In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
June 21st, 2011 | 36 | No |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 5.65 | 12.47 | -100.75 | 6 | 6 | 2 | 91 | 552.978 | 14 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CNR1-1-E | Cannabinoid CB1 Receptor (cluster #1 Of 5), Eukaryotic | Eukaryotes | 349 | 0.25 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CNR1_HUMAN | P21554 | Cannabinoid CB1 Receptor, Human | 230 | 0.26 | Binding ≤ 1μM |
CNR1_RAT | P20272 | Cannabinoid CB1 Receptor, Rat | 2222 | 0.22 | Binding ≤ 10μM |
CNR1_HUMAN | P21554 | Cannabinoid CB1 Receptor, Human | 230 | 0.26 | Binding ≤ 10μM |
Description | Species |
---|---|
Class A/1 (Rhodopsin-like receptors) | |
G alpha (i) signalling events |