl) ester

3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester

3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester (9CI)

3,5-Pyridinedicarboxylic acid, 4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester

3,5-Pyridinedicarboxylic acid, 4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester, (+-)-

3,5-Pyridinedicarboxylic acid, 4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester, (.+/-.)-

3-O-methyl 5-O-propan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

4-(2,1,3-Benzooxadiazol-4-yl)-2.6-dimethyl-1,4-dihydro-3-isopropyloxycarbonylpyridine-5-carboxylic Acid Methyl Ester

4-(4-Benzofurazanyl)-1,-4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid methyl 1-methhylethyl ester

4-(4-Benzofurazanyl)-1,-4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid methyl 1-methylethyl ester

4-(4-Benzofurazanyl)-1,4-dihydro-2,-6-dimethyl-3,5-pyridinedicarboxylic acid methyl 1-methylethyl ester

75695-93-1

75695-93-1; D00349; Dynacirc (TN); Isradipine (USP/INN)

88977-22-4

AB00514007

AC1L1GPE

AC1Q426L

BAN

BPBio1_001323

BRD-A90799790-001-03-3

BSPBio_001201

C19H21N3O5

CHEMBL1648

CHEMBL315436

CID3784

Clivoten

CPD000466320

CPD000466320; ISRADIPINE

CPD000466320; ISRADIPINE; SAM001246584

D00349

D017275

DAP000134

DB00270

Dynacirc

DynaCirc (TN)

Dynacirc cr

DynaCirc, Prescal, PN-200-110, Clivoten, Esradin

DynaCirc, Prescal, PN-200-110, Clivoten, Esradin, Isradipine

DynaCire

DynaCire CR

Dynacrine

Esradin

FDA

HMS1571M03

HMS2051J12

I06-0364

I6658_SIGMA

Icaz

INN

isopropyl 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-3-pyridinecarboxylate

Isopropyl methyl (+-)-4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate

Isradipin

Isradipine (BAN

Isradipine (Dynacirc)

Isradipine (FDA

Isradipine (USP/INN)

Isradipine [USAN:INN:BAN]

Isradipine, (+-)-Isomer

Isradipine, (R)-Isomer

Isradipine, (S)-Isomer

Isradipine-d3

Isradipino

Isradipino [Spanish]

Isradipinum

Isradipinum [Latin]

Isrodipine

KBio2_000698

KBio2_003266

KBio2_005834

KBioSS_000698

Lomir

LS-131190

LS-177211

methyl 1-methylethyl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

MFCD00153820

MFCD09840821

MLS000759425

MLS001424076

MLS002154106

MolPort-003-848-292

NCGC00025341-02

NCGC00025341-03

O5-methyl O3-propan-2-yl 4-(2,1,3-benzoxadiazol-7-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

PN 200

PN 200-110

PN 205 033

PN 205 034

PN 205-033

PN 205-034

PN 205033

PN 205034

PN-200-110

PN-200110

PN-205-033

PN-205-034

PN205033

PN205034

Prescal

Prestwick0_001021

Prestwick1_001021

Prestwick2_001021

Prestwick3_001021

Rebriden

S1662_Selleck

SAM001246584

SMR000466320

SPBio_003062

Spectrum_000218

UNII-YO1UK1S598

USAN

USP)

Download: MOL2 SDF SMILES Flexibase

Annotations

Vendors

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.81 8.59 -22.3 1 8 0 104 371.393 6 ↓

Vendor Notes

Note Type Comments Provided By
ALOGPS_SOLUBILITY 2.28e-01 g/l DrugBank-approved
Indications antihypertensive KeyOrganics Bioactives
Therapy Ca channel blocker SMDC Pharmakon
therap Ca channel blocker, antiparkisonian MicroSource Spectrum
Target Calcium Channel Selleck Chemicals
Indications hypertension KeyOrganics Bioactives
PUBCHEM_SUBSTANCE_COMMENT NCC_SAMPLE_SUPPLIER : Sequoia Research Products Ltd.; NCC_SUPPLIER_STRUCTURE_ID : SRP01970i NIH Clinical Collection via PubChem
Target Others Selleck Chemicals
PUBCHEM_SUBSTANCE_COMMENT SAMPLE_SUPPLIER: Sequoia Research Products Ltd.; SUPPLIER_STRUCTURE_ID: SRP01970i NIH Clinical Collection via PubChem

Activity (Go SEA)

Analogs ( Draw Identity 99% 90% 80% 70% )