UCSF

ZINC00008492

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
October 11th, 2004 11 Yes

Popular Name: 8-Hydroxyquinoline 8-Hydroxyquinoline

Find On: PubMed — Wikipedia — Google

CAS Numbers: 10380-28-6 , 13014-03-4 , 134-31-6 , 134-31-6, 148-24-3 (base) , 13978-85-3 , 14631-46-0 , 148-24-3 , 15077-57-3 , 16862-11-6 , 207386-91-2 , 2085-33-8 , 2872-54-0 , 65389-08-4 , 6640-50-2 , 8067-69-4 , 850918-68-2 , [134-31-6] , [13978-85-3] , [148-24-3] , [15077-57-3] , [207386-91-2] , [2085-33-8]

Other Names:

"8-Hydroxyquinoline, 99%"

"8-Quinolinol sulfate, 99.5%"

(Bis(8-hydroxyquinolyl)amino)salicylic acid; Benzoic acid, 4-amino-2-hydroxy-, compd. with 8-quinolinol (1:2); Di-8-oxyquinoline-N-aminosalicylic acid; LS-144257; Salicylic acid, (bis(8-hydroxyquinolyl)amino)-

1,2,3,4-Tetrahydro-8-Hydroxyquinoline

1-Azanaphthalene-8-ol; 8-:hydroxyquinoline; 8-Chinolinol [Czech]; 8-HYDROXYQUINOLINE (SEE ALSO 8-HYDROXYQUINOLINE SULFATE 134-31-6; TRANSGENIC MODEL EVALUATION (8-HYD); 8-Hydroxy-chinolin [German]; 8-Hydroxychinolin; 8-Hydroxyquinoline; 8-OQ; 8-Quinolinol

1-Azanaphthalene-8-ol; 8-:hydroxyquinoline; 8-Chinolinol; 8-Chinolinol [Czech]; 8-Hydroxy-chinolin; 8-Hydroxy-chinolin [German]; 8-Hydroxychinolin; 8-Oxychinolin; 8-Oxyquinolin; 8-Oxyquinoline; 8-Quinol; 8-Quinolinol; 8-Quinolinol (7CI,8CI,9CI); 8-quinoli

1-Azanaphthalene-8-ol; 8-Chinolinol; 8-Hydroxy-chinolin; 8-Hydroxyquinoline; 8-OQ; 8-Quinol; 8-quinolinol; Oxyquinoline; quinolin-8-ol

10380-28-6; C18879; Copper 8-hydroxyquinoline; Oxine-copper

134-31-6; C18478; Oxyquinoline sulfate

134-31-6; D02414; Oxyquinoline sulfate (NF)

148-24-3; 8-Hydroxyquinoline; C19434; Oxyquinoline

148-24-3; D05321; Oxyquinoline (USAN)

2-hydroxybenzoic acid compound with 8-quinolinol (1:1); nsc3907

5,6,7,8-Tetrahydroquinolin-8-ol

65389-08-4; D04526; Indium (111In) oxyquinoline solution (JAN); Indium In 111 oxyquinoline (USP); Indium oxine In 111 (TN)

8-(Methylmercurioxy)quinoline; 8-(Quinolinolato)methyl mercury; 8-Quinolinol, mercury complex; Caswell No. 573H; EPA Pesticide Chemical Code 051902; LM seed protectant; LS-89826; Liqui-San; Mercury, (8-quinolinolato)methyl-; Mercury, methyl(8-quinolinolat

8-hydroxy quinoline

8-Hydroxyquinoline aluminum salt

8-Hydroxyquinoline benzoate; 8-Hydroxyquinoline benzoate (salt); 8-Quinolinol benzoate; 8-Quinolinol benzoate (salt); 8-Quinolinol compd. with benzoic acid (1:1); 8-Quinolinol monobenzoate; 8-Quinolinol, benzoate (salt); Benzoic acid, compd. with 8-quinol

8-Hydroxyquinoline copper complex; 8-Quinolinol, copper (II) chelate; 8-Quinolinol, copper salt; 8-Quinolinol, copper(II) chelate; AI3-26537; Bioquin 1; Bis(8-hydroxyquinolinato)copper; Bis(8-oxyquinoline)copper; Bis(8-quinolinato)copper; Bis(8-quinolinat

8-Hydroxyquinoline oxalate; 8-Quinolinol, ethanedioate (salt); 8-Quinolinol, oxalate (salt); LS-142578; Oxalate of 8-oxyquinoline

