| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 30th, 2011 | 30 | No |
Popular Name: PF-04971729 PF-04971729
Find On: PubMed — Wikipedia — Google
CAS Numbers: 1210344-57-2 , [1210344-57-2]
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.35 | -1.04 | -11.37 | 4 | 7 | 0 | 109 | 436.888 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SC5A1-1-E | Sodium/glucose Cotransporter 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1960 | 0.27 | Binding ≤ 10μM |
| SC5A2-1-E | Sodium/glucose Cotransporter 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.42 | Binding ≤ 10μM |
| SC5A4-1-E | Low Affinity Sodium-glucose Cotransporter (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.42 | Binding ≤ 10μM |
| Z50597-1-O | Rattus Norvegicus (cluster #1 Of 12), Other | Other | 2 | 0.41 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SC5A4_HUMAN | Q9NY91 | Low Affinity Sodium-glucose Cotransporter, Human | 0.877 | 0.42 | Binding ≤ 1μM |
| SC5A2_RAT | P53792 | Sodium/glucose Cotransporter 2, Rat | 1.15 | 0.42 | Binding ≤ 1μM |
| SC5A4_HUMAN | Q9NY91 | Low Affinity Sodium-glucose Cotransporter, Human | 0.877 | 0.42 | Binding ≤ 10μM |
| SC5A1_HUMAN | P13866 | Sodium/glucose Cotransporter 1, Human | 1960 | 0.27 | Binding ≤ 10μM |
| SC5A2_RAT | P53792 | Sodium/glucose Cotransporter 2, Rat | 1.15 | 0.42 | Binding ≤ 10μM |
| Z50597 | Z50597 | Rattus Norvegicus | 1.8 | 0.41 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Hexose transport | |
| Inositol transporters | |
| Na+-dependent glucose transporters |
No pre-computed analogs available. Try a structural similarity search.