| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 30th, 2005 | 8 | Yes |
Popular Name: Tris(hydroxymethyl)aminomethane Tris(hydroxymethyl)aminomethane
Find On: PubMed — Wikipedia — Google
CAS Numbers: 108321-11-5 , 108321-13-7 , 1185-53-1 , 68123-29-5 , 6850-28-8 , 6992-39-8 , 72200-76-1 , 77-86-1 , N/A , [1185-53-1] , [68123-29-5] , [6850-28-8] , [77-86-1]
"Tris(hydroxymethyl)aminomethane hydrochloride, 99%"
"Tris(hydroxymethyl)aminomethane, 99.5%"
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
2-amino-2-(hydroxymethyl)-1,3-propanediol
2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride
2-Amino-2-(hydroxymethyl)-1,3-propanediol; 77-86-1; C07182; Trometamol; Tromethamine
2-amino-2-(hydroxymethyl)propane-1,3-diol
2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride
2-amino-2-(hydroxymethyl)propane-1,3-diol; phosphoric acid
2-Amino-2-hydroxymethyl-1,3-propanediol
2-Amino-2-hydroxymethyl-1,3-propanediol hydrochloride
77-86-1; D00396; THAM (TN); Trometamol (JAN/INN); Tromethamine (USP)
Di(tris[hydroxymethyl]aminomethane) oxalate
DI[TRIS AMINOMETHANE]PHOSPHATE
DI[TRIS(HYDROXYMETHYL)AMINOMETHANE] PHOSPHATE
Tri(hydroxymethyl)aminomethane
Tris HCl, mole-ready form, molecular biology grade
tris(hydroxymethyl)aminomethane acetate
Tris(hydroxymethyl)aminomethane acetate salt
Tris(hydroxymethyl)aminomethane acetate salt, 99%
Tris(hydroxymethyl)aminomethane HCl
Tris(hydroxymethyl)aminomethane hydrochloride
Tris(hydroxymethyl)aminomethane hydrochloride, 99+%
Tris(hydroxymethyl)aminomethane hydrochloride, 99+%, extra pure
Tris(hydroxymethyl)aminomethane phosphate
Tris(hydroxymethyl)aminomethane [for Electrophoresis]
Tris(hydroxymethyl)aminomethane, 99%
Tris(hydroxymethyl)aminomethane, 99+%, for biochemistry
Tris(hydroxymethyl)aminomethane, 99.8%, ACS reagent
Tris(hydroxymethyl)aminomethane, ACS
Tris(hydroxymethyl)aminomethane, ACS, 99.8-100.1% (Assay, dried basis)
TRIS(HYDROXYMETHYL)AMINOMETHANE, ULTRAPURE >99.9%; [77-86-1]
Tris(Hydroxymethyl)Aminomethane, Ultrapure [77-86-1]; (Tris Ultrapure)
tris-(Hydroxymethyl) aminomethane acetate
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -2.12 | -8.75 | -35.82 | 6 | 4 | 1 | 88 | 122.144 | 3 | ↓ |
| Mid Mid (pH 6-8) | -2.12 | -9.08 | -5.86 | 5 | 4 | 0 | 87 | 121.136 | 3 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| Mp [°C] | 150 - 153 | Acros Organics |
| MP | 16 - 18 | Enamine Building Blocks |
| MP | 16...18 | Enamine Building Blocks |
| M.P | 167-172 °C | Indofine |
| Melting_Point | 168-172? | Alfa-Aesar |
| Melting_Point | 168-172° | Alfa-Aesar |
| Melting_Point | 171-172? | Alfa-Aesar |
| Melting_Point | 171-172° | Alfa-Aesar |
| BP [°C] | 219 - 220 (p=10 torr) | Acros Organics |
| Boiling_Point | 219-220?/10mm | Alfa-Aesar |
| Boiling_Point | 219-220°/10mm | Alfa-Aesar |
| BP | 220 / 10 | TCI |
| ALOGPS_SOLUBILITY | 3.70e+02 g/l | DrugBank-experimental |
| purity | 9.500000000000000e+001 | Enamine Building Blocks Enamine Building Blocks |
| Purity | 99% | Fluorochem |
| Mp [°C] | >168.5 | Acros Organics |
| Purity | >99% | Fluorochem |
| Melting_Point | ca 152? dec. | Alfa-Aesar |
| Melting_Point | ca 152° dec. | Alfa-Aesar |
| UniProt Database Links | CATLL_FASHE; CDCA7_RAT; CNDP1_HUMAN; DAPAT_ARATH; DPP4_MOUSE; HCNA_PSEAE; HCNB_PSEAE; HCNC_PSEAE; HTN_HAEGH; MGM_EUBBA; OAME_CLOSD; OAMS_CLOSD; OLHYD_ELIME; PDXA_ECOLI; QHED_PSEPU; SCP19_ARATH; TALB_ECOLI | ChEBI |
| Target | COX | Selleck Chemicals |
| Patent Database Links | EP1004623; EP1151994; EP1619190; EP1655022; EP1785133; EP1806400; EP1808492; EP1818049; GB1440998; US2001025035; US2003068379; US2003199577; US2003229083; US2004059120; US2004097593; US2005026911; US2005031545; US2005101603; US2005113368; US2005124656; US | ChEBI |
| SOLUBILITY | H2O: 4 M at 20 °C, clear, colorless | Indofine |
| H phrase | H315: Causes skin irritation | Acros Organics |
| H phrase | H335: May cause respiratory irritation | Acros Organics |
| H phrase | H335: May cause respiratory irritation; H319: Causes serious eye irritation; H315: Causes skin irritation | Acros Organics |
| Notes | Loss on drying: <0.2%Heavy metals: <1ppm pka: @ 20°C:8.3 + 0.1Biological buffer - useful range 7.0-9.0 | Apollo Scientific Bioactives |
| Target | Others | Selleck Chemicals |
| P phrase | P261: Avoid breathing dust/fume/gas/mist/vapors/spray | Acros Organics |
| P phrase | P261: Avoid breathing dust/fume/gas/mist/vapors/spray; P302+ P352: IF ON SKIN: Wash with plenty of soap and water; P280: Wear protective gloves/protective clothing/eye protection/face protection; P305 + P351 + P338: IF IN EYES: Rinse cautiously with water | Acros Organics |
| P phrase | P280: Wear protective gloves/protective clothing/eye protection/face protection | Acros Organics |
| R phrase | R36/37/38: Irritating to eyes, respiratory system and skin. | Acros Organics |
| S phrase | S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. | Acros Organics |
| S phrase | S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39: Wear suitable gloves and eye/face protection. | Acros Organics |
| Patent Database Links | US2006166996 | ChEBI |
| Hazard | XI: Irritant | Acros Organics |
No pre-computed analogs available. Try a structural similarity search.