| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 26th, 2004 | 20 | Yes |
Popular Name: (4-bromophenyl)-[4-(2,4-dimethylthiazol-5-yl)thiazol-2-yl]amine (4-bromophenyl)-[4-(2,4-dimethyl…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.46 | -1.93 | -7.82 | 1 | 3 | 0 | 37 | 366.309 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TBB3-1-E | Tubulin Beta-3 Chain (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.42 | Binding ≤ 10μM |
| TBB4A-1-E | Tubulin Beta-4 Chain (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.42 | Binding ≤ 10μM |
| TBB4B-1-E | Tubulin Beta-2 Chain (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.42 | Binding ≤ 10μM |
| TBB5-1-E | Tubulin Beta-5 Chain (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.42 | Binding ≤ 10μM |
| TBB8-1-E | Tubulin Beta-8 Chain (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.42 | Binding ≤ 10μM |
| Z80427-1-O | RKO (Colon Carcinoma) (cluster #1 Of 1), Other | Other | 700 | 0.43 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TBB4B_HUMAN | P68371 | Tubulin Beta-2 Chain, Human | 1000 | 0.42 | Binding ≤ 1μM |
| TBB3_HUMAN | Q13509 | Tubulin Beta-3 Chain, Human | 1000 | 0.42 | Binding ≤ 1μM |
| TBB4A_HUMAN | P04350 | Tubulin Beta-4 Chain, Human | 1000 | 0.42 | Binding ≤ 1μM |
| TBB5_HUMAN | P07437 | Tubulin Beta-5 Chain, Human | 1000 | 0.42 | Binding ≤ 1μM |
| TBB8_HUMAN | Q3ZCM7 | Tubulin Beta-8 Chain, Human | 1000 | 0.42 | Binding ≤ 1μM |
| TBB4B_HUMAN | P68371 | Tubulin Beta-2 Chain, Human | 1000 | 0.42 | Binding ≤ 10μM |
| TBB3_HUMAN | Q13509 | Tubulin Beta-3 Chain, Human | 1000 | 0.42 | Binding ≤ 10μM |
| TBB4A_HUMAN | P04350 | Tubulin Beta-4 Chain, Human | 1000 | 0.42 | Binding ≤ 10μM |
| TBB5_HUMAN | P07437 | Tubulin Beta-5 Chain, Human | 1000 | 0.42 | Binding ≤ 10μM |
| TBB8_HUMAN | Q3ZCM7 | Tubulin Beta-8 Chain, Human | 1000 | 0.42 | Binding ≤ 10μM |
| Z80427 | Z80427 | RKO (Colon Carcinoma) | 700 | 0.43 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Formation of tubulin folding intermediates by CCT/TriC | |
| Gap junction assembly | |
| Kinesins | |
| Loss of Nlp from mitotic centrosomes | |
| Loss of proteins required for interphase microtubule organization from the ce | |
| MHC class II antigen presentation | |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | |
| Mitotic Prometaphase | |
| Post-chaperonin tubulin folding pathway | |
| Prefoldin mediated transfer of substrate to CCT/TriC | |
| Recruitment of mitotic centrosome proteins and complexes | |
| Recruitment of NuMA to mitotic centrosomes | |
| Recycling pathway of L1 | |
| Regulation of PLK1 Activity at G2/M Transition | |
| Resolution of Sister Chromatid Cohesion | |
| Separation of Sister Chromatids | |
| Translocation of GLUT4 to the plasma membrane |
No pre-computed analogs available. Try a structural similarity search.