8-Hydroxyquinoline potassium sulfate

8-Hydroxyquinoline salicylate; 8-Quinolinol, salicylate (salt); Benzoic acid, 2-hydroxy-, compd. with 8-quinolinol (1:1); EINECS 219-457-4; LS-142584; NSC 3907; Salicylate of 8-oxyquinoline; Salicylic acid, compound with quinolin-8-ol (1:1)

8-Hydroxyquinoline succinate; 8-Quinolinol, succinate (salt); Butanedioic acid, compounds, compd. with 8-quinolinol; LS-142585; Succinate of 8-oxyquinoline

8-Hydroxyquinoline sulfate

8-HYDROXYQUINOLINE SULFATE (SEE ALSO 8-HYDROXYQUINOLINE 148-24-3); 8-Hydroxy-chinolin-sulfat [German]; 8-Hydroxyquinoline sulfate; 8-Quinolinol sulfate; 8-Quinolinol sulfate (2:1) (salt); 8-Quinolinol, hydrogen sulfate (2:1); 8-Quinolinol, sulfate (2:1) (

8-Hydroxyquinoline sulfate monohydrate

8-Hydroxyquinoline sulfate monohydrate, 98%

8-Hydroxyquinoline sulfate monohydrate, 99%

8-Hydroxyquinoline sulphate (2:1) monopotassium salt

8-Hydroxyquinoline zinc salt

8-Hydroxyquinoline, 99%

8-Hydroxyquinoline, ACS

8-Hydroxyquinoline, ACS reagent

8-hydroxyquinoline; 8-quinolinol; oxyquinoline

8-Hydroxyquinoline;Oxine

8-Hydroxyquinolinesulfate

8-Hydroxyquinolinezinc

8-Hydroxyquinolinolato-lithium

8-Quinolinol

8-Quinolinol hemisulfate hemihydrate

8-Quinolinol Sulfate Monohydrate

8067-69-4; D04415; Halquinols (USAN); Quinolor (TN)

Aluminium tri(8-quinolinolate)

Antimony(III) oxinate; Antimony, tris(8-quinolinolato)- (6CI,8CI); Antimony, tris(8-quinolinolato-N(sup 1),N(sup 8))-; DV 37; LS-21347; Stibio-oxy-8 quinoleine [French]; Tris(8-quinolinolato-N(sup 1),N(sup 8))antimony

Bis(8-hydroxyquinolinato)zinc

Bis(8-hydroxyquinolinato)zinc, 98%

Bis(8-quinolinolato) zinc

Bis(8-quinolinolato)copper(II)

bis(8-quinolinolato)zinc(ii)

Bis(8-quinolinolato)zinc(II) Hydrate

BRD-K66808046-065-01-1

Copper 8-hydroxyquinoline

DNC010964

Hydroxyquinoline sulfate

Indium In-111 Oxyquinoline; Indium in 111 oxyquinoline; Indium in 111 oxyquinoline [USAN]; Indium-(sup 111)In, tris(8-quinolinolato-N(sup 1),O(sup 8))-; Indium-(sup 111)In, tris(8-quinolinolato-kappaN1,kappaO8)-; LS-186482; MPI Indium Oxine In 111; Tris(8

LS-190401

LS-88583

MFCD00006807

MFCD00013095

MFCD00035258

MFCD00065291

MFCD00067392

MFCD00143521

MFCD00149610

MFCD00152803

MFCD00191693

MFCD08062407

N/A

NA

Oxine

OXINE-COPPER

oxyquinoline

Oxyquinoline (USAN); Oxyquinoline Sulfate (NF

OXYQUINOLINE HEMISULFATE

OXYQUINOLINE SULFATE

Oxyquinoline Sulfate (NF

Potassium-8-hydroxyquinoline sulfate

quinolin-8-ol

Quinolin-8-ol hydrochloride

Quinolin-8-ol sulfate

Quinolin-8-ol sulfate hydrate(2:1:1)

Quinoline Sulphate

Sodium-8-oxyquinolate

Tris(8-hydroxyquinolinato)aluminum, 99%

Tris(8-quinolinolato)aluminum

Tris(8-quinolinolato)aluminum (purified by sublimation)

USAN)

USAN); Oxyquinoline (USAN)

