UCSF

ZINC95616601

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
January 13th, 2014 0 Yes

Popular Name: Prazosin hydrochloride Prazosin hydrochloride

Find On: PubMed — Wikipedia — Google

CAS Numbers: 19216-56-9 , 19237-84-4 , 86126-06-9 , [19216-56-9] , [19237-84-4]

Other Names:

(4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(furan-2-yl)methanone

(4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(furan-2-yl)methanone hydrochloride salt

azosin

1-(3-AMINO-6,7-DIMETHOXY-2-QUINAZOLINY)-4-(2-FURANYLCARBONYL)PIPERAZINE

1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine hydrochloride; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl)piperazine monohydrochloride; 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline hydrochloride; C19H2

1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine; 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline; Prazosin

19216-56-9; C07368; Prazosin

19216-56-9; D08411; Minipress (TN); Prazosin (INN)

19237-84-4; D00609; Minipress (TN); Prazosin hydrochloride (JP16/USP)

BRD-K49111258-003-05-7

CP-12299

CP-12299-1

CP-12299; CP-122991; CP-12299-1

CPD000449301; Prazosin; SAM001246995

FDA)

Furazosin

INN)

INN); Prazosin HCl (FDA

INN); Prazosin HCl (JAN

JAN

Lentopres

LS-188028; MINIZIDE; POLYTHIAZIDE; PRAZOSIN HYDROCHLORIDE

MFCD00058177

MFCD00599563

Minipress

Minipress Xl

Minipress,Vasoflex,Pressin and Hypovase

Prazocin

Prazocin;Prazosina [INN-Spanish];Prazosine [INN-French];Prazosinum [INN-Latin]

Prazosin

Prazosin (BAN

Prazosin HCl

Prazosin Hydrochloride (FDA

prazosin; prazosina; prazosine; prazosinum

Prazosin;Minipress;Pressin

Prazosina [INN-Spanish]

Prazosine [INN-French]

Prazosinum [INN-Latin]

QA-1400

USAN

USP

USP)

USP); Prazosin (BAN

Vasoflex

[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl](2-furyl)methanone

[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl](furan-2-yl)methanone

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL

Vendor Notes

Note Type Comments Provided By
ALOGPS_SOLUBILITY 6.93e-01 g/l DrugBank-approved
Purity 95% Fluorochem
UniProt Database Links ADA2A_HUMAN; ADA2B_HUMAN; OAR1_LYMST; OAR2_LYMST; S22A1_BOVIN; S22A1_HUMAN; S22A1_MOUSE; S22A1_PIG; S22A1_RABIT; S22A1_RAT ChEBI
mechanism Alpha 2B -Adrenoceptor antagonist, IBScreen Bioactives
biological_use Antihypertensive agent IBScreen Bioactives
Indications antihypertensive, anxiety/panic KeyOrganics Bioactives
Patent Database Links EP1106210; EP1454902; EP1649855; EP1671630; EP1681051; EP1717226; EP1728508; EP1749540; EP1790343; EP1862181; EP1894567; EP1939188; EP1946777; EP1967202; EP1988098; GB2264710; US2004147575; US2004254182; US2005065209; US2005085497; US2005119312; US2005124 ChEBI
mechanism Melatonin MT 3 -receptor antagonist IBScreen Bioactives
PUBCHEM_SUBSTANCE_COMMENT NCC_SAMPLE_SUPPLIER : Tocris Cookson Ltd.; NCC_SUPPLIER_STRUCTURE_ID : 100730; .75 water; 1 hydrogen chloride NIH Clinical Collection via PubChem
Target Others Selleck Chemicals
PUBCHEM_SUBSTANCE_COMMENT SAMPLE_SUPPLIER: Tocris Bioscience; SUPPLIER_STRUCTURE_ID: 100730; SALT: .75 water; 1 hydrogen chloride NIH Clinical Collection via PubChem

Activity (Go SEA)

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.