UCSF

ZINC00897232

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
July 28th, 2004 20 No

Popular Name: Methyclothiazide Methyclothiazide

Find On: PubMed — Wikipedia — Google

CAS Number: 135-07-9

Other Names:

(+-)-6-Chloro-3-(chloromethyl)-3,4-dihydro-2-methyl-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

(+-)-6-Chloro-3-(chloromethyl)-3,4-dihydro-2-methyl-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(chloromethyl)-3,4-dihydro-,1,1-dioxide; 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(chlo

thiazide

135-07-9

135-07-9; C07765; Methyclothiazide

135-07-9; D00656; Enduron (TN); Methyclothiazide (JAN/USP/INN)

2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(chloromethyl)-3,4-dihydro-,1,1-dioxide

2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(chloromethyl)-3,4-dihydro-2-methyl-, 1,1-dioxid

2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(chloromethyl)-3,4-dihydro-2-methyl-, 1,1-dioxide

2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(chloromethyl)-3,4-dihydro-2-methyl-, 1,1-dioxide, (+-)-

6-chloro-3-(chloromethyl)-2-methyl-1,1-dioxo-3,4-dihydro-1

6-chloro-3-(chloromethyl)-2-methyl-1,1-dioxo-3,4-dihydro-1$l^{6},2,4-benzothiadiazine-7-sulfonamide

6-chloro-3-(chloromethyl)-2-methyl-1,1-dioxo-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide

6-Chloro-3-(chloromethyl)-2-methyl-3,4-dihydro--2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

6-Chloro-3-(chloromethyl)-2-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

6-Chloro-3-(chloromethyl)-3,4-dihydro-2-methyl-2H-1,2, 4-benzothiadiazine-7-sulfonamide 1,1-dioxide

6-Chloro-3-(chloromethyl)-3,4-dihydro-2-methyl-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

6-Chloro-3-chloromethyl-2-methyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide

AC1L1HGJ

AC1Q6TPS

Aquaresen

Aquatensen

AR-1J4220

BAN

BRN 0765361

C07765

C11H13N.C9H11Cl2N3O4S2.Cl; EUTRON; LS-178549; METHYCLOTHIAZIDE; PARGYLINE HYDROCHLORIDE

C9H11Cl2N3O4S2

CHEMBL1577

CI-625

Ciba 7272-Su

CID4121

D00656

DAP000746

DB00232

Duretic

EINECS 205-172-2

Enduron

Enduron (TN)

Enduronum

FDA

HSDB 3363

I06-1878

INN

JAN

LS-40433

Methychlothiazide

Methychlothiazide; Methyclothiazid; Methycyclothiazide; Methylchlorothiazide; Methylclothiazide; Methylcyclothiazide

Methychlothiazide;Methyclothiazid;Methycyclothiazide;Methylchlorothiazide;Methylclothiazide;Methylcyclothiazide

Methyclothiazid

Methyclothiazide (BAN

Methyclothiazide (FDA

Methyclothiazide (JAN/USP/INN)

Methyclothiazide [USAN:INN:BAN:JAN]

Methyclothiazidum

Methyclothiazidum [INN-Latin]

Methycyclothiazide

Methylchlorothiazide

Methylclothiazide

Methylcyclothiazide

Meticlotiazida

Meticlotiazida [INN-Spanish]

Meticlotiazide

Meticlotiazide [DCIT]

MFCD00242610

MLS002704228

N/A

Naturon

Naturon (VAN)

NCGC00167446-01

NSC 110431

NSC-110431

NSC110431

QA-7978

SBB070984

SMR001550236

UNII-L3H46UAC61

USAN

USP)

WLN: T66 BSWN EM DHJ C1 D1G HG ISZW

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 0.78 -2.62 -17.33 3 7 0 110 360.244 2 ↓

Vendor Notes

Note Type Comments Provided By
ALOGPS_SOLUBILITY 8.24e-01 g/l DrugBank-approved
purity 9.500000000000000e+001 Enamine Building Blocks Enamine Building Blocks
Therapy antihypertensive SMDC Iconix
Target Others Selleck Chemicals

Activity (Go SEA)

Analogs ( Draw Identity 99% 90% 80% 70% )