UCSF

ZINC00895360

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
October 3rd, 2005 8 Yes

Popular Name: L-Proline L-Proline

Find On: PubMed — Wikipedia — Google

CAS Numbers: 147-85-3 , 15383-56-9 , 26166-36-9 , 282729-06-0 , 344-25-2 , 53912-85-9 , 609-36-9 , 7776-34-3 , [147-85-3] , [15383-56-9] , [609-36-9] , [7776-34-3]

Other Names:

"L-Proline, 99%"

(+/-)-Pyrrolidine-2-carboxylic acid

(-)-(S)-Proline

(-)-(S)-Proline; (-)-2-Pyrrolidinecarboxylate; (-)-2-Pyrrolidinecarboxylic acid; (-)-Proline; (S)-(-)-Proline; (S)-(-)-Pyrrolidine-2-carboxylate; (S)-(-)-Pyrrolidine-2-carboxylic acid; (S)-2-Carboxypyrrolidine; (S)-2-Pyrralidinecarboxylate; (S)-2-Pyrralid

(-)-(S)-proline; (-)-2-pyrrolidinecarboxylic acid; (-)-proline; (2S)-pyrrolidine-2-carboxylic acid; (S)-2-carboxypyrrolidine; (S)-2-pyrrolidinecarboxylic acid; (S)-pyrrolidine-2-carboxylic acid; L-(-)-proline; L-Prolin; L-alpha-pyrrolidinecarboxylic acid

(-)-(S)-Proline; (-)-2-Pyrrolidinecarboxylic acid; (-)-Proline; (L)-Proline; (S)-2-Pyrrolidinecarboxylic acid; 2-Pyrrolidinecarboxylic acid, (S)-; AI3-26710; CB 1707; EINECS 205-702-2; FEMA No. 3319; FEMA Number 3319; HSDB 1210; L-(-)-Proline; L-Proline

(-)-(S)-Proline; (-)-2-Pyrrolidinecarboxylic acid; (-)-Proline; (L)-PROLINE; (S)-2-Pyrrolidinecarboxylic acid; 2-Pyrrolidinecarboxylic acid; 2-Pyrrolidinecarboxylic acid, (S)-; AI3-26710; CB 1707; L-(-)-Proline; L-Proline; L-Pyrrolidine-2-carboxylic acid

(-)-(S)-Proline;(-)-2-Pyrrolidinecarboxylate;(-)-2-Pyrrolidinecarboxylic acid;(-)-Proline;(S)-(-)-Proline;(S)-(-)-Pyrrolidine-2-carboxylate;(S)-(-)-Pyrrolidine-2-carboxylic acid;(S)-2-Carboxypyrrolidine;(S)-2-Pyrralidinecarboxylate;(S)-2-Pyrralidinecarbox

(-)-2-Pyrrolidinecarboxylic acid

(-)-Proline

(-)-Proline (S)-2-Carboxypyrrolidine

(2R)-Pyrrolidine-2-carboxylic acid

(2S)-pyrrolidine-2-carboxylic acid

(L)-PROLINE

(S)-2-Carboxypyrrolidine

(S)-2-Pyrrolidinecarboxylic acid

(S)-Proline

(S)-Pyrrolidine-2-carboxylic acid

(S)-Pyrrolidine-2-carboxylic acid hydrochloride

(S)-Pyrrolidine-2-carboxylicacidhydrochloride

147-85-3

147-85-3; 2-Pyrrolidinecarboxylic acid; C00148; L-Proline

147-85-3; 2-pyrrolidinecarboxylic acid; L-proline; pro; prol; proline

147-85-3; D00035; L-Proline (JP16); Proline (USP)

18875-45-1

2-Pyrrolidinecarboxylic acid

2-Pyrrolidinecarboxylic acid, (S)-

2-Pyrrolidinecarboxylicacid

37159-97-0

4305-67-3

4607-28-7

608998_ALDRICH

609-36-9; C16435; DL-Proline; Proline

609-36-9; nsc97923; proline

81709_FLUKA

81709_SIGMA

81710_FLUKA

81710_SIGMA

A01B5B63-CC3D-4796-A7B4-C2DE26A6FA93

AB1002323

AC-11190

AC1L3RTC

AC1Q71B7

AI3-26710

AmbotzHAA1126

bmse000047

C00148

Carboxypyrrolidine

CB 1707

CHEBI:17203

CHEBI:184637; CHEBI:45159; CHEBI:45100; CHEBI:45040; CHEBI:42067; CHEBI:13154; CHEBI:21373; CHEBI:6286

CHEBI:58054

CHEMBL54922

CID145742

D-Proline

D-Pyrrolidine-2-carboxylic acid

D00035

DAP000198

DB00172

DB02853

DL-Proline

DL-Proline [609-36-9]

DL-Proline, 99%

DL-PROLINE-2-D1

DL-PROLINE; [609-36-9]

DL-Pyrrolidine-2-carboxylic acid

EINECS 205-702-2

FEMA No. 3319

FEMA Number 3319

H-DL-Pro-OH

H-Pro-OH

HSDB 1210

L(-)-Proline, 99+%

L-(-)-proline

L-(2,3-3H)Proline

L-alpha-Pyrrolidinecarboxylic acid

L-beta-Homoproline hydrochloride

L-Prolin

L-Proline (JAN)

L-Proline sodium salt

L-proline zwitterion

L-Proline [147-85-3]

L-Proline, 99%

L-Proline, labeled with carbon-14

L-Proline-15N

L-PROLINE; [147-85-3]

L-Pyrrolidine-2-carboxylic acid

LS-2381

MFCD00005250

MFCD00063720

MFCD00064318

MFCD03791121

MFCD23699510

MFCD26936305

MolPort-001-757-108

NCGC00014017

NCGC00097126-01

nchembio.186-comp54

nchembio816-comp9

NSC 46703

NSC-97923

OR-0258

OT-2488

P0380_SIAL

P0481

P5607_SIGMA

P8865_SIAL

P8865_SIGMA

pro

PRO (IUPAC abbreviation)

prolina

Prolina [Spanish]

Proline

Proline (INN

Proline (USP)

Proline (VAN)

PROLINE L-

Proline [USAN:INN]

Proline, L-

Prolinum

Prolinum [Latin]

pyrrolidine-2-carboxylic acid

pyrrolidine-2-carboxylic acid hydrochloride

Sodium L-prolinate

TL80073505

UNII-9DLQ4CIU6V

USAN

USP)

W331902_ALDRICH

Download: MOL2 SDF SMILES Flexibase

Annotations

Vendors

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -1.72 2.43 -35.08 2 3 0 57 115.132 1 ↓

Vendor Notes

Note Type Comments Provided By
UniProt Database Links 002L_FRG3G; 011L_IIV3; 020R_FRG3G; 034R_IIV6; 035L_FRG3G; 073R_IIV3; 084L_IIV6; 104K_THEPA; 119R_IIV3; 132L_IIV6; 14KD_DAUCA; 165R_IIV6; 1A11_ARATH; 1AP1_BRAOT; 2A5B_ARATH; 2AP1_BRAOT; 3AP1_BRAOL; 3BP2_HUMAN; 3BP2_MOUSE; 457L_IIV6; 4CLL5_ORYSJ; 4CLL6_ORYS ChEBI
MP 208 °C (dec.)(lit.) Indofine
MP 223 - 225 Enamine Building Blocks
MP 223...225 Enamine Building Blocks
Mp [°C] 228 - 233 Acros Organics
MP 228 °C (dec.)(lit.) Indofine
MP 228° Matrix Scientific
ALOGPS_SOLUBILITY 3.65e+02 g/l DrugBank-experimental
purity 9.500000000000000e+001 Enamine Building Blocks Enamine Building Blocks
Purity 95+% Matrix Scientific
Purity 97% APIChem
Purity 98% Fluorochem
UniProt Database Links AACL_AGRT5; AAP1_ARATH; AL121_ARATH; AL4A1_BOVIN; AL4A1_DANRE; AL4A1_DICDI; AL4A1_HUMAN; AL4A1_MOUSE; AL4A1_RAT; ALH13_CAEEL; FAP1_SCHPO; FTMA_ASPFM; FTMA_ASPFU; FTMA_NEOFI; GNAT3_MOUSE; LAAA_PSEAZ; LAAA_PSEFS; LHT1_ARATH; OAT1_STAAC; OAT1_STAAM; OAT1_STA ChEBI
Melting_Point ca 209? dec. Alfa-Aesar
Melting_Point ca 209° dec. Alfa-Aesar
Melting_Point ca 225? dec. Alfa-Aesar
Melting_Point ca 225° dec. Alfa-Aesar
Patent Database Links EP0889031; EP0928790; EP1308439; EP1514554; EP1532983; EP1541585; EP1568283; EP1588715; EP1609462; EP1616963; EP1627884; EP1632233; EP1661565; EP1762232; EP1849466; EP1950199; EP1983044; GB1212533; US2004034080; US2005101540; US2005197498; US2005215573; U ChEBI
SOLUBILITY H2O: 50 mg/mL Indofine
Warnings IRRITANT Matrix Scientific
Reactome Database Links REACT_111140; REACT_111222; REACT_119; REACT_13449; REACT_13591; REACT_13593; REACT_14785; REACT_14841; REACT_15310; REACT_15436; REACT_1563; REACT_19313; REACT_19377; REACT_20557; REACT_75867; REACT_75920 ChEBI
S phrase S24/25: Avoid contact with skin and eyes. Acros Organics

Activity (Go SEA)

Direct Reactome Annotations (via ChEBI)

Description Species
Amino acid synthesis and interconversion (transamination)
Amino acid transport across the plasma membrane
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Antigen processing: Ubiquitination & Proteasome degradation
Cross-presentation of soluble exogenous antigens (endosomes)
Cytosolic tRNA aminoacylation
Endosomal/Vacuolar pathway
ER-Phagosome pathway
Glutathione synthesis and recycling
Mitochondrial tRNA aminoacylation
Na+/Cl- dependent neurotransmitter transporters
Proline catabolism
Proton-coupled neutral amino acid transporters
Proton/oligonucleotide cotransporters

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.