Zinc 8-hydroxyquinolinate

Download: MOL2 SDF SMILES Flexibase

Annotations

Vendors

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.68 2.1 -8.63 1 2 0 33 145.161 0 ↓
Hi High (pH 8-9.5) 1.68 2.86 -52.15 0 2 -1 36 144.153 0 ↓
Lo Low (pH 4.5-6) 1.68 2.58 -30.13 2 2 1 34 146.169 0 ↓

Vendor Notes

Note Type Comments Provided By
BP 126 / 10 TCI
Melting_Point 151? Alfa-Aesar
Melting_Point 151° Alfa-Aesar
Melting_Point 176-179? Alfa-Aesar
Melting_Point 176-179° Alfa-Aesar
MP 178 TCI
Mp [°C] 182 Acros Organics
BP [°C] 267 (p=752 torr) Acros Organics
Boiling_Point 267? Alfa-Aesar
Boiling_Point 267° Alfa-Aesar
BP 267°/752mm Oakwood Chemical
UniProt Database Links 6HN3M_PSEFL; LAAA_PSEAZ; LAAA_PSEFS; MPHES_MICSP; NAHC1_PSEPU; NFDA_ARTPS; NQOR_ECOLI; Q2OA_COMTE; Q2OB_COMTE; Q2OG_COMTE; RSAM_PSESP ChEBI
MP 70-73° Oakwood Chemical
Mp [°C] 72 - 74 Acros Organics
Melting_Point 72-74? Alfa-Aesar
Melting_Point 72-74° Alfa-Aesar
Melting_Point 72-76? Alfa-Aesar
Melting_Point 72-76° Alfa-Aesar
MP 72...74 Enamine Building Blocks
MP 75 TCI
MP 75 - 77 Enamine Building Blocks
purity 9.500000000000000e+001 Enamine Building Blocks Enamine Building Blocks
Purity 95% Fluorochem
Purity 98% Fluorochem
Purity 99% APIChem
Melting_Point >300? Alfa-Aesar
therap antiinfectant MicroSource Pharmakon
therap antiinfectant, complexing agent MicroSource Spectrum
Therapy disinfectant SMDC Iconix
Patent Database Links EP0862353; EP1659129; EP1661886; GB2048064; US2007027154; US2007254018; WO2005082352; WO2005108372; WO2007097818; WO2008112280 ChEBI
H phrase H302: Harmful if swallowed Acros Organics
H phrase H319: Causes serious eye irritation Acros Organics
H phrase H319: Causes serious eye irritation; H315: Causes skin irritation; H335: May cause respiratory irritation; H332: Harmful if inhaled; H312: Harmful in contact with skin; H302: Harmful if swallowed; H341: Suspected of causing genetic defects Acros Organics
P phrase P281: Use personal protective equipment as required Acros Organics
P phrase P281: Use personal protective equipment as required; P260: Do not breathe dust/fume/gas/mist/vapors/spray; P301+ P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell; P304 + P340: IF INHALED: Remove victim to fresh air and keep Acros Organics
P phrase P301+ P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell Acros Organics
PUBCHEM_SUBSTANCE_COMMENT pending PDSP via PubChem
R phrase R20/21/22: Harmful by inhalation, in contact with skin and if swallowed. Acros Organics
R phrase R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.; R36/37/38: Irritating to eyes, respiratory system and skin.; R68: Possible risks of irreversible effects. Acros Organics
R phrase R22: Harmful if swallowed. Acros Organics
S phrase S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Acros Organics
S phrase S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.; S45: In case of accident or if you feel unwell, seek medical advice immediat Acros Organics
S phrase S36: Wear suitable protective clothing. Acros Organics
Hazard XN: Harmful Acros Organics

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
AMPM2-2-E Methionine Aminopeptidase 2 (cluster #2 Of 2), Eukaryotic Eukaryotes 5600 0.67 Binding ≤ 10μM
Z101736-1-O Colletotrichum Coccodes (cluster #1 Of 1), Other Other 190 0.86 Functional ≤ 10μM
Z80136-1-O FM3A (Breast Carcinoma Cells) (cluster #1 Of 6), Other Other 2100 0.72 Functional ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
AMPM2_HUMAN P50579 Methionine Aminopeptidase 2, Human 5600 0.67 Binding ≤ 10μM
Z101736 Z101736 Colletotrichum Coccodes 190 0.86 Functional ≤ 10μM
Z80136 Z80136 FM3A (Breast Carcinoma Cells) 2100 0.72 Functional ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description Species
Inactivation, recovery and regulation of the phototransduction cascade

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.