| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 27th, 2005 | 24 | Yes |
Popular Name: Metolazone Metolazone
Find On: PubMed — Wikipedia — Google
CAS Numbers: 17560-51-9 , [17560-51-9]
17560-51-9; D00431; Metolazone (JAN/USP/INN); Zaroxolyn (TN)
17560-51-9; Metolazone; Prestwick_333
2-Methyl-3-o-tolyl-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone
5-25-09-00212 (Beilstein Handbook Reference)
6-Quinazolinesulfonamide, 1,2,3,4-tetrahydro-7-chloro-2-methyl-4-oxo-3-o-tolyl-
6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-
6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-
7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide
7-Chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamide
7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2-dihydroquinazoline-6-sulfonamide
7-Chloro-2-methyl-4-oxo-3-(o-tolyl)-1,2,3,4-tetrahydroquinazoline-6-sulfonamide
Metolazona [INN-Spanish]; Metolazonum [INN-Latin]
Metolazona [INN-Spanish];Metolazonum [INN-Latin]
metolazona; metolazone; metolazonum
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.77 | 3.71 | -17.08 | 3 | 6 | 0 | 93 | 365.842 | 2 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| MP | 255-257° | Oakwood Chemical |
| ALOGPS_SOLUBILITY | 4.07e-02 g/l | DrugBank-approved |
| Purity | 95% | Fluorochem |
| Therapy | diuretic, antihypertensive | SMDC Iconix |
| Target | Others | Selleck Chemicals